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Results: 1 to 20 of 99

1.

Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis.

Simonin Y, Vegna S, Akkari L, Grégoire D, Antoine E, Piette J, Floc'h N, Lassus P, Yu GY, Rosenberg AR, Karin M, Durantel D, Hibner U.

PLoS Pathog. 2013 Mar;9(3):e1003234. doi: 10.1371/journal.ppat.1003234. Epub 2013 Mar 21.

PMID:
23555249
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A lymphotoxin-driven pathway to hepatocellular carcinoma.

Haybaeck J, Zeller N, Wolf MJ, Weber A, Wagner U, Kurrer MO, Bremer J, Iezzi G, Graf R, Clavien PA, Thimme R, Blum H, Nedospasov SA, Zatloukal K, Ramzan M, Ciesek S, Pietschmann T, Marche PN, Karin M, Kopf M, Browning JL, Aguzzi A, Heikenwalder M.

Cancer Cell. 2009 Oct 6;16(4):295-308. doi: 10.1016/j.ccr.2009.08.021. Erratum in: Cancer Cell. 2009 Nov 6;16(5):447.

PMID:
19800575
[PubMed - indexed for MEDLINE]
Free Article
3.

Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on Toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates.

Li K, Li NL, Wei D, Pfeffer SR, Fan M, Pfeffer LM.

Hepatology. 2012 Mar;55(3):666-75. doi: 10.1002/hep.24763. Epub 2012 Jan 30.

PMID:
22030901
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Calpain activation by hepatitis C virus proteins inhibits the extrinsic apoptotic signaling pathway.

Simonin Y, Disson O, Lerat H, Antoine E, Binamé F, Rosenberg AR, Desagher S, Lassus P, Bioulac-Sage P, Hibner U.

Hepatology. 2009 Nov;50(5):1370-9. doi: 10.1002/hep.23169.

PMID:
19711428
[PubMed - indexed for MEDLINE]
5.

Hepatic expression of HCV RNA-dependent RNA polymerase triggers innate immune signaling and cytokine production.

Yu GY, He G, Li CY, Tang M, Grivennikov S, Tsai WT, Wu MS, Hsu CW, Tsai Y, Wang LH, Karin M.

Mol Cell. 2012 Oct 26;48(2):313-21. doi: 10.1016/j.molcel.2012.07.032. Epub 2012 Sep 6.

PMID:
22959272
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Inhibition of hepatitis C virus (HCV) replication by specific RNA aptamers against HCV NS5B RNA replicase.

Lee CH, Lee YJ, Kim JH, Lim JH, Kim JH, Han W, Lee SH, Noh GJ, Lee SW.

J Virol. 2013 Jun;87(12):7064-74. doi: 10.1128/JVI.00405-13. Epub 2013 Apr 17.

PMID:
23596299
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Induction of high-molecular-weight (HMW) tumor necrosis factor(TNF) alpha by hepatitis C virus (HCV) non-structural protein 3 (NS3) in liver cells is AP-1 and NF-kappaB-dependent activation.

Hassan M, Selimovic D, Ghozlan H, Abdel-Kader O.

Cell Signal. 2007 Feb;19(2):301-11. Epub 2006 Aug 17.

PMID:
16916598
[PubMed - indexed for MEDLINE]
8.

A cell-based assay for RNA synthesis by the HCV polymerase reveals new insights on mechanism of polymerase inhibitors and modulation by NS5A.

Ranjith-Kumar CT, Wen Y, Baxter N, Bhardwaj K, Cheng Kao C.

PLoS One. 2011;6(7):e22575. doi: 10.1371/journal.pone.0022575. Epub 2011 Jul 22.

PMID:
21799903
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity.

Ding Q, Cao X, Lu J, Huang B, Liu YJ, Kato N, Shu HB, Zhong J.

J Hepatol. 2013 Jul;59(1):52-8. doi: 10.1016/j.jhep.2013.03.019. Epub 2013 Mar 28.

PMID:
23542348
[PubMed - indexed for MEDLINE]
10.

Cleavage of the IPS-1/Cardif/MAVS/VISA does not inhibit T cell-mediated elimination of hepatitis C virus non-structural 3/4A-expressing hepatocytes.

Ahlén G, Derk E, Weiland M, Jiao J, Rahbin N, Aleman S, Peterson DL, Pokrovskaja K, Grandér D, Frelin L, Sällberg M.

Gut. 2009 Apr;58(4):560-9. doi: 10.1136/gut.2007.147264. Epub 2008 Aug 8.

PMID:
18689426
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Lymphotoxins: new targets for hepatocellular carcinoma.

Villanueva A, Savic R, Llovet JM.

Cancer Cell. 2009 Oct 6;16(4):272-3. doi: 10.1016/j.ccr.2009.09.012.

PMID:
19800570
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Hepatitis C virus triggers apoptosis of a newly developed hepatoma cell line through antiviral defense system.

Zhu H, Dong H, Eksioglu E, Hemming A, Cao M, Crawford JM, Nelson DR, Liu C.

Gastroenterology. 2007 Nov;133(5):1649-59. Epub 2007 Sep 16.

PMID:
17983809
[PubMed - indexed for MEDLINE]
14.

Hepatitis C virus-induced up-regulation of microRNA-155 promotes hepatocarcinogenesis by activating Wnt signaling.

Zhang Y, Wei W, Cheng N, Wang K, Li B, Jiang X, Sun S.

Hepatology. 2012 Nov;56(5):1631-40. doi: 10.1002/hep.25849. Epub 2012 Oct 9.

PMID:
22610915
[PubMed - indexed for MEDLINE]
15.

Hepatitis C virus-induced activation of β-catenin promotes c-Myc expression and a cascade of pro-carcinogenetic events.

Higgs MR, Lerat H, Pawlotsky JM.

Oncogene. 2013 Sep 26;32(39):4683-93. doi: 10.1038/onc.2012.484. Epub 2012 Oct 29.

PMID:
23108410
[PubMed - indexed for MEDLINE]
16.

HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons.

Thomas E, Gonzalez VD, Li Q, Modi AA, Chen W, Noureddin M, Rotman Y, Liang TJ.

Gastroenterology. 2012 Apr;142(4):978-88. doi: 10.1053/j.gastro.2011.12.055. Epub 2012 Jan 13.

PMID:
22248663
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma.

Pereira Tde A, Witek RP, Syn WK, Choi SS, Bradrick S, Karaca GF, Agboola KM, Jung Y, Omenetti A, Moylan CA, Yang L, Fernandez-Zapico ME, Jhaveri R, Shah VH, Pereira FE, Diehl AM.

Lab Invest. 2010 Dec;90(12):1690-703. doi: 10.1038/labinvest.2010.147. Epub 2010 Aug 9.

PMID:
20697376
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Hepatitis C virus-induced cancer stem cell-like signatures in cell culture and murine tumor xenografts.

Ali N, Allam H, May R, Sureban SM, Bronze MS, Bader T, Umar S, Anant S, Houchen CW.

J Virol. 2011 Dec;85(23):12292-303. doi: 10.1128/JVI.05920-11. Epub 2011 Sep 21.

PMID:
21937640
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Liver stem cells: implications for hepatocarcinogenesis.

Alison MR.

Stem Cell Rev. 2005;1(3):253-60. Review.

PMID:
17142862
[PubMed - indexed for MEDLINE]
20.

Nonstructural 5A protein activates beta-catenin signaling cascades: implication of hepatitis C virus-induced liver pathogenesis.

Park CY, Choi SH, Kang SM, Kang JI, Ahn BY, Kim H, Jung G, Choi KY, Hwang SB.

J Hepatol. 2009 Nov;51(5):853-64. doi: 10.1016/j.jhep.2009.06.026. Epub 2009 Aug 12.

PMID:
19726098
[PubMed - indexed for MEDLINE]

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