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Results: 1 to 20 of 84

1.

Myeloid cell-specific serine palmitoyltransferase subunit 2 haploinsufficiency reduces murine atherosclerosis.

Chakraborty M, Lou C, Huan C, Kuo MS, Park TS, Cao G, Jiang XC.

J Clin Invest. 2013 Apr 1;123(4):1784-97. doi: 10.1172/JCI60415. Epub 2013 Mar 15. Erratum in: J Clin Invest. 2013 May;123(5):2332.

PMID:
23549085
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Liver-specific deficiency of serine palmitoyltransferase subunit 2 decreases plasma sphingomyelin and increases apolipoprotein E levels.

Li Z, Li Y, Chakraborty M, Fan Y, Bui HH, Peake DA, Kuo MS, Xiao X, Cao G, Jiang XC.

J Biol Chem. 2009 Sep 25;284(39):27010-9. doi: 10.1074/jbc.M109.042028. Epub 2009 Aug 1.

PMID:
19648608
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Endotoxin activates de novo sphingolipid biosynthesis via nuclear factor kappa B-mediated upregulation of Sptlc2.

Chang ZQ, Lee SY, Kim HJ, Kim JR, Kim SJ, Hong IK, Oh BC, Choi CS, Goldberg IJ, Park TS.

Prostaglandins Other Lipid Mediat. 2011 Feb;94(1-2):44-52. doi: 10.1016/j.prostaglandins.2010.12.003. Epub 2010 Dec 15.

PMID:
21167294
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Reducing plasma membrane sphingomyelin increases insulin sensitivity.

Li Z, Zhang H, Liu J, Liang CP, Li Y, Li Y, Teitelman G, Beyer T, Bui HH, Peake DA, Zhang Y, Sanders PE, Kuo MS, Park TS, Cao G, Jiang XC.

Mol Cell Biol. 2011 Oct;31(20):4205-18. doi: 10.1128/MCB.05893-11. Epub 2011 Aug 15.

PMID:
21844222
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice.

Lammers B, Chandak PG, Aflaki E, Van Puijvelde GH, Radovic B, Hildebrand RB, Meurs I, Out R, Kuiper J, Van Berkel TJ, Kolb D, Haemmerle G, Zechner R, Levak-Frank S, Van Eck M, Kratky D.

Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):67-73. doi: 10.1161/ATVBAHA.110.215814. Epub 2010 Oct 28.

PMID:
21030715
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Impact of sphingomyelin synthase 1 deficiency on sphingolipid metabolism and atherosclerosis in mice.

Li Z, Fan Y, Liu J, Li Y, Huan C, Bui HH, Kuo MS, Park TS, Cao G, Jiang XC.

Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1577-84. doi: 10.1161/ATVBAHA.112.251538. Epub 2012 May 10.

PMID:
22580896
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice.

Wang F, Okamoto Y, Inoki I, Yoshioka K, Du W, Qi X, Takuwa N, Gonda K, Yamamoto Y, Ohkawa R, Nishiuchi T, Sugimoto N, Yatomi Y, Mitsumori K, Asano M, Kinoshita M, Takuwa Y.

J Clin Invest. 2010 Nov;120(11):3979-95. doi: 10.1172/JCI42315. Epub 2010 Oct 18. Erratum in: J Clin Invest. 2012 Jan;122(1):419. Retraction in: J Clin Invest. 2012 Mar 1;122(3):1131.

PMID:
20978351
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice.

Hojjati MR, Li Z, Jiang XC.

Biochim Biophys Acta. 2005 Oct 15;1737(1):44-51. Epub 2005 Aug 24.

PMID:
16216550
[PubMed - indexed for MEDLINE]
Free Article
9.

Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol.

Li Z, Park TS, Li Y, Pan X, Iqbal J, Lu D, Tang W, Yu L, Goldberg IJ, Hussain MM, Jiang XC.

Biochim Biophys Acta. 2009 Apr;1791(4):297-306. doi: 10.1016/j.bbalip.2009.01.010. Epub 2009 Jan 29.

PMID:
19416652
[PubMed - indexed for MEDLINE]
Free Article
10.

The role of MyD88 and TLR4 in the LPS-mimetic activity of Taxol.

Byrd-Leifer CA, Block EF, Takeda K, Akira S, Ding A.

Eur J Immunol. 2001 Aug;31(8):2448-57.

PMID:
11500829
[PubMed - indexed for MEDLINE]
11.

Rip2 deficiency leads to increased atherosclerosis despite decreased inflammation.

Levin MC, Jirholt P, Wramstedt A, Johansson ME, Lundberg AM, Trajkovska MG, Ståhlman M, Fogelstrand P, Brisslert M, Fogelstrand L, Yan ZQ, Hansson GK, Björkbacka H, Olofsson SO, Borén J.

Circ Res. 2011 Nov 11;109(11):1210-8. doi: 10.1161/CIRCRESAHA.111.246702. Epub 2011 Sep 29.

PMID:
21959219
[PubMed - indexed for MEDLINE]
Free Article
12.

Adipocyte enhancer-binding protein 1 (AEBP1) (a novel macrophage proinflammatory mediator) overexpression promotes and ablation attenuates atherosclerosis in ApoE (-/-) and LDLR (-/-) mice.

Bogachev O, Majdalawieh A, Pan X, Zhang L, Ro HS.

Mol Med. 2011 Sep-Oct;17(9-10):1056-64. doi: 10.2119/molmed.2011.00141. Epub 2011 Jun 14.

PMID:
21687917
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Macrophage expression of peroxisome proliferator-activated receptor-alpha reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.

Babaev VR, Ishiguro H, Ding L, Yancey PG, Dove DE, Kovacs WJ, Semenkovich CF, Fazio S, Linton MF.

Circulation. 2007 Sep 18;116(12):1404-12. Epub 2007 Aug 27.

PMID:
17724261
[PubMed - indexed for MEDLINE]
Free Article
14.

The absence of macrophage Nrf2 promotes early atherogenesis.

Ruotsalainen AK, Inkala M, Partanen ME, Lappalainen JP, Kansanen E, Mäkinen PI, Heinonen SE, Laitinen HM, Heikkilä J, Vatanen T, Hörkkö S, Yamamoto M, Ylä-Herttuala S, Jauhiainen M, Levonen AL.

Cardiovasc Res. 2013 Apr 1;98(1):107-15. doi: 10.1093/cvr/cvt008. Epub 2013 Jan 22.

PMID:
23341579
[PubMed - indexed for MEDLINE]
Free Article
15.

Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components.

Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, Ren T, Cody MJ, Michalek SM, Rice NR, Vogel SN.

J Immunol. 2003 Jan 1;170(1):508-19.

PMID:
12496438
[PubMed - indexed for MEDLINE]
Free Article
16.

[Sphingomyelin synthase 2 deficiency decreases atherosclerosis and inhibits inflammation in mice].

Qin R, Chen ML, Zhu K, Deng JB, Shi YY.

Sheng Li Xue Bao. 2010 Aug 25;62(4):333-8. Chinese.

PMID:
20717634
[PubMed - indexed for MEDLINE]
Free Article
17.

Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?

Hornemann T, Wei Y, von Eckardstein A.

Biochem J. 2007 Jul 1;405(1):157-64.

PMID:
17331073
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Systemic deficiency of the MAP kinase-activated protein kinase 2 reduces atherosclerosis in hypercholesterolemic mice.

Jagavelu K, Tietge UJ, Gaestel M, Drexler H, Schieffer B, Bavendiek U.

Circ Res. 2007 Nov 26;101(11):1104-12. Epub 2007 Sep 20.

PMID:
17885219
[PubMed - indexed for MEDLINE]
Free Article
19.

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

Kanters E, Pasparakis M, Gijbels MJ, Vergouwe MN, Partouns-Hendriks I, Fijneman RJ, Clausen BE, Förster I, Kockx MM, Rajewsky K, Kraal G, Hofker MH, de Winther MP.

J Clin Invest. 2003 Oct;112(8):1176-85.

PMID:
14561702
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice.

Out R, Hoekstra M, Hildebrand RB, Kruit JK, Meurs I, Li Z, Kuipers F, Van Berkel TJ, Van Eck M.

Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2295-300. Epub 2006 Jul 20.

PMID:
16857950
[PubMed - indexed for MEDLINE]
Free Article

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