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Lin28: primal regulator of growth and metabolism in stem cells.

Shyh-Chang N, Daley GQ.

Cell Stem Cell. 2013 Apr 4;12(4):395-406. doi: 10.1016/j.stem.2013.03.005. Review.


Identification of microRNAs regulating reprogramming factor LIN28 in embryonic stem cells and cancer cells.

Zhong X, Li N, Liang S, Huang Q, Coukos G, Zhang L.

J Biol Chem. 2010 Dec 31;285(53):41961-71. doi: 10.1074/jbc.M110.169607. Epub 2010 Oct 14.


LIN28/LIN28B: an emerging oncogenic driver in cancer stem cells.

Zhou J, Ng SB, Chng WJ.

Int J Biochem Cell Biol. 2013 May;45(5):973-8. doi: 10.1016/j.biocel.2013.02.006. Epub 2013 Feb 16. Review.


A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA.

Huang Y.

Wiley Interdiscip Rev RNA. 2012 Jul-Aug;3(4):483-94. doi: 10.1002/wrna.1112. Epub 2012 Mar 29. Review.


Aire promotes the self-renewal of embryonic stem cells through Lin28.

Bin G, Jiarong Z, Shihao W, Xiuli S, Cheng X, Liangbiao C, Ming Z.

Stem Cells Dev. 2012 Oct 10;21(15):2878-90. doi: 10.1089/scd.2012.0097. Epub 2012 Jun 11.


Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognition.

Hafner M, Max KE, Bandaru P, Morozov P, Gerstberger S, Brown M, Molina H, Tuschl T.

RNA. 2013 May;19(5):613-26. doi: 10.1261/rna.036491.112. Epub 2013 Mar 12.


How does Lin28 let-7 control development and disease?

Thornton JE, Gregory RI.

Trends Cell Biol. 2012 Sep;22(9):474-82. doi: 10.1016/j.tcb.2012.06.001. Epub 2012 Jul 9. Review.


RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation.

Närvä E, Rahkonen N, Emani MR, Lund R, Pursiheimo JP, Nästi J, Autio R, Rasool O, Denessiouk K, Lähdesmäki H, Rao A, Lahesmaa R.

Stem Cells. 2012 Mar;30(3):452-60. doi: 10.1002/stem.1013.


Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer.

Peng S, Maihle NJ, Huang Y.

Oncogene. 2010 Apr 8;29(14):2153-9. doi: 10.1038/onc.2009.500. Epub 2010 Jan 25.


Embryonic stem cell microRNAs: defining factors in induced pluripotent (iPS) and cancer (CSC) stem cells?

Gunaratne PH.

Curr Stem Cell Res Ther. 2009 Sep;4(3):168-77. Review.


Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells.

Xu B, Zhang K, Huang Y.

RNA. 2009 Mar;15(3):357-61. doi: 10.1261/rna.1368009. Epub 2009 Jan 15.


Histone H2a mRNA interacts with Lin28 and contains a Lin28-dependent posttranscriptional regulatory element.

Xu B, Huang Y.

Nucleic Acids Res. 2009 Jul;37(13):4256-63. doi: 10.1093/nar/gkp372. Epub 2009 May 13.


Metformin may antagonize Lin28 and/or Lin28B activity, thereby boosting let-7 levels and antagonizing cancer progression.

McCarty MF.

Med Hypotheses. 2012 Feb;78(2):262-9. doi: 10.1016/j.mehy.2011.10.041. Epub 2011 Nov 29.


Lin28 proteins are required for germ layer specification in Xenopus.

Faas L, Warrander FC, Maguire R, Ramsbottom SA, Quinn D, Genever P, Isaacs HV.

Development. 2013 Mar;140(5):976-86. doi: 10.1242/dev.089797. Epub 2013 Jan 23.


LIN28A is a suppressor of ER-associated translation in embryonic stem cells.

Cho J, Chang H, Kwon SC, Kim B, Kim Y, Choe J, Ha M, Kim YK, Kim VN.

Cell. 2012 Nov 9;151(4):765-77. doi: 10.1016/j.cell.2012.10.019. Epub 2012 Oct 25.


Lin28 sustains early renal progenitors and induces Wilms tumor.

Urbach A, Yermalovich A, Zhang J, Spina CS, Zhu H, Perez-Atayde AR, Shukrun R, Charlton J, Sebire N, Mifsud W, Dekel B, Pritchard-Jones K, Daley GQ.

Genes Dev. 2014 May 1;28(9):971-82. doi: 10.1101/gad.237149.113. Epub 2014 Apr 14.


Lin28 enhances tissue repair by reprogramming cellular metabolism.

Shyh-Chang N, Zhu H, Yvanka de Soysa T, Shinoda G, Seligson MT, Tsanov KM, Nguyen L, Asara JM, Cantley LC, Daley GQ.

Cell. 2013 Nov 7;155(4):778-92. doi: 10.1016/j.cell.2013.09.059.


Germline stem cells and their regulation in the nematode Caenorhabditis elegans.

Kershner A, Crittenden SL, Friend K, Sorensen EB, Porter DF, Kimble J.

Adv Exp Med Biol. 2013;786:29-46. doi: 10.1007/978-94-007-6621-1_3.


Determinants of mRNA recognition and translation regulation by Lin28.

Lei XX, Xu J, Ma W, Qiao C, Newman MA, Hammond SM, Huang Y.

Nucleic Acids Res. 2012 Apr;40(8):3574-84. doi: 10.1093/nar/gkr1279. Epub 2011 Dec 30.


The Lin28/let-7 axis regulates glucose metabolism.

Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI; DIAGRAM Consortium; MAGIC Investigators, Altshuler D, Daley GQ.

Cell. 2011 Sep 30;147(1):81-94. doi: 10.1016/j.cell.2011.08.033.

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