Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 104

1.

Synthesis and anti-H5N1 activity of chiral gossypol derivatives and its analogs implicated by a viral entry blocking mechanism.

Yang J, Chen G, Li LL, Pan W, Zhang F, Yang J, Wu S, Tien P.

Bioorg Med Chem Lett. 2013 May 1;23(9):2619-23. doi: 10.1016/j.bmcl.2013.02.101. Epub 2013 Mar 7.

PMID:
23538114
[PubMed - indexed for MEDLINE]
2.

Synthesis and antiviral activities of novel gossypol derivatives.

Yang J, Zhang F, Li J, Chen G, Wu S, Ouyang W, Pan W, Yu R, Yang J, Tien P.

Bioorg Med Chem Lett. 2012 Feb 1;22(3):1415-20. doi: 10.1016/j.bmcl.2011.12.076. Epub 2011 Dec 21.

PMID:
22226654
[PubMed - indexed for MEDLINE]
3.

Chiral gossypol derivatives: evaluation of their anticancer activity and molecular modeling.

Zhang L, Jiang H, Cao X, Zhao H, Wang F, Cui Y, Jiang B.

Eur J Med Chem. 2009 Oct;44(10):3961-72. doi: 10.1016/j.ejmech.2009.04.025. Epub 2009 Apr 22.

PMID:
19447525
[PubMed - indexed for MEDLINE]
4.

Structure-activity relationships of saponin derivatives: a series of entry inhibitors for highly pathogenic H5N1 influenza virus.

Ding N, Chen Q, Zhang W, Ren S, Guo Y, Li Y.

Eur J Med Chem. 2012 Jul;53:316-26. doi: 10.1016/j.ejmech.2012.04.022. Epub 2012 Apr 21.

PMID:
22575533
[PubMed - indexed for MEDLINE]
5.

Discovery of the first series of small molecule H5N1 entry inhibitors.

Song G, Yang S, Zhang W, Cao Y, Wang P, Ding N, Zhang Z, Guo Y, Li Y.

J Med Chem. 2009 Dec 10;52(23):7368-71. doi: 10.1021/jm900275m.

PMID:
19537689
[PubMed - indexed for MEDLINE]
6.

Amino acid derivatives of the (-) enantiomer of gossypol are effective fusion inhibitors of human immunodeficiency virus type 1.

An T, Ouyang W, Pan W, Guo D, Li J, Li L, Chen G, Yang J, Wu S, Tien P.

Antiviral Res. 2012 Jun;94(3):276-87. doi: 10.1016/j.antiviral.2012.02.014. Epub 2012 Mar 8.

PMID:
22426469
[PubMed - indexed for MEDLINE]
7.

Design, synthesis and structure-activity relationship of novel inhibitors against H5N1 hemagglutinin-mediated membrane fusion.

Zhu Z, Li R, Xiao G, Chen Z, Yang J, Zhu Q, Liu S.

Eur J Med Chem. 2012 Nov;57:211-6. doi: 10.1016/j.ejmech.2012.08.041. Epub 2012 Sep 7.

PMID:
23059548
[PubMed - indexed for MEDLINE]
8.

CL-385319 inhibits H5N1 avian influenza A virus infection by blocking viral entry.

Liu S, Li R, Zhang R, Chan CC, Xi B, Zhu Z, Yang J, Poon VK, Zhou J, Chen M, M√ľnch J, Kirchhoff F, Pleschka S, Haarmann T, Dietrich U, Pan C, Du L, Jiang S, Zheng B.

Eur J Pharmacol. 2011 Jun 25;660(2-3):460-7. doi: 10.1016/j.ejphar.2011.04.013. Epub 2011 Apr 22.

PMID:
21536025
[PubMed - indexed for MEDLINE]
9.

Synthesis and screening of some novel fused thiophene and thienopyrimidine derivatives for anti-avian influenza virus (H5N1) activity.

Rashad AE, Shamroukh AH, Abdel-Megeid RE, Mostafa A, el-Shesheny R, Kandeil A, Ali MA, Banert K.

Eur J Med Chem. 2010 Nov;45(11):5251-7. doi: 10.1016/j.ejmech.2010.08.044. Epub 2010 Aug 24.

PMID:
20828882
[PubMed - indexed for MEDLINE]
10.

(-)-Carbodine: enantiomeric synthesis and in vitro antiviral activity against various strains of influenza virus including H5N1 (avian influenza) and novel 2009 H1N1 (swine flu).

Rao JR, Jha AK, Rawal RK, Sharon A, Day CW, Barnard DL, Smee DF, Chu CK.

Bioorg Med Chem Lett. 2010 Apr 15;20(8):2601-4. doi: 10.1016/j.bmcl.2010.02.074. Epub 2010 Feb 21.

PMID:
20231094
[PubMed - indexed for MEDLINE]
11.

A facile synthesis and anti-avian influenza virus (H5N1) screening of some novel pyrazolopyrimidine nucleoside derivatives.

Rashad AE, Shamroukh AH, Abdel-Megeid RE, Mostafa A, Ali MA, Banert K.

Nucleosides Nucleotides Nucleic Acids. 2010 Nov;29(11):809-20. doi: 10.1080/15257770.2010.529480.

PMID:
21128168
[PubMed - indexed for MEDLINE]
12.

Synthesis of gossypol atropisomers and derivatives and evaluation of their anti-proliferative and anti-oxidant activity.

Dodou K, Anderson RJ, Lough WJ, Small DA, Shelley MD, Groundwater PW.

Bioorg Med Chem. 2005 Jul 1;13(13):4228-37.

PMID:
15878283
[PubMed - indexed for MEDLINE]
13.

Design, synthesis, and in vitro biological evaluation of 1H-1,2,3-triazole-4-carboxamide derivatives as new anti-influenza A agents targeting virus nucleoprotein.

Cheng H, Wan J, Lin MI, Liu Y, Lu X, Liu J, Xu Y, Chen J, Tu Z, Cheng YS, Ding K.

J Med Chem. 2012 Mar 8;55(5):2144-53. doi: 10.1021/jm2013503. Epub 2012 Feb 27.

PMID:
22332894
[PubMed - indexed for MEDLINE]
14.

Selection of an antiviral RNA aptamer against hemagglutinin of the subtype H5 avian influenza virus.

Park SY, Kim S, Yoon H, Kim KB, Kalme SS, Oh S, Song CS, Kim DE.

Nucleic Acid Ther. 2011 Dec;21(6):395-402. doi: 10.1089/nat.2011.0321. Epub 2011 Oct 21.

PMID:
22017542
[PubMed - indexed for MEDLINE]
15.

Synthesis and anti-HIV activity of 1,1'-dideoxygossypol and related compounds.

Royer RE, Deck LM, Vander Jagt TJ, Martinez FJ, Mills RG, Young SA, Vander Jagt DL.

J Med Chem. 1995 Jun 23;38(13):2427-32.

PMID:
7608907
[PubMed - indexed for MEDLINE]
16.

Antiviral activities of gossypol and its derivatives against herpes simplex virus type II.

Radloff RJ, Deck LM, Royer RE, Vander Jagt DL.

Pharmacol Res Commun. 1986 Nov;18(11):1063-73.

PMID:
3025895
[PubMed - indexed for MEDLINE]
17.

Anti-HIV-1 activity and cellular pharmacology of various analogs of gossypol.

Lin TS, Schinazi RF, Zhu J, Birks E, Carbone R, Si Y, Wu K, Huang L, Prusoff WH.

Biochem Pharmacol. 1993 Jul 20;46(2):251-5.

PMID:
8347147
[PubMed - indexed for MEDLINE]
18.

Cytotoxicity of enantiomers of gossypol Schiff's bases and optical stability of gossypolone.

Dao VT, Dowd MK, Martin MT, Gaspard C, Mayer M, Michelot RJ.

Eur J Med Chem. 2004 Jul;39(7):619-24.

PMID:
15236842
[PubMed - indexed for MEDLINE]
19.

Analogue inhibitors by modifying oseltamivir based on the crystal neuraminidase structure for treating drug-resistant H5N1 virus.

Du QS, Wang SQ, Chou KC.

Biochem Biophys Res Commun. 2007 Oct 19;362(2):525-31. Epub 2007 Aug 13.

PMID:
17707775
[PubMed - indexed for MEDLINE]
20.

Theoretical studies of the interaction between influenza virus hemagglutinin and its small molecule ligands.

Song D, Xu H, Liu S.

J Mol Model. 2013 Dec;19(12):5561-8. doi: 10.1007/s00894-013-2036-0. Epub 2013 Nov 21.

PMID:
24253319
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk