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Results: 1 to 20 of 108

1.

Lyophilization of a triply unsaturated phospholipid: effects of trace metal contaminants.

Payton NM, Wempe MF, Betker JL, Randolph TW, Anchordoquy TJ.

Eur J Pharm Biopharm. 2013 Oct;85(2):306-13. doi: 10.1016/j.ejpb.2013.03.028. Epub 2013 Apr 6.

PMID:
23567484
[PubMed - indexed for MEDLINE]
2.

Development of lyophilized gemini surfactant-based gene delivery systems: influence of lyophilization on the structure, activity and stability of the lipoplexes.

Mohammed-Saeid W, Michel D, El-Aneed A, Verrall RE, Low NH, Badea I.

J Pharm Pharm Sci. 2012;15(4):548-67.

PMID:
23106958
[PubMed - indexed for MEDLINE]
Free Article
3.

Effect of lyophilization and freeze-thawing on the stability of siRNA-liposome complexes.

Yadava P, Gibbs M, Castro C, Hughes JA.

AAPS PharmSciTech. 2008;9(2):335-41. doi: 10.1208/s12249-007-9000-1. Epub 2007 Dec 29.

PMID:
18431646
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Effect of buffer systems and disaccharides concentration on Podoviridae coliphage stability during freeze drying and storage.

Dini C, de Urraza PJ.

Cryobiology. 2013 Jun;66(3):339-42. doi: 10.1016/j.cryobiol.2013.03.007. Epub 2013 Mar 26.

PMID:
23537872
[PubMed - indexed for MEDLINE]
5.

Metal contaminants promote degradation of lipid/DNA complexes during lyophilization.

Molina Md, Anchordoquy TJ.

Biochim Biophys Acta. 2007 Mar;1768(3):669-77. Epub 2006 Dec 8.

PMID:
17224131
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Effect of cryoprotectants on freezing, lyophilization, and storage of lyophilized recombinant alpha 1-antitrypsin formulations.

Vemuri S, Yu CD, Roosdorp N.

PDA J Pharm Sci Technol. 1994 Sep-Oct;48(5):241-6.

PMID:
8000898
[PubMed - indexed for MEDLINE]
7.
8.

Lyophilization of cholesterol-free PEGylated liposomes and its impact on drug loading by passive equilibration.

Chaudhury A, Das S, Lee RF, Tan KB, Ng WK, Tan RB, Chiu GN.

Int J Pharm. 2012 Jul 1;430(1-2):167-75. doi: 10.1016/j.ijpharm.2012.04.036. Epub 2012 Apr 16.

PMID:
22537806
[PubMed - indexed for MEDLINE]
9.
10.

A specific molar ratio of stabilizer to protein is required for storage stability of a lyophilized monoclonal antibody.

Cleland JL, Lam X, Kendrick B, Yang J, Yang TH, Overcashier D, Brooks D, Hsu C, Carpenter JF.

J Pharm Sci. 2001 Mar;90(3):310-21.

PMID:
11170024
[PubMed - indexed for MEDLINE]
11.

Lyophilization-induced protein denaturation in phosphate buffer systems: monomeric and tetrameric beta-galactosidase.

Pikal-Cleland KA, Carpenter JF.

J Pharm Sci. 2001 Sep;90(9):1255-68.

PMID:
11745778
[PubMed - indexed for MEDLINE]
12.

Lyophilization of cationic lipid-protamine-DNA (LPD) complexes.

Li B, Li S, Tan Y, Stolz DB, Watkins SC, Block LH, Huang L.

J Pharm Sci. 2000 Mar;89(3):355-64.

PMID:
10707016
[PubMed - indexed for MEDLINE]
13.

Formulation kit for liposomal doxorubicin composed of lyophilized liposomes.

Stevens PJ, Lee RJ.

Anticancer Res. 2003 Jan-Feb;23(1A):439-42.

PMID:
12680245
[PubMed - indexed for MEDLINE]
14.

Long-term stability of sterically stabilized liposomes by freezing and freeze-drying: Effects of cryoprotectants on structure.

Stark B, Pabst G, Prassl R.

Eur J Pharm Sci. 2010 Nov 20;41(3-4):546-55. doi: 10.1016/j.ejps.2010.08.010. Epub 2010 Aug 26.

PMID:
20800680
[PubMed - indexed for MEDLINE]
15.

Effect of controlled ice nucleation on primary drying stage and protein recovery in vials cooled in a modified freeze-dryer.

Passot S, Tréléa IC, Marin M, Galan M, Morris GJ, Fonseca F.

J Biomech Eng. 2009 Jul;131(7):074511. doi: 10.1115/1.3143034.

PMID:
19640147
[PubMed - indexed for MEDLINE]
16.

Degradation of lyophilized lipid/DNA complexes during storage: the role of lipid and reactive oxygen species.

Molina MD, Anchordoquy TJ.

Biochim Biophys Acta. 2008 Oct;1778(10):2119-26. doi: 10.1016/j.bbamem.2008.04.003. Epub 2008 Apr 10.

PMID:
18445474
[PubMed - indexed for MEDLINE]
Free Article
17.

Gap-freezing approach for shortening the lyophilization cycle time of pharmaceutical formulations-demonstration of the concept.

Kuu WY, Doty MJ, Rebbeck CL, Hurst WS, Cho YK.

J Pharm Sci. 2013 Aug;102(8):2572-88. doi: 10.1002/jps.23610. Epub 2013 May 31.

PMID:
23728733
[PubMed - indexed for MEDLINE]
18.

Optimization of the lyophilization process for long-term stability of solid-lipid nanoparticles.

Howard MD, Lu X, Jay M, Dziubla TD.

Drug Dev Ind Pharm. 2012 Oct;38(10):1270-9. doi: 10.3109/03639045.2011.645835. Epub 2012 Jan 12.

PMID:
22235767
[PubMed - indexed for MEDLINE]
19.
20.

Stabilization of lipid/DNA complexes during the freezing step of the lyophilization process: the particle isolation hypothesis.

Allison SD, Molina MC, Anchordoquy TJ.

Biochim Biophys Acta. 2000 Sep 29;1468(1-2):127-38.

PMID:
11018658
[PubMed - indexed for MEDLINE]
Free Article

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