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Items: 1 to 20 of 195

1.

Estrogen receptor-α variant, ER-α36, is involved in tamoxifen resistance and estrogen hypersensitivity.

Zhang X, Wang ZY.

Endocrinology. 2013 Jun;154(6):1990-8. doi: 10.1210/en.2013-1116. Epub 2013 Apr 1.

PMID:
23546601
2.

ER-alpha36, a variant of ER-alpha, promotes tamoxifen agonist action in endometrial cancer cells via the MAPK/ERK and PI3K/Akt pathways.

Lin SL, Yan LY, Zhang XT, Yuan J, Li M, Qiao J, Wang ZY, Sun QY.

PLoS One. 2010 Feb 2;5(2):e9013. doi: 10.1371/journal.pone.0009013.

3.

Estrogen receptor-α36 is involved in development of acquired tamoxifen resistance via regulating the growth status switch in breast cancer cells.

Li G, Zhang J, Jin K, He K, Zheng Y, Xu X, Wang H, Wang H, Li Z, Yu X, Teng X, Cao J, Teng L.

Mol Oncol. 2013 Jun;7(3):611-24. doi: 10.1016/j.molonc.2013.02.001. Epub 2013 Feb 26.

4.

Disruption of the ER-α36-EGFR/HER2 positive regulatory loops restores tamoxifen sensitivity in tamoxifen resistance breast cancer cells.

Yin L, Zhang XT, Bian XW, Guo YM, Wang ZY.

PLoS One. 2014 Sep 9;9(9):e107369. doi: 10.1371/journal.pone.0107369. eCollection 2014.

5.

ER-α36, a novel variant of ER-α, mediates estrogen-stimulated proliferation of endometrial carcinoma cells via the PKCδ/ERK pathway.

Tong JS, Zhang QH, Wang ZB, Li S, Yang CR, Fu XQ, Hou Y, Wang ZY, Sheng J, Sun QY.

PLoS One. 2010 Nov 4;5(11):e15408. doi: 10.1371/journal.pone.0015408.

6.

Keratinocyte growth factor (KGF) induces tamoxifen (Tam) resistance in human breast cancer MCF-7 cells.

Chang HL, Sugimoto Y, Liu S, Ye W, Wang LS, Huang YW, Lin YC.

Anticancer Res. 2006 May-Jun;26(3A):1773-84.

7.

Estrogen activation of the mitogen-activated protein kinase is mediated by ER-α36 in ER-positive breast cancer cells.

Zhang X, Deng H, Wang ZY.

J Steroid Biochem Mol Biol. 2014 Sep;143:434-43. doi: 10.1016/j.jsbmb.2014.06.009. Epub 2014 Jun 25.

PMID:
24973581
8.

Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells.

Li Z, Wang N, Fang J, Huang J, Tian F, Li C, Xie F.

Oncol Rep. 2012 Jun;27(6):1879-86. doi: 10.3892/or.2012.1728. Epub 2012 Mar 15.

PMID:
22427054
9.

let-7 microRNAs induce tamoxifen sensitivity by downregulation of estrogen receptor α signaling in breast cancer.

Zhao Y, Deng C, Lu W, Xiao J, Ma D, Guo M, Recker RR, Gatalica Z, Wang Z, Xiao GG.

Mol Med. 2011;17(11-12):1233-41. doi: 10.2119/molmed.2010.00225. Epub 2011 Jul 27.

10.

Synuclein gamma stimulates membrane-initiated estrogen signaling by chaperoning estrogen receptor (ER)-alpha36, a variant of ER-alpha.

Shi YE, Chen Y, Dackour R, Potters L, Wang S, Ding Q, Wang Z, Liu YE.

Am J Pathol. 2010 Aug;177(2):964-73. doi: 10.2353/ajpath.2010.100061. Epub 2010 Jul 1.

11.

ER-α variant ER-α36 mediates antiestrogen resistance in ER-positive breast cancer stem/progenitor cells.

Deng H, Yin L, Zhang XT, Liu LJ, Wang ML, Wang ZY.

J Steroid Biochem Mol Biol. 2014 Oct;144 Pt B:417-26. doi: 10.1016/j.jsbmb.2014.08.017. Epub 2014 Aug 23.

PMID:
25158023
12.

Estrogen receptor-α36 is involved in pterostilbene-induced apoptosis and anti-proliferation in in vitro and in vivo breast cancer.

Pan C, Hu Y, Li J, Wang Z, Huang J, Zhang S, Ding L.

PLoS One. 2014 Aug 15;9(8):e104459. doi: 10.1371/journal.pone.0104459. eCollection 2014.

13.

Downregulation of ER-α36 expression sensitizes HER2 overexpressing breast cancer cells to tamoxifen.

Yin L, Pan X, Zhang XT, Guo YM, Wang ZY, Gong Y, Wang M.

Am J Cancer Res. 2015 Jan 15;5(2):530-44. eCollection 2015.

14.

HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression.

Shah N, Jin K, Cruz LA, Park S, Sadik H, Cho S, Goswami CP, Nakshatri H, Gupta R, Chang HY, Zhang Z, Cimino-Mathews A, Cope L, Umbricht C, Sukumar S.

Cancer Res. 2013 Sep 1;73(17):5449-58. doi: 10.1158/0008-5472.CAN-13-1178. Epub 2013 Jul 5.

15.

ERBB2 influences the subcellular localization of the estrogen receptor in tamoxifen-resistant MCF-7 cells leading to the activation of AKT and RPS6KA2.

Pancholi S, Lykkesfeldt AE, Hilmi C, Banerjee S, Leary A, Drury S, Johnston S, Dowsett M, Martin LA.

Endocr Relat Cancer. 2008 Dec;15(4):985-1002. doi: 10.1677/ERC-07-0240. Epub 2008 Sep 29.

16.

Investigation of elemene-induced reversal of tamoxifen resistance in MCF-7 cells through oestrogen receptor α (ERα) re-expression.

Zhang B, Zhang X, Tang B, Zheng P, Zhang Y.

Breast Cancer Res Treat. 2012 Nov;136(2):399-406. doi: 10.1007/s10549-012-2263-6. Epub 2012 Sep 30.

PMID:
23053650
17.
19.

Ubiquitin ligase c-Cbl is involved in tamoxifen-induced apoptosis of MCF-7 cells by downregulating the survival signals.

Yan SC, Liu YP, Zhang LY, Qu JL, Xu L, Liu J, Zhang Y, Hou KZ, Teng YE, Qu XJ.

Acta Oncol. 2011 Jun;50(5):693-9. doi: 10.3109/0284186X.2010.543144. Epub 2010 Dec 22.

PMID:
21175263
20.

A positive feedback loop of ER-α36/EGFR promotes malignant growth of ER-negative breast cancer cells.

Zhang XT, Kang LG, Ding L, Vranic S, Gatalica Z, Wang ZY.

Oncogene. 2011 Feb 17;30(7):770-80. doi: 10.1038/onc.2010.458. Epub 2010 Oct 11.

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