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Items: 1 to 20 of 456

1.

Stem cell marker nestin is critical for TGF-β1-mediated tumor progression in pancreatic cancer.

Su HT, Weng CC, Hsiao PJ, Chen LH, Kuo TL, Chen YW, Kuo KK, Cheng KH.

Mol Cancer Res. 2013 Jul;11(7):768-79. doi: 10.1158/1541-7786.MCR-12-0511. Epub 2013 Apr 3.

2.

SMAD4 loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells.

Chen YW, Hsiao PJ, Weng CC, Kuo KK, Kuo TL, Wu DC, Hung WC, Cheng KH.

BMC Cancer. 2014 Mar 14;14:181. doi: 10.1186/1471-2407-14-181.

3.

Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling.

Ungefroren H, Sebens S, Giehl K, Helm O, Groth S, Fändrich F, Röcken C, Sipos B, Lehnert H, Gieseler F.

Oncotarget. 2014 Jan 15;5(1):277-90.

4.

Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.

Bardeesy N, Cheng KH, Berger JH, Chu GC, Pahler J, Olson P, Hezel AF, Horner J, Lauwers GY, Hanahan D, DePinho RA.

Genes Dev. 2006 Nov 15;20(22):3130-46.

5.

Biomarkers of TGF-β signaling pathway and prognosis of pancreatic cancer.

Javle M, Li Y, Tan D, Dong X, Chang P, Kar S, Li D.

PLoS One. 2014 Jan 20;9(1):e85942. doi: 10.1371/journal.pone.0085942. eCollection 2014.

6.

Upregulated SMAD3 promotes epithelial-mesenchymal transition and predicts poor prognosis in pancreatic ductal adenocarcinoma.

Yamazaki K, Masugi Y, Effendi K, Tsujikawa H, Hiraoka N, Kitago M, Shinoda M, Itano O, Tanabe M, Kitagawa Y, Sakamoto M.

Lab Invest. 2014 Jun;94(6):683-91. doi: 10.1038/labinvest.2014.53. Epub 2014 Apr 7.

7.

Yes-associated protein (YAP65) in relation to Smad7 expression in human pancreatic ductal adenocarcinoma.

Guo J, Kleeff J, Zhao Y, Li J, Giese T, Esposito I, Büchler MW, Korc M, Friess H.

Int J Mol Med. 2006 May;17(5):761-7.

PMID:
16596258
8.

Kindlin-2 induced by TGF-β signaling promotes pancreatic ductal adenocarcinoma progression through downregulation of transcriptional factor HOXB9.

Zhan J, Song J, Wang P, Chi X, Wang Y, Guo Y, Fang W, Zhang H.

Cancer Lett. 2015 May 28;361(1):75-85. doi: 10.1016/j.canlet.2015.02.039. Epub 2015 Feb 24.

PMID:
25724625
9.

Differential roles of Smad2 and Smad3 in the regulation of TGF-β1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1.

Ungefroren H, Groth S, Sebens S, Lehnert H, Gieseler F, Fändrich F.

Mol Cancer. 2011 May 30;10:67. doi: 10.1186/1476-4598-10-67.

10.

Down-regulation of microRNA-494 via loss of SMAD4 increases FOXM1 and β-catenin signaling in pancreatic ductal adenocarcinoma cells.

Li L, Li Z, Kong X, Xie D, Jia Z, Jiang W, Cui J, Du Y, Wei D, Huang S, Xie K.

Gastroenterology. 2014 Aug;147(2):485-97.e18. doi: 10.1053/j.gastro.2014.04.048. Epub 2014 May 20.

PMID:
24859161
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12.

Differential roles of Src in transforming growth factor-ß regulation of growth arrest, epithelial-to-mesenchymal transition and cell migration in pancreatic ductal adenocarcinoma cells.

Ungefroren H, Sebens S, Groth S, Gieseler F, Fändrich F.

Int J Oncol. 2011 Mar;38(3):797-805. doi: 10.3892/ijo.2011.897. Epub 2011 Jan 11.

PMID:
21225226
13.

Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model.

Boreddy SR, Srivastava SK.

Oncogene. 2013 Aug 22;32(34):3980-91. doi: 10.1038/onc.2012.413. Epub 2012 Sep 17.

14.

Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: role in malignant transformation of pancreatic cancer.

Geismann C, Morscheck M, Koch D, Bergmann F, Ungefroren H, Arlt A, Tsao MS, Bachem MG, Altevogt P, Sipos B, Fölsch UR, Schäfer H, Müerköster SS.

Cancer Res. 2009 May 15;69(10):4517-26. doi: 10.1158/0008-5472.CAN-08-3493. Epub 2009 May 12.

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Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition.

Mizuuchi Y, Aishima S, Ohuchida K, Shindo K, Fujino M, Hattori M, Miyazaki T, Mizumoto K, Tanaka M, Oda Y.

Lab Invest. 2015 Feb;95(2):193-206. doi: 10.1038/labinvest.2014.138. Epub 2014 Nov 24.

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Loss of canonical Smad4 signaling promotes KRAS driven malignant transformation of human pancreatic duct epithelial cells and metastasis.

Leung L, Radulovich N, Zhu CQ, Wang D, To C, Ibrahimov E, Tsao MS.

PLoS One. 2013 Dec 27;8(12):e84366. doi: 10.1371/journal.pone.0084366. eCollection 2013.

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