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Results: 1 to 20 of 101

1.

Possible involvement of LKB1-AMPK signaling in non-homologous end joining.

Ui A, Ogiwara H, Nakajima S, Kanno S, Watanabe R, Harata M, Okayama H, Harris CC, Yokota J, Yasui A, Kohno T.

Oncogene. 2014 Mar 27;33(13):1640-8. doi: 10.1038/onc.2013.125. Epub 2013 Apr 15.

PMID:
23584481
[PubMed - indexed for MEDLINE]
2.

Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors.

Ogiwara H, Ui A, Otsuka A, Satoh H, Yokomi I, Nakajima S, Yasui A, Yokota J, Kohno T.

Oncogene. 2011 May 5;30(18):2135-46. doi: 10.1038/onc.2010.592;. Epub 2011 Jan 10.

PMID:
21217779
[PubMed - indexed for MEDLINE]
3.

Mechanisms of DNA double strand break repair and chromosome aberration formation.

Iliakis G, Wang H, Perrault AR, Boecker W, Rosidi B, Windhofer F, Wu W, Guan J, Terzoudi G, Pantelias G.

Cytogenet Genome Res. 2004;104(1-4):14-20. Review.

PMID:
15162010
[PubMed - indexed for MEDLINE]
4.

Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity.

Forcet C, Etienne-Manneville S, Gaude H, Fournier L, Debilly S, Salmi M, Baas A, Olschwang S, Clevers H, Billaud M.

Hum Mol Genet. 2005 May 15;14(10):1283-92. Epub 2005 Mar 30.

PMID:
15800014
[PubMed - indexed for MEDLINE]
Free Article
5.

Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining.

Helfricht A, Wiegant WW, Thijssen PE, Vertegaal AC, Luijsterburg MS, van Attikum H.

Cell Cycle. 2013 Sep 15;12(18):3070-82. doi: 10.4161/cc.26033. Epub 2013 Aug 20.

PMID:
23974106
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Biochemical evidence for Ku-independent backup pathways of NHEJ.

Wang H, Perrault AR, Takeda Y, Qin W, Wang H, Iliakis G.

Nucleic Acids Res. 2003 Sep 15;31(18):5377-88.

PMID:
12954774
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells.

Delacôte F, Han M, Stamato TD, Jasin M, Lopez BS.

Nucleic Acids Res. 2002 Aug 1;30(15):3454-63.

PMID:
12140331
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The impact of heterochromatin on DSB repair.

Goodarzi AA, Noon AT, Jeggo PA.

Biochem Soc Trans. 2009 Jun;37(Pt 3):569-76. doi: 10.1042/BST0370569.

PMID:
19442252
[PubMed - indexed for MEDLINE]
9.

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, Alessi DR, Hardie DG.

J Biol. 2003;2(4):28. Epub 2003 Sep 24.

PMID:
14511394
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis.

Nagalingam A, Arbiser JL, Bonner MY, Saxena NK, Sharma D.

Breast Cancer Res. 2012 Feb 21;14(1):R35.

PMID:
22353783
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax.

Goodarzi AA, Jeggo P, Lobrich M.

DNA Repair (Amst). 2010 Dec 10;9(12):1273-82. doi: 10.1016/j.dnarep.2010.09.013. Epub 2010 Oct 30. Review.

PMID:
21036673
[PubMed - indexed for MEDLINE]
12.

Regulation of DNA double-strand break repair pathway choice.

Shrivastav M, De Haro LP, Nickoloff JA.

Cell Res. 2008 Jan;18(1):134-47. Review.

PMID:
18157161
[PubMed - indexed for MEDLINE]
Free Article
13.

Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis.

Tanwar PS, Kaneko-Tarui T, Zhang L, Teixeira JM.

Hum Mol Genet. 2012 Oct 15;21(20):4394-405. Epub 2012 Jul 12.

PMID:
22791749
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner.

Suzuki A, Kusakai G, Kishimoto A, Shimojo Y, Ogura T, Lavin MF, Esumi H.

Biochem Biophys Res Commun. 2004 Nov 19;324(3):986-92.

PMID:
15485651
[PubMed - indexed for MEDLINE]
15.

SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells.

Zu Y, Liu L, Lee MY, Xu C, Liang Y, Man RY, Vanhoutte PM, Wang Y.

Circ Res. 2010 Apr 30;106(8):1384-93. doi: 10.1161/CIRCRESAHA.109.215483. Epub 2010 Mar 4.

PMID:
20203304
[PubMed - indexed for MEDLINE]
Free Article
16.

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.

Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3329-35. Epub 2004 Feb 25.

PMID:
14985505
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation.

Jaleel M, Villa F, Deak M, Toth R, Prescott AR, Van Aalten DM, Alessi DR.

Biochem J. 2006 Mar 15;394(Pt 3):545-55.

PMID:
16396636
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells.

Wang H, Zeng ZC, Perrault AR, Cheng X, Qin W, Iliakis G.

Nucleic Acids Res. 2001 Apr 15;29(8):1653-60.

PMID:
11292837
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Double strand break repair by homologous recombination is regulated by cell cycle-independent signaling via ATM in human glioma cells.

Golding SE, Rosenberg E, Khalil A, McEwen A, Holmes M, Neill S, Povirk LF, Valerie K.

J Biol Chem. 2004 Apr 9;279(15):15402-10. Epub 2004 Jan 26. Erratum in: J Biol Chem. 2004 Jun 4;279(23):24906.

PMID:
14744854
[PubMed - indexed for MEDLINE]
Free Article
20.

LKB1-AMPK axis revisited.

Kottakis F, Bardeesy N.

Cell Res. 2012 Dec;22(12):1617-20. doi: 10.1038/cr.2012.108. Epub 2012 Jul 17.

PMID:
22801477
[PubMed - indexed for MEDLINE]
Free PMC Article

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