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Results: 1 to 20 of 115

1.

Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.

Zhang W, Zhang Y, Wang W, Dai Y, Ning C, Luo R, Sun K, Glover L, Grenz A, Sun H, Tao L, Zhang W, Colgan SP, Blackburn MR, Eltzschig HK, Kellems RE, Xia Y.

Circ Res. 2013 May 24;112(11):1466-78. doi: 10.1161/CIRCRESAHA.111.300166. Epub 2013 Apr 12.

PMID:
23584256
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

CD73-dependent generation of adenosine and endothelial Adora2b signaling attenuate diabetic nephropathy.

Tak E, Ridyard D, Kim JH, Zimmerman M, Werner T, Wang XX, Shabeka U, Seo SW, Christians U, Klawitter J, Moldovan R, Garcia G, Levi M, Haase V, Ravid K, Eltzschig HK, Grenz A.

J Am Soc Nephrol. 2014 Mar;25(3):547-63. doi: 10.1681/ASN.2012101014. Epub 2013 Nov 21.

PMID:
24262796
[PubMed - indexed for MEDLINE]
3.

Interleukin 6 underlies angiotensin II-induced hypertension and chronic renal damage.

Zhang W, Wang W, Yu H, Zhang Y, Dai Y, Ning C, Tao L, Sun H, Kellems RE, Blackburn MR, Xia Y.

Hypertension. 2012 Jan;59(1):136-44. doi: 10.1161/HYPERTENSIONAHA.111.173328. Epub 2011 Nov 7.

PMID:
22068875
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A2B adenosine receptor contributes to penile erection via PI3K/AKT signaling cascade-mediated eNOS activation.

Wen J, Grenz A, Zhang Y, Dai Y, Kellems RE, Blackburn MR, Eltzschig HK, Xia Y.

FASEB J. 2011 Aug;25(8):2823-30. doi: 10.1096/fj.11-181057. Epub 2011 May 12.

PMID:
21566208
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Hypoxia-inducible factor-1α-dependent protection from intestinal ischemia/reperfusion injury involves ecto-5'-nucleotidase (CD73) and the A2B adenosine receptor.

Hart ML, Grenz A, Gorzolla IC, Schittenhelm J, Dalton JH, Eltzschig HK.

J Immunol. 2011 Apr 1;186(7):4367-74. doi: 10.4049/jimmunol.0903617. Epub 2011 Feb 28.

PMID:
21357264
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Chronic kidney disease: Renal adenosine in hypertensive CKD.

Carney EF.

Nat Rev Nephrol. 2013 Jun;9(6):309. doi: 10.1038/nrneph.2013.70. Epub 2013 Apr 30. No abstract available.

PMID:
23629639
[PubMed - indexed for MEDLINE]
7.

Ecto-5'-nucleotidase, CD73, is an endothelium-derived hyperpolarizing factor synthase.

Ohta M, Toyama K, Gutterman DD, Campbell WB, Lemaître V, Teraoka R, Miura H.

Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):629-36. doi: 10.1161/ATVBAHA.112.300600. Epub 2013 Jan 3.

PMID:
23288168
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Protective role of ecto-5'-nucleotidase (CD73) in renal ischemia.

Grenz A, Zhang H, Eckle T, Mittelbronn M, Wehrmann M, Köhle C, Kloor D, Thompson LF, Osswald H, Eltzschig HK.

J Am Soc Nephrol. 2007 Mar;18(3):833-45. Epub 2007 Jan 31.

PMID:
17267736
[PubMed - indexed for MEDLINE]
Free Article
9.

Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors.

Eckle T, Krahn T, Grenz A, Köhler D, Mittelbronn M, Ledent C, Jacobson MA, Osswald H, Thompson LF, Unertl K, Eltzschig HK.

Circulation. 2007 Mar 27;115(12):1581-90. Epub 2007 Mar 12.

PMID:
17353435
[PubMed - indexed for MEDLINE]
Free Article
10.

Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury.

Eckle T, Hughes K, Ehrentraut H, Brodsky KS, Rosenberger P, Choi DS, Ravid K, Weng T, Xia Y, Blackburn MR, Eltzschig HK.

FASEB J. 2013 Aug;27(8):3078-89. doi: 10.1096/fj.13-228551. Epub 2013 Apr 19.

PMID:
23603835
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

CD73-generated adenosine promotes osteoblast differentiation.

Takedachi M, Oohara H, Smith BJ, Iyama M, Kobashi M, Maeda K, Long CL, Humphrey MB, Stoecker BJ, Toyosawa S, Thompson LF, Murakami S.

J Cell Physiol. 2012 Jun;227(6):2622-31. doi: 10.1002/jcp.23001.

PMID:
21882189
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Extracellular purine metabolism and signaling of CD73-derived adenosine in murine Treg and Teff cells.

Romio M, Reinbeck B, Bongardt S, Hüls S, Burghoff S, Schrader J.

Am J Physiol Cell Physiol. 2011 Aug;301(2):C530-9. doi: 10.1152/ajpcell.00385.2010. Epub 2011 May 18.

PMID:
21593451
[PubMed - indexed for MEDLINE]
Free Article
13.

The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury.

Kim M, Ham A, Kim JY, Brown KM, D'Agati VD, Lee HT.

Kidney Int. 2013 Jul;84(1):90-103. doi: 10.1038/ki.2013.43. Epub 2013 Feb 20.

PMID:
23423261
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The stimulatory adenosine receptor ADORA2B regulates serotonin (5-HT) synthesis and release in oxygen-depleted EC cells in inflammatory bowel disease.

Damen R, Haugen M, Svejda B, Alaimo D, Brenna O, Pfragner R, Gustafsson BI, Kidd M.

PLoS One. 2013 Apr 26;8(4):e62607. doi: 10.1371/journal.pone.0062607. Print 2013.

PMID:
23638125
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Role of extracellular nucleotide phosphohydrolysis in intestinal ischemia-reperfusion injury.

Hart ML, Henn M, Köhler D, Kloor D, Mittelbronn M, Gorzolla IC, Stahl GL, Eltzschig HK.

FASEB J. 2008 Aug;22(8):2784-97. doi: 10.1096/fj.07-103911. Epub 2008 Mar 19.

PMID:
18353866
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Identification of hypoxia-inducible factor HIF-1A as transcriptional regulator of the A2B adenosine receptor during acute lung injury.

Eckle T, Kewley EM, Brodsky KS, Tak E, Bonney S, Gobel M, Anderson D, Glover LE, Riegel AK, Colgan SP, Eltzschig HK.

J Immunol. 2014 Feb 1;192(3):1249-56. doi: 10.4049/jimmunol.1100593. Epub 2014 Jan 3.

PMID:
24391213
[PubMed - indexed for MEDLINE]
17.

A2B adenosine receptor-mediated induction of IL-6 promotes CKD.

Dai Y, Zhang W, Wen J, Zhang Y, Kellems RE, Xia Y.

J Am Soc Nephrol. 2011 May;22(5):890-901. doi: 10.1681/ASN.2010080890. Epub 2011 Apr 21.

PMID:
21511827
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Adora2b adenosine receptor signaling protects during acute kidney injury via inhibition of neutrophil-dependent TNF-α release.

Grenz A, Kim JH, Bauerle JD, Tak E, Eltzschig HK, Clambey ET.

J Immunol. 2012 Nov 1;189(9):4566-73. doi: 10.4049/jimmunol.1201651. Epub 2012 Oct 1.

PMID:
23028059
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes.

Takedachi M, Qu D, Ebisuno Y, Oohara H, Joachims ML, McGee ST, Maeda E, McEver RP, Tanaka T, Miyasaka M, Murakami S, Krahn T, Blackburn MR, Thompson LF.

J Immunol. 2008 May 1;180(9):6288-96.

PMID:
18424752
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Signaling through hepatocellular A2B adenosine receptors dampens ischemia and reperfusion injury of the liver.

Zimmerman MA, Grenz A, Tak E, Kaplan M, Ridyard D, Brodsky KS, Mandell MS, Kam I, Eltzschig HK.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12012-7. doi: 10.1073/pnas.1221733110. Epub 2013 Jun 28.

PMID:
23812746
[PubMed - indexed for MEDLINE]
Free PMC Article

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