Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 95

1.

Exploration of Sitagliptin as a potential inhibitor for the M1 Alanine aminopeptidase enzyme in Plasmodium falciparum using computational docking.

Krishnamoorthy M, Achary A.

Bioinformation. 2013;9(6):293-8. doi: 10.6026/97320630009293. Epub 2013 Mar 19.

PMID:
23559748
[PubMed]
Free PMC Article
2.

Modeling of human M1 aminopeptidases for in silico screening of potential Plasmodium falciparum alanine aminopeptidase (PfA-M1) specific inhibitors.

Sahi S, Rai S, Chaudhary M, Nain V.

Bioinformation. 2014 Aug 30;10(8):518-25. doi: 10.6026/97320630010518. eCollection 2014.

PMID:
25258488
[PubMed]
Free PMC Article
3.

Plasmodium chabaudi chabaudi and P. falciparum: inhibition of aminopeptidase and parasite growth by bestatin and nitrobestatin.

Nankya-Kitaka MF, Curley GP, Gavigan CS, Bell A, Dalton JP.

Parasitol Res. 1998 Jul;84(7):552-8.

PMID:
9694371
[PubMed - indexed for MEDLINE]
4.

Chemical target validation studies of aminopeptidase in malaria parasites using alpha-aminoalkylphosphonate and phosphonopeptide inhibitors.

Cunningham E, Drag M, Kafarski P, Bell A.

Antimicrob Agents Chemother. 2008 Sep;52(9):3221-8. doi: 10.1128/AAC.01327-07. Epub 2008 May 5.

PMID:
18458130
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase.

McGowan S, Porter CJ, Lowther J, Stack CM, Golding SJ, Skinner-Adams TS, Trenholme KR, Teuscher F, Donnelly SM, Grembecka J, Mucha A, Kafarski P, Degori R, Buckle AM, Gardiner DL, Whisstock JC, Dalton JP.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2537-42. doi: 10.1073/pnas.0807398106. Epub 2009 Feb 5.

PMID:
19196988
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development.

Stack CM, Lowther J, Cunningham E, Donnelly S, Gardiner DL, Trenholme KR, Skinner-Adams TS, Teuscher F, Grembecka J, Mucha A, Kafarski P, Lua L, Bell A, Dalton JP.

J Biol Chem. 2007 Jan 19;282(3):2069-80. Epub 2006 Nov 15.

PMID:
17107951
[PubMed - indexed for MEDLINE]
Free Article
7.

The Plasmodium falciparum malaria M1 alanyl aminopeptidase (PfA-M1): insights of catalytic mechanism and function from MD simulations.

Jones PM, Robinson MW, Dalton JP, George AM.

PLoS One. 2011;6(12):e28589. doi: 10.1371/journal.pone.0028589. Epub 2011 Dec 21.

PMID:
22205955
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Identification of Potent and Selective Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PfM18AAP) of Human Malaria via High-Throughput Screening.

Spicer T, Fernandez-Vega V, Chase P, Scampavia L, To J, Dalton JP, Da Silva FL, Skinner-Adams TS, Gardiner DL, Trenholme KR, Brown CL, Ghosh P, Porubsky P, Wang JL, Whipple DA, Schoenen FJ, Hodder P.

J Biomol Screen. 2014 Mar 11;19(7):1107-1115. [Epub ahead of print]

PMID:
24619116
[PubMed - as supplied by publisher]
9.

Comparison of proteases from chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum.

Vander Jagt DL, Hunsaker LA, Campos NM.

Biochem Pharmacol. 1987 Oct 1;36(19):3285-91.

PMID:
3311049
[PubMed - indexed for MEDLINE]
10.

Plasmodium falciparum PfA-M1 aminopeptidase is trafficked via the parasitophorous vacuole and marginally delivered to the food vacuole.

Azimzadeh O, Sow C, G├Ęze M, Nyalwidhe J, Florent I.

Malar J. 2010 Jun 30;9:189. doi: 10.1186/1475-2875-9-189.

PMID:
20591164
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malaria.

Skinner-Adams TS, Peatey CL, Anderson K, Trenholme KR, Krige D, Brown CL, Stack C, Nsangou DM, Mathews RT, Thivierge K, Dalton JP, Gardiner DL.

Antimicrob Agents Chemother. 2012 Jun;56(6):3244-9. doi: 10.1128/AAC.06245-11. Epub 2012 Mar 26.

PMID:
22450967
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

M17 leucine aminopeptidase of the human malaria parasite Plasmodium vivax.

Lee JY, Song SM, Seok JW, Jha BK, Han ET, Song HO, Yu HS, Hong Y, Kong HH, Chung DI.

Mol Biochem Parasitol. 2010 Mar;170(1):45-8. doi: 10.1016/j.molbiopara.2009.11.003. Epub 2009 Nov 18.

PMID:
19931315
[PubMed - indexed for MEDLINE]
13.

Properties, stage-dependent expression and localization of Plasmodium falciparum M1 family zinc-aminopeptidase.

Allary M, Schrevel J, Florent I.

Parasitology. 2002 Jul;125(Pt 1):1-10.

PMID:
12166515
[PubMed - indexed for MEDLINE]
14.

Purification and characterization of an aminopeptidase from Plasmodium falciparum.

Vander Jagt DL, Baack BR, Hunsaker LA.

Mol Biochem Parasitol. 1984 Jan;10(1):45-54.

PMID:
6363922
[PubMed - indexed for MEDLINE]
15.

Scanning alanine mutagenesis and de-peptidization of a Candida albicans myristoyl-CoA:protein N-myristoyltransferase octapeptide substrate reveals three elements critical for molecular recognition.

McWherter CA, Rocque WJ, Zupec ME, Freeman SK, Brown DL, Devadas B, Getman DP, Sikorski JA, Gordon JI.

J Biol Chem. 1997 May 2;272(18):11874-80.

PMID:
9115247
[PubMed - indexed for MEDLINE]
Free Article
16.

Overexpression of leucyl aminopeptidase in Plasmodium falciparum parasites. Target for the antimalarial activity of bestatin.

Gardiner DL, Trenholme KR, Skinner-Adams TS, Stack CM, Dalton JP.

J Biol Chem. 2006 Jan 20;281(3):1741-5. Epub 2005 Nov 14.

PMID:
16286469
[PubMed - indexed for MEDLINE]
Free Article
17.

The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum: importance of active site metal ions in the binding of substrates and inhibitors.

Maric S, Donnelly SM, Robinson MW, Skinner-Adams T, Trenholme KR, Gardiner DL, Dalton JP, Stack CM, Lowther J.

Biochemistry. 2009 Jun 16;48(23):5435-9. doi: 10.1021/bi9003638.

PMID:
19408962
[PubMed - indexed for MEDLINE]
18.

Roles for two aminopeptidases in vacuolar hemoglobin catabolism in Plasmodium falciparum.

Dalal S, Klemba M.

J Biol Chem. 2007 Dec 7;282(49):35978-87. Epub 2007 Sep 25.

PMID:
17895246
[PubMed - indexed for MEDLINE]
Free Article
20.

The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparum.

Teuscher F, Lowther J, Skinner-Adams TS, Spielmann T, Dixon MW, Stack CM, Donnelly S, Mucha A, Kafarski P, Vassiliou S, Gardiner DL, Dalton JP, Trenholme KR.

J Biol Chem. 2007 Oct 19;282(42):30817-26. Epub 2007 Aug 20.

PMID:
17720817
[PubMed - indexed for MEDLINE]
Free Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk