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Items: 1 to 20 of 131

1.

Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs.

Winkler T, Hong SG, Decker JE, Morgan MJ, Wu C, Hughes WM 5th, Yang Y, Wangsa D, Padilla-Nash HM, Ried T, Young NS, Dunbar CE, Calado RT.

J Clin Invest. 2013 May;123(5):1952-63. doi: 10.1172/JCI67146. Epub 2013 Apr 15.

2.

Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells.

Wang F, Yin Y, Ye X, Liu K, Zhu H, Wang L, Chiourea M, Okuka M, Ji G, Dan J, Zuo B, Li M, Zhang Q, Liu N, Chen L, Pan X, Gagos S, Keefe DL, Liu L.

Cell Res. 2012 Apr;22(4):757-68. doi: 10.1038/cr.2011.201. Epub 2011 Dec 20.

3.

Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells.

Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, Reijo Pera RA, Artandi SE.

Nature. 2011 May 22;474(7351):399-402. doi: 10.1038/nature10084.

4.

Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia.

Yamaguchi H, Calado RT, Ly H, Kajigaya S, Baerlocher GM, Chanock SJ, Lansdorp PM, Young NS.

N Engl J Med. 2005 Apr 7;352(14):1413-24.

5.

Prognostic value of telomere attrition in patients with aplastic anemia.

Scheinberg P.

Int J Hematol. 2013 May;97(5):553-7. doi: 10.1007/s12185-013-1332-x. Epub 2013 May 1. Review.

PMID:
23636667
6.

Functional characterization of novel telomerase RNA (TERC) mutations in patients with diverse clinical and pathological presentations.

Marrone A, Sokhal P, Walne A, Beswick R, Kirwan M, Killick S, Williams M, Marsh J, Vulliamy T, Dokal I.

Haematologica. 2007 Aug;92(8):1013-20. Epub 2007 Jul 20.

7.

Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice.

Raval A, Behbehani GK, Nguyen le XT, Thomas D, Kusler B, Garbuzov A, Ramunas J, Holbrook C, Park CY, Blau H, Nolan GP, Artandi SE, Mitchell BS.

PLoS One. 2015 Jul 2;10(7):e0131722. doi: 10.1371/journal.pone.0131722. eCollection 2015.

8.

A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis.

Imamura S, Uchiyama J, Koshimizu E, Hanai J, Raftopoulou C, Murphey RD, Bayliss PE, Imai Y, Burns CE, Masutomi K, Gagos S, Zon LI, Roberts TM, Kishi S.

PLoS One. 2008;3(10):e3364. doi: 10.1371/journal.pone.0003364. Epub 2008 Oct 10.

9.

Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to induced pluripotent stem cells.

Le R, Kou Z, Jiang Y, Li M, Huang B, Liu W, Li H, Kou X, He W, Rudolph KL, Ju Z, Gao S.

Cell Stem Cell. 2014 Jan 2;14(1):27-39. doi: 10.1016/j.stem.2013.11.005. Epub 2013 Nov 21.

10.

Telomere maintenance and human bone marrow failure.

Calado RT, Young NS.

Blood. 2008 May 1;111(9):4446-55. doi: 10.1182/blood-2007-08-019729. Epub 2008 Jan 31. Review.

11.

Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts.

Westin ER, Chavez E, Lee KM, Gourronc FA, Riley S, Lansdorp PM, Goldman FD, Klingelhutz AJ.

Aging Cell. 2007 Jun;6(3):383-94. Epub 2007 Mar 23.

12.

Telomere length is inherited with resetting of the telomere set-point.

Chiang YJ, Calado RT, Hathcock KS, Lansdorp PM, Young NS, Hodes RJ.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10148-53. doi: 10.1073/pnas.0913125107. Epub 2010 May 17.

13.

A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome.

Ueda Y, Calado RT, Norberg A, Kajigaya S, Roos G, Hellstrom-Lindberg E, Young NS.

BMC Med Genet. 2014 Jun 19;15:68. doi: 10.1186/1471-2350-15-68.

14.

Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure.

Vulliamy TJ, Walne A, Baskaradas A, Mason PJ, Marrone A, Dokal I.

Blood Cells Mol Dis. 2005 May-Jun;34(3):257-63.

PMID:
15885610
15.

Telomeres and marrow failure.

Calado RT.

Hematology Am Soc Hematol Educ Program. 2009:338-43. doi: 10.1182/asheducation-2009.1.338. Review.

PMID:
20008219
16.

Telomere length variation and telomerase activity expression in patients with congenital and acquired aplastic anemia.

Polychronopoulou S, Koutroumba P.

Acta Haematol. 2004;111(3):125-31. Review.

PMID:
15034232
17.

Arm-specific telomere dynamics of each individual chromosome in induced pluripotent stem cells revealed by quantitative fluorescence in situ hybridization.

Terai M, Izumiyama-Shimomura N, Aida J, Ishikawa N, Kuroiwa M, Arai T, Toyoda M, Nakamura K, Takubo K.

Tissue Cell. 2014 Dec;46(6):470-6. doi: 10.1016/j.tice.2014.08.005. Epub 2014 Aug 27.

PMID:
25217290
18.

Efficient commitment to functional CD34+ progenitor cells from human bone marrow mesenchymal stem-cell-derived induced pluripotent stem cells.

Xu Y, Liu L, Zhang L, Fu S, Hu Y, Wang Y, Fu H, Wu K, Xiao H, Liu S, Yu X, Zheng W, Feng B, Huang H.

PLoS One. 2012;7(4):e34321. doi: 10.1371/journal.pone.0034321. Epub 2012 Apr 9. Erratum in: PLoS One. 2012;7(8). doi:10.1371/annotation/ebddb7ce-712c-4f9d-8412-20dc827c30b9.

19.

Telomerase reverse transcriptase-dependent telomere equilibration mitigates tissue dysfunction in mTert heterozygotes.

Meznikova M, Erdmann N, Allsopp R, Harrington LA.

Dis Model Mech. 2009 Nov-Dec;2(11-12):620-6. doi: 10.1242/dmm.004069. Epub 2009 Oct 19.

20.

Erosion of telomeric single-stranded overhang in patients with aplastic anaemia carrying telomerase complex mutations.

Calado RT, Regal JA, Kajigaya S, Young NS.

Eur J Clin Invest. 2009 Nov;39(11):1025-32. doi: 10.1111/j.1365-2362.2009.02209.x. Epub 2009 Aug 11.

PMID:
19674077
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