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Results: 1 to 20 of 113

1.

Repression of Zeb1 and hypoxia cause sequential mesenchymal-to-epithelial transition and induction of aid, Oct4, and Dnmt1, leading to immortalization and multipotential reprogramming of fibroblasts in spheres.

Liu Y, Mukhopadhyay P, Pisano MM, Lu X, Huang L, Lu Q, Dean DC.

Stem Cells. 2013 Jul;31(7):1350-62. doi: 10.1002/stem.1382.

PMID:
23554223
[PubMed - indexed for MEDLINE]
2.

Reprogramming towards pluripotency requires AID-dependent DNA demethylation.

Bhutani N, Brady JJ, Damian M, Sacco A, Corbel SY, Blau HM.

Nature. 2010 Feb 25;463(7284):1042-7. doi: 10.1038/nature08752.

PMID:
20027182
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Zeb1 links epithelial-mesenchymal transition and cellular senescence.

Liu Y, El-Naggar S, Darling DS, Higashi Y, Dean DC.

Development. 2008 Feb;135(3):579-88. doi: 10.1242/dev.007047.

PMID:
18192284
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation.

Wang G, Guo X, Hong W, Liu Q, Wei T, Lu C, Gao L, Ye D, Zhou Y, Chen J, Wang J, Wu M, Liu H, Kang J.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2858-63. doi: 10.1073/pnas.1212769110. Epub 2013 Feb 5.

PMID:
23386720
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone.

Chen J, Liu J, Yang J, Chen Y, Chen J, Ni S, Song H, Zeng L, Ding K, Pei D.

Cell Res. 2011 Jan;21(1):205-12. doi: 10.1038/cr.2010.172. Epub 2010 Dec 7.

PMID:
21135873
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds.

Shi Y, Desponts C, Do JT, Hahm HS, Schöler HR, Ding S.

Cell Stem Cell. 2008 Nov 6;3(5):568-74. doi: 10.1016/j.stem.2008.10.004.

PMID:
18983970
[PubMed - indexed for MEDLINE]
Free Article
7.

Reprogramming of human somatic cells to pluripotency with defined factors.

Park IH, Zhao R, West JA, Yabuuchi A, Huo H, Ince TA, Lerou PH, Lensch MW, Daley GQ.

Nature. 2008 Jan 10;451(7175):141-6. Epub 2007 Dec 23.

PMID:
18157115
[PubMed - indexed for MEDLINE]
8.

C/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells.

Di Stefano B, Sardina JL, van Oevelen C, Collombet S, Kallin EM, Vicent GP, Lu J, Thieffry D, Beato M, Graf T.

Nature. 2014 Feb 13;506(7487):235-9. doi: 10.1038/nature12885. Epub 2013 Dec 15.

PMID:
24336202
[PubMed - indexed for MEDLINE]
9.

Chromatin states of core pluripotency-associated genes in pluripotent, multipotent and differentiated cells.

Barrand S, Collas P.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):762-7. doi: 10.1016/j.bbrc.2009.11.134. Epub 2009 Nov 26.

PMID:
19944068
[PubMed - indexed for MEDLINE]
10.

Gata4 blocks somatic cell reprogramming by directly repressing Nanog.

Serrano F, Calatayud CF, Blazquez M, Torres J, Castell JV, Bort R.

Stem Cells. 2013 Jan;31(1):71-82. doi: 10.1002/stem.1272.

PMID:
23132827
[PubMed - indexed for MEDLINE]
11.

Molecular insights into reprogramming-initiation events mediated by the OSKM gene regulatory network.

Mah N, Wang Y, Liao MC, Prigione A, Jozefczuk J, Lichtner B, Wolfrum K, Haltmeier M, Flöttmann M, Schaefer M, Hahn A, Mrowka R, Klipp E, Andrade-Navarro MA, Adjaye J.

PLoS One. 2011;6(8):e24351. doi: 10.1371/journal.pone.0024351. Epub 2011 Aug 31.

PMID:
21909390
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Reprogramming of mouse fibroblasts into induced pluripotent stem cells with Nanog.

Moon JH, Yun W, Kim J, Hyeon S, Kang PJ, Park G, Kim A, Oh S, Whang KY, Kim DW, Yoon BS, You S.

Biochem Biophys Res Commun. 2013 Feb 15;431(3):444-9. doi: 10.1016/j.bbrc.2012.12.149. Epub 2013 Jan 16.

PMID:
23333380
[PubMed - indexed for MEDLINE]
13.

Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation.

Kumar SM, Liu S, Lu H, Zhang H, Zhang PJ, Gimotty PA, Guerra M, Guo W, Xu X.

Oncogene. 2012 Nov 22;31(47):4898-911. doi: 10.1038/onc.2011.656. Epub 2012 Jan 30.

PMID:
22286766
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Differential recruitment of methyl CpG-binding domain factors and DNA methyltransferases by the orphan receptor germ cell nuclear factor initiates the repression and silencing of Oct4.

Gu P, Xu X, Le Menuet D, Chung AC, Cooney AJ.

Stem Cells. 2011 Jul;29(7):1041-51. doi: 10.1002/stem.652.

PMID:
21608077
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules.

Li Y, Zhang Q, Yin X, Yang W, Du Y, Hou P, Ge J, Liu C, Zhang W, Zhang X, Wu Y, Li H, Liu K, Wu C, Song Z, Zhao Y, Shi Y, Deng H.

Cell Res. 2011 Jan;21(1):196-204. doi: 10.1038/cr.2010.142. Epub 2010 Oct 19.

PMID:
20956998
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Derivation, characterization and retinal differentiation of induced pluripotent stem cells.

Mekala SR, Vauhini V, Nagarajan U, Maddileti S, Gaddipati S, Mariappan I.

J Biosci. 2013 Mar;38(1):123-34.

PMID:
23385820
[PubMed - indexed for MEDLINE]
Free Article
17.

Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.

Chiou SH, Wang ML, Chou YT, Chen CJ, Hong CF, Hsieh WJ, Chang HT, Chen YS, Lin TW, Hsu HS, Wu CW.

Cancer Res. 2010 Dec 15;70(24):10433-44. doi: 10.1158/0008-5472.CAN-10-2638.

PMID:
21159654
[PubMed - indexed for MEDLINE]
Free Article
18.

Sequential inductions of the ZEB1 transcription factor caused by mutation of Rb and then Ras proteins are required for tumor initiation and progression.

Liu Y, Sánchez-Tilló E, Lu X, Huang L, Clem B, Telang S, Jenson AB, Cuatrecasas M, Chesney J, Postigo A, Dean DC.

J Biol Chem. 2013 Apr 19;288(16):11572-80. doi: 10.1074/jbc.M112.434951. Epub 2013 Feb 26.

PMID:
23443660
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT-MET mechanism for optimal reprogramming.

Liu X, Sun H, Qi J, Wang L, He S, Liu J, Feng C, Chen C, Li W, Guo Y, Qin D, Pan G, Chen J, Pei D, Zheng H.

Nat Cell Biol. 2013 Jul;15(7):829-38. doi: 10.1038/ncb2765. Epub 2013 May 26.

PMID:
23708003
[PubMed - indexed for MEDLINE]
20.

Activation-induced deaminase-coupled DNA demethylation is not crucial for the generation of induced pluripotent stem cells.

Habib O, Habib G, Do JT, Moon SH, Chung HM.

Stem Cells Dev. 2014 Feb 1;23(3):209-18. doi: 10.1089/scd.2013.0337. Epub 2013 Nov 12.

PMID:
24083501
[PubMed - indexed for MEDLINE]

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