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1.

Direct Renin inhibitor: aliskiren in chronic kidney disease.

Morishita Y, Kusano E.

Nephrourol Mon. 2013 Winter;5(1):668-72. doi: 10.5812/numonthly.3679. Epub 2012 Dec 15.

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Effects of aliskiren on blood pressure and the predictive biomarkers for cardiovascular disease in hemodialysis-dependent chronic kidney disease patients with hypertension.

Morishita Y, Hanawa S, Chinda J, Iimura O, Tsunematsu S, Kusano E.

Hypertens Res. 2011 Mar;34(3):308-13. doi: 10.1038/hr.2010.238. Epub 2010 Dec 2.

PMID:
21124333
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5.

[Direct renin inhibitor aliskiren in the treatment of cardiovascular and renal diseases].

Horký K.

Vnitr Lek. 2010 Feb;56(2):120-6. Review. Czech.

PMID:
20329582
6.

Is there a future for direct renin inhibitors?

Chaudhary K, Nistala R, Whaley-Connell A.

Expert Opin Investig Drugs. 2010 May;19(5):653-61. doi: 10.1517/13543781003781906. Review.

PMID:
20380486
7.

Inhibition of the renin angiotensin aldosterone system: focus on aliskiren.

Rao MS.

J Assoc Physicians India. 2010 Feb;58:102-8. Review.

PMID:
20653151
8.

Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading.

Yoshida S, Ishizawa K, Ayuzawa N, Ueda K, Takeuchi M, Kawarazaki W, Fujita T, Nagase M.

Clin Exp Nephrol. 2014 Aug;18(4):593-9. doi: 10.1007/s10157-013-0893-6. Epub 2013 Oct 24.

PMID:
24154707
9.

New insights into the renoprotective actions of the renin inhibitor aliskiren in experimental renal disease.

Feldman DL.

Hypertens Res. 2010 Apr;33(4):279-87. doi: 10.1038/hr.2010.19. Epub 2010 Mar 5. Review.

PMID:
20203685
10.

Aliskiren suppresses the renin-angiotensin-aldosterone system and reduces blood pressure and albuminuria in elderly chronic kidney disease patients with hypertension.

Morishita Y, Yasui T, Numata A, Onishi A, Ishibashi K, Kusano E.

Int J Nephrol Renovasc Dis. 2012;5:125-33. doi: 10.2147/IJNRD.S36451. Epub 2012 Sep 21.

11.

Current strategies to achieve further cardiac and renal protection through enhanced renin-angiotensin-aldosterone system inhibition.

Alfie J, Aparicio LS, Waisman GD.

Rev Recent Clin Trials. 2011 May;6(2):134-46. Review.

PMID:
21241234
12.

Aliskiren, a direct renin inhibitor, in clinical practice: a new approach in the treatment of hypertension.

Moutzouri E, Florentin M, Elisaf MS, Mikhailidis DP, Liberopoulos EN.

Curr Vasc Pharmacol. 2010 May;8(3):344-62. Review.

PMID:
20180771
13.

Optimal antagonism of the Renin-Angiotensin-aldosterone system: do we need dual or triple therapy?

Werner C, Pöss J, Böhm M.

Drugs. 2010 Jul 9;70(10):1215-30. doi: 10.2165/11537910-000000000-00000. Review.

PMID:
20568830
14.

New therapeutic options in patients prone to hypertension: a focus on direct Renin inhibition and aldosterone blockade.

Basile J.

Am J Med Sci. 2009 Jun;337(6):438-44. doi: 10.1097/MAJ.0b013e31819b3a80. Review.

PMID:
19390429
15.

Clinical role of direct renin inhibition in hypertension.

Taylor AA, Pool JL.

Am J Ther. 2012 May;19(3):204-10. doi: 10.1097/MJT.0b013e3182068da5.

PMID:
21317620
16.

Aliskiren in the treatment of hypertension and organ damage.

Riccioni G.

Cardiovasc Ther. 2011 Feb;29(1):77-87. doi: 10.1111/j.1755-5922.2010.00230.x. Epub 2010 Nov 25. Review.

PMID:
21106033
17.

Dual blockade of the renin-angiotensin-aldosterone system: beyond the ACE inhibitor and angiotensin-II receptor blocker combination.

Bomback AS, Toto R.

Am J Hypertens. 2009 Oct;22(10):1032-40. doi: 10.1038/ajh.2009.138. Epub 2009 Aug 6. Review.

PMID:
19661925
18.

The biochemical pharmacology of renin inhibitors: implications for translational medicine in hypertension, diabetic nephropathy and heart failure: expectations and reality.

Abassi Z, Winaver J, Feuerstein GZ.

Biochem Pharmacol. 2009 Oct 15;78(8):933-40. doi: 10.1016/j.bcp.2009.05.018. Epub 2009 May 27. Review.

PMID:
19477166
19.

Aliskiren as a novel therapeutic agent for hypertension and cardio-renal diseases.

Rashikh A, Ahmad SJ, Pillai KK, Najmi AK.

J Pharm Pharmacol. 2012 Apr;64(4):470-81. doi: 10.1111/j.2042-7158.2011.01414.x. Epub 2011 Dec 7. Review.

PMID:
22420653
20.

The renin inhibitor aliskiren as novel treatment for cardiovascular disease.

Saez AO, Philipp T, Nürnberger J.

Recent Pat Cardiovasc Drug Discov. 2006 Nov;1(3):233-40. Review.

PMID:
18221088
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