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Items: 1 to 20 of 125

1.

Arterial klotho expression and FGF23 effects on vascular calcification and function.

Lindberg K, Olauson H, Amin R, Ponnusamy A, Goetz R, Taylor RF, Mohammadi M, Canfield A, Kublickiene K, Larsson TE.

PLoS One. 2013;8(4):e60658. doi: 10.1371/journal.pone.0060658. Epub 2013 Apr 5.

2.

Fibroblast growth factor 23 accelerates phosphate-induced vascular calcification in the absence of Klotho deficiency.

Jimbo R, Kawakami-Mori F, Mu S, Hirohama D, Majtan B, Shimizu Y, Yatomi Y, Fukumoto S, Fujita T, Shimosawa T.

Kidney Int. 2014 May;85(5):1103-11. doi: 10.1038/ki.2013.332. Epub 2013 Oct 2.

PMID:
24088960
3.

Targeted deletion of Klotho in kidney distal tubule disrupts mineral metabolism.

Olauson H, Lindberg K, Amin R, Jia T, Wernerson A, Andersson G, Larsson TE.

J Am Soc Nephrol. 2012 Oct;23(10):1641-51. Epub 2012 Aug 9.

4.

Stanniocalcin 2 is associated with ectopic calcification in α-klotho mutant mice and inhibits hyperphosphatemia-induced calcification in aortic vascular smooth muscle cells.

Takei Y, Yamamoto H, Sato T, Otani A, Kozai M, Masuda M, Taketani Y, Muto-Sato K, Lanske B, Takeda E.

Bone. 2012 Apr;50(4):998-1005. doi: 10.1016/j.bone.2012.01.006. Epub 2012 Jan 21.

PMID:
22285620
5.

Klotho ablation converts the biochemical and skeletal alterations in FGF23 (R176Q) transgenic mice to a Klotho-deficient phenotype.

Bai X, Dinghong Q, Miao D, Goltzman D, Karaplis AC.

Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E79-88. doi: 10.1152/ajpendo.90539.2008. Epub 2008 Nov 4.

6.

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis.

Nakatani T, Sarraj B, Ohnishi M, Densmore MJ, Taguchi T, Goetz R, Mohammadi M, Lanske B, Razzaque MS.

FASEB J. 2009 Feb;23(2):433-41. doi: 10.1096/fj.08-114397. Epub 2008 Oct 3.

7.

Parathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion.

Olauson H, Lindberg K, Amin R, Sato T, Jia T, Goetz R, Mohammadi M, Andersson G, Lanske B, Larsson TE.

PLoS Genet. 2013;9(12):e1003975. doi: 10.1371/journal.pgen.1003975. Epub 2013 Dec 12.

8.

Klotho deficiency causes vascular calcification in chronic kidney disease.

Hu MC, Shi M, Zhang J, Quiñones H, Griffith C, Kuro-o M, Moe OW.

J Am Soc Nephrol. 2011 Jan;22(1):124-36. doi: 10.1681/ASN.2009121311. Epub 2010 Nov 29.

9.

Reduced renal α-Klotho expression in CKD patients and its effect on renal phosphate handling and vitamin D metabolism.

Sakan H, Nakatani K, Asai O, Imura A, Tanaka T, Yoshimoto S, Iwamoto N, Kurumatani N, Iwano M, Nabeshima Y, Konishi N, Saito Y.

PLoS One. 2014 Jan 23;9(1):e86301. doi: 10.1371/journal.pone.0086301. eCollection 2014.

10.

Deletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- mice.

Yuan Q, Sato T, Densmore M, Saito H, Schüler C, Erben RG, Lanske B.

PLoS Genet. 2012;8(5):e1002726. doi: 10.1371/journal.pgen.1002726. Epub 2012 May 17.

11.

Direct, acute effects of Klotho and FGF23 on vascular smooth muscle and endothelium.

Six I, Okazaki H, Gross P, Cagnard J, Boudot C, Maizel J, Drueke TB, Massy ZA.

PLoS One. 2014 Apr 2;9(4):e93423. doi: 10.1371/journal.pone.0093423. eCollection 2014.

12.

New insights into the FGF23-Klotho axis.

Olauson H, Vervloet MG, Cozzolino M, Massy ZA, Ureña Torres P, Larsson TE.

Semin Nephrol. 2014 Nov;34(6):586-97. doi: 10.1016/j.semnephrol.2014.09.005. Review.

PMID:
25498378
13.

Does Fgf23-klotho activity influence vascular and soft tissue calcification through regulating mineral ion metabolism?

Memon F, El-Abbadi M, Nakatani T, Taguchi T, Lanske B, Razzaque MS.

Kidney Int. 2008 Sep;74(5):566-70. doi: 10.1038/ki.2008.218. Epub 2008 Jun 4. Review.

14.

[Updates on rickets and osteomalacia: various roles of Klotho and FGF23 in vivo ].

Imura A.

Clin Calcium. 2013 Oct;23(10):1476-82. doi: CliCa131014761482. Review. Japanese.

PMID:
24076646
15.

Klotho converts canonical FGF receptor into a specific receptor for FGF23.

Urakawa I, Yamazaki Y, Shimada T, Iijima K, Hasegawa H, Okawa K, Fujita T, Fukumoto S, Yamashita T.

Nature. 2006 Dec 7;444(7120):770-4. Epub 2006 Oct 29.

PMID:
17086194
16.

Fibroblast growth factor 23 is not associated with and does not induce arterial calcification.

Scialla JJ, Lau WL, Reilly MP, Isakova T, Yang HY, Crouthamel MH, Chavkin NW, Rahman M, Wahl P, Amaral AP, Hamano T, Master SR, Nessel L, Chai B, Xie D, Kallem RR, Chen J, Lash JP, Kusek JW, Budoff MJ, Giachelli CM, Wolf M; Chronic Renal Insufficiency Cohort Study Investigators.

Kidney Int. 2013 Jun;83(6):1159-68. doi: 10.1038/ki.2013.3. Epub 2013 Feb 6.

17.

Altered renal FGF23-mediated activity involving MAPK and Wnt: effects of the Hyp mutation.

Farrow EG, Summers LJ, Schiavi SC, McCormick JA, Ellison DH, White KE.

J Endocrinol. 2010 Oct;207(1):67-75. doi: 10.1677/JOE-10-0181. Epub 2010 Jul 30.

18.

Fibroblast growth factor 23 and Klotho are present in the growth plate.

Raimann A, Ertl DA, Helmreich M, Sagmeister S, Egerbacher M, Haeusler G.

Connect Tissue Res. 2013;54(2):108-17. doi: 10.3109/03008207.2012.753879. Epub 2013 Jan 18.

PMID:
23206185
19.

Fibroblast growth factor 23 (FGF23) and alpha-klotho stimulate osteoblastic MC3T3.E1 cell proliferation and inhibit mineralization.

Shalhoub V, Ward SC, Sun B, Stevens J, Renshaw L, Hawkins N, Richards WG.

Calcif Tissue Int. 2011 Aug;89(2):140-50. doi: 10.1007/s00223-011-9501-5. Epub 2011 Jun 3.

20.

[Vascular Calcification - Pathological Mechanism and Clinical Application - . Vascular calcification in klotho deficient environment].

Hasegawa T, Yamamoto T, Hongo H, Tsuboi K, Amizuka N.

Clin Calcium. 2015 May;25(5):693-9. doi: CliCa1505693699. Review. Japanese.

PMID:
25926573
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