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Items: 1 to 20 of 138

1.

Quantification of the sixth DNA base 5-hydroxymethylcytosine in colorectal cancer tissue and C-26 cell line.

Zhang LT, Zhang LJ, Zhang JJ, Ye XX, Xie AM, Chen LY, Kang JX, Cai C.

Bioanalysis. 2013 Apr;5(7):839-45. doi: 10.4155/bio.13.28.

PMID:
23534428
2.

Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry.

Chen ML, Shen F, Huang W, Qi JH, Wang Y, Feng YQ, Liu SM, Yuan BF.

Clin Chem. 2013 May;59(5):824-32. doi: 10.1373/clinchem.2012.193938. Epub 2013 Jan 23.

3.
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High sensitivity 5-hydroxymethylcytosine detection in Balb/C brain tissue.

Davis T, Vaisvila R.

J Vis Exp. 2011 Feb 1;(48). pii: 2661. doi: 10.3791/2661.

5.

Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation.

Kudo Y, Tateishi K, Yamamoto K, Yamamoto S, Asaoka Y, Ijichi H, Nagae G, Yoshida H, Aburatani H, Koike K.

Cancer Sci. 2012 Apr;103(4):670-6. doi: 10.1111/j.1349-7006.2012.02213.x. Epub 2012 Feb 27.

6.

Hydrophilic material for the selective enrichment of 5-hydroxymethylcytosine and its liquid chromatography-tandem mass spectrometry detection.

Tang Y, Chu JM, Huang W, Xiong J, Xing XW, Zhou X, Feng YQ, Yuan BF.

Anal Chem. 2013 Jun 18;85(12):6129-35. doi: 10.1021/ac4010869. Epub 2013 May 28.

PMID:
23678980
7.

5-hydroxymethylcytosine: a new insight into epigenetics in cancer.

Ye C, Li L.

Cancer Biol Ther. 2014 Jan;15(1):10-5. doi: 10.4161/cbt.27144. Epub 2013 Nov 19. Review.

8.

Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates.

Globisch D, Münzel M, Müller M, Michalakis S, Wagner M, Koch S, Brückl T, Biel M, Carell T.

PLoS One. 2010 Dec 23;5(12):e15367. doi: 10.1371/journal.pone.0015367.

9.

Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.

Bhattacharyya S, Yu Y, Suzuki M, Campbell N, Mazdo J, Vasanthakumar A, Bhagat TD, Nischal S, Christopeit M, Parekh S, Steidl U, Godley L, Maitra A, Greally JM, Verma A.

Nucleic Acids Res. 2013 Sep;41(16):e157. doi: 10.1093/nar/gkt601. Epub 2013 Jul 16.

10.

5-Hydroxymethylcytosine, the sixth base of the genome.

Münzel M, Globisch D, Carell T.

Angew Chem Int Ed Engl. 2011 Jul 11;50(29):6460-8. doi: 10.1002/anie.201101547. Epub 2011 Jun 17. Review.

PMID:
21688365
11.

The role of TET family proteins and 5-hydroxymethylcytosine in human tumors.

Wu YC, Ling ZQ.

Histol Histopathol. 2014 Aug;29(8):991-7. Epub 2014 Feb 28. Review.

PMID:
24585390
12.

Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice.

Chopra P, Papale LA, White AT, Hatch A, Brown RM, Garthwaite MA, Roseboom PH, Golos TG, Warren ST, Alisch RS.

BMC Genomics. 2014 Feb 13;15:131. doi: 10.1186/1471-2164-15-131.

13.

DNA binding of the p21 repressor ZBTB2 is inhibited by cytosine hydroxymethylation.

Lafaye C, Barbier E, Miscioscia A, Saint-Pierre C, Kraut A, Couté Y, Plo I, Gasparutto D, Ravanat JL, Breton J.

Biochem Biophys Res Commun. 2014 Mar 28;446(1):341-6. doi: 10.1016/j.bbrc.2014.02.122. Epub 2014 Mar 4.

PMID:
24607898
14.

The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing.

Huang Y, Pastor WA, Shen Y, Tahiliani M, Liu DR, Rao A.

PLoS One. 2010 Jan 26;5(1):e8888. doi: 10.1371/journal.pone.0008888.

15.

Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors.

Kraus TF, Globisch D, Wagner M, Eigenbrod S, Widmann D, Münzel M, Müller M, Pfaffeneder T, Hackner B, Feiden W, Schüller U, Carell T, Kretzschmar HA.

Int J Cancer. 2012 Oct 1;131(7):1577-90. doi: 10.1002/ijc.27429. Epub 2012 Mar 2.

16.

Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype.

Tsai KW, Li GC, Chen CH, Yeh MH, Huang JS, Tseng HH, Fu TY, Liou HH, Pan HW, Huang SF, Chen CC, Chang HY, Ger LP, Chang HT.

Breast Cancer Res Treat. 2015 Aug;153(1):219-34. doi: 10.1007/s10549-015-3525-x. Epub 2015 Aug 8.

PMID:
26253945
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19.

Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.

Minor EA, Court BL, Young JI, Wang G.

J Biol Chem. 2013 May 10;288(19):13669-74. doi: 10.1074/jbc.C113.464800. Epub 2013 Apr 2.

20.

Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.

Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan G, Chandran S, Hay DC, Bradley M, Wilmut I, De Sousa P.

Cell Res. 2011 Sep;21(9):1332-42. doi: 10.1038/cr.2011.113. Epub 2011 Jul 12.

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