Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 110

1.

Neuronal forms of Gaucher disease.

Vitner EB, Futerman AH.

Handb Exp Pharmacol. 2013;(216):405-19. doi: 10.1007/978-3-7091-1511-4_20. Review.

PMID:
23563668
[PubMed - indexed for MEDLINE]
2.

Phosphatidylcholine synthesis is elevated in neuronal models of Gaucher disease due to direct activation of CTP:phosphocholine cytidylyltransferase by glucosylceramide.

Bodennec J, Pelled D, Riebeling C, Trajkovic S, Futerman AH.

FASEB J. 2002 Nov;16(13):1814-6. Epub 2002 Sep 5.

PMID:
12223447
[PubMed - indexed for MEDLINE]
Free Article
3.

Enhanced calcium release in the acute neuronopathic form of Gaucher disease.

Pelled D, Trajkovic-Bodennec S, Lloyd-Evans E, Sidransky E, Schiffmann R, Futerman AH.

Neurobiol Dis. 2005 Feb;18(1):83-8.

PMID:
15649698
[PubMed - indexed for MEDLINE]
4.

Gaucher disease: pathological mechanisms and modern management.

Jmoudiak M, Futerman AH.

Br J Haematol. 2005 Apr;129(2):178-88. Review.

PMID:
15813845
[PubMed - indexed for MEDLINE]
5.

Spatial and temporal correlation between neuron loss and neuroinflammation in a mouse model of neuronopathic Gaucher disease.

Farfel-Becker T, Vitner EB, Pressey SN, Eilam R, Cooper JD, Futerman AH.

Hum Mol Genet. 2011 Apr 1;20(7):1375-86. doi: 10.1093/hmg/ddr019. Epub 2011 Jan 20.

PMID:
21252206
[PubMed - indexed for MEDLINE]
Free Article
6.

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies.

Mazzulli JR, Xu YH, Sun Y, Knight AL, McLean PJ, Caldwell GA, Sidransky E, Grabowski GA, Krainc D.

Cell. 2011 Jul 8;146(1):37-52. doi: 10.1016/j.cell.2011.06.001. Epub 2011 Jun 23.

PMID:
21700325
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Downregulation of neurotrophic factors in the brain of a mouse model of Gaucher disease; implications for neuronal loss in Gaucher disease.

Kim EY, Hong YB, Go SH, Lee B, Jung SC.

Exp Mol Med. 2006 Aug 31;38(4):348-56.

PMID:
16953113
[PubMed - indexed for MEDLINE]
Free Article
9.

In vitro accumulation of glucocerebroside in neuroblastoma cells: a model for study of Gaucher disease pathobiology.

Prence EM, Chaturvedi P, Newburg DS.

J Neurosci Res. 1996 Feb 1;43(3):365-71.

PMID:
8714525
[PubMed - indexed for MEDLINE]
10.

A biochemical and ultrastructural evaluation of the type 2 Gaucher mouse.

Willemsen R, Tybulewicz V, Sidransky E, Eliason WK, Martin BM, LaMarca ME, Reuser AJ, Tremblay M, Westphal H, Mulligan RC, et al.

Mol Chem Neuropathol. 1995 Feb-Apr;24(2-3):179-92.

PMID:
7632321
[PubMed - indexed for MEDLINE]
11.

Elevation of intracellular glucosylceramide levels results in an increase in endoplasmic reticulum density and in functional calcium stores in cultured neurons.

Korkotian E, Schwarz A, Pelled D, Schwarzmann G, Segal M, Futerman AH.

J Biol Chem. 1999 Jul 30;274(31):21673-8.

PMID:
10419477
[PubMed - indexed for MEDLINE]
Free Article
12.

Down-regulation of Bcl-2 in the fetal brain of the Gaucher disease mouse model: a possible role in the neuronal loss.

Hong YB, Kim EY, Jung SC.

J Hum Genet. 2004;49(7):349-54. Epub 2004 Jun 4.

PMID:
15179559
[PubMed - indexed for MEDLINE]
13.

Neuronopathic Gaucher disease in the mouse: viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) mice with glucosylsphingosine and glucosylceramide accumulation and progressive neurological deficits.

Sun Y, Liou B, Ran H, Skelton MR, Williams MT, Vorhees CV, Kitatani K, Hannun YA, Witte DP, Xu YH, Grabowski GA.

Hum Mol Genet. 2010 Mar 15;19(6):1088-97. doi: 10.1093/hmg/ddp580. Epub 2010 Jan 4.

PMID:
20047948
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy of Gaucher disease.

McEachern KA, Fung J, Komarnitsky S, Siegel CS, Chuang WL, Hutto E, Shayman JA, Grabowski GA, Aerts JM, Cheng SH, Copeland DP, Marshall J.

Mol Genet Metab. 2007 Jul;91(3):259-67. Epub 2007 May 16.

PMID:
17509920
[PubMed - indexed for MEDLINE]
15.

Accumulation and distribution of α-synuclein and ubiquitin in the CNS of Gaucher disease mouse models.

Xu YH, Sun Y, Ran H, Quinn B, Witte D, Grabowski GA.

Mol Genet Metab. 2011 Apr;102(4):436-47. doi: 10.1016/j.ymgme.2010.12.014. Epub 2010 Dec 31.

PMID:
21257328
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Lysosomal storage disorders and Parkinson's disease: Gaucher disease and beyond.

Shachar T, Lo Bianco C, Recchia A, Wiessner C, Raas-Rothschild A, Futerman AH.

Mov Disord. 2011 Aug 1;26(9):1593-604. doi: 10.1002/mds.23774. Epub 2011 May 26. Review.

PMID:
21618611
[PubMed - indexed for MEDLINE]
17.

Impaired autophagosomes and lysosomes in neuronopathic Gaucher disease.

Sun Y, Grabowski GA.

Autophagy. 2010 Jul;6(5):648-9. doi: 10.4161/auto.6.5.12047. Epub 2010 Jul 1.

PMID:
20458183
[PubMed - indexed for MEDLINE]
Free Article
18.

Mitochondria and quality control defects in a mouse model of Gaucher disease--links to Parkinson's disease.

Osellame LD, Rahim AA, Hargreaves IP, Gegg ME, Richard-Londt A, Brandner S, Waddington SN, Schapira AH, Duchen MR.

Cell Metab. 2013 Jun 4;17(6):941-53. doi: 10.1016/j.cmet.2013.04.014. Epub 2013 May 23.

PMID:
23707074
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

No evidence for activation of the unfolded protein response in neuronopathic models of Gaucher disease.

Farfel-Becker T, Vitner E, Dekel H, Leshem N, Enquist IB, Karlsson S, Futerman AH.

Hum Mol Genet. 2009 Apr 15;18(8):1482-8. doi: 10.1093/hmg/ddp061. Epub 2009 Feb 3.

PMID:
19193629
[PubMed - indexed for MEDLINE]
Free Article
20.

Altered expression and distribution of cathepsins in neuronopathic forms of Gaucher disease and in other sphingolipidoses.

Vitner EB, Dekel H, Zigdon H, Shachar T, Farfel-Becker T, Eilam R, Karlsson S, Futerman AH.

Hum Mol Genet. 2010 Sep 15;19(18):3583-90. doi: 10.1093/hmg/ddq273. Epub 2010 Jul 8.

PMID:
20616152
[PubMed - indexed for MEDLINE]
Free Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk