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Results: 1 to 20 of 89

1.

Infiltration of proinflammatory m1 macrophages into the outer retina precedes damage in a mouse model of age-related macular degeneration.

Cruz-Guilloty F, Saeed AM, Echegaray JJ, Duffort S, Ballmick A, Tan Y, Betancourt M, Viteri E, Ramkhellawan GC, Ewald E, Feuer W, Huang D, Wen R, Hong L, Wang H, Laird JM, Sene A, Apte RS, Salomon RG, Hollyfield JG, Perez VL.

Int J Inflam. 2013;2013:503725. doi: 10.1155/2013/503725. Epub 2013 Mar 7.

PMID:
23533946
[PubMed]
Free PMC Article
2.

T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration.

Cruz-Guilloty F, Saeed AM, Duffort S, Cano M, Ebrahimi KB, Ballmick A, Tan Y, Wang H, Laird JM, Salomon RG, Handa JT, Perez VL.

PLoS One. 2014 Feb 19;9(2):e88201. doi: 10.1371/journal.pone.0088201. eCollection 2014.

PMID:
24586307
[PubMed - in process]
Free PMC Article
3.

A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration.

Hollyfield JG, Perez VL, Salomon RG.

Mol Neurobiol. 2010 Jun;41(2-3):290-8. doi: 10.1007/s12035-010-8110-z. Epub 2010 Mar 12.

PMID:
20221855
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Oxidative damage-induced inflammation initiates age-related macular degeneration.

Hollyfield JG, Bonilha VL, Rayborn ME, Yang X, Shadrach KG, Lu L, Ufret RL, Salomon RG, Perez VL.

Nat Med. 2008 Feb;14(2):194-8. doi: 10.1038/nm1709. Epub 2008 Jan 27.

PMID:
18223656
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration.

Gu X, Meer SG, Miyagi M, Rayborn ME, Hollyfield JG, Crabb JW, Salomon RG.

J Biol Chem. 2003 Oct 24;278(43):42027-35. Epub 2003 Aug 15.

PMID:
12923198
[PubMed - indexed for MEDLINE]
Free Article
6.

Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD).

Ramkumar HL, Zhang J, Chan CC.

Prog Retin Eye Res. 2010 May;29(3):169-90. doi: 10.1016/j.preteyeres.2010.02.002. Epub 2010 Mar 3. Review.

PMID:
20206286
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Immunological protein expression profile in Ccl2/Cx3cr1 deficient mice with lesions similar to age-related macular degeneration.

Ross RJ, Zhou M, Shen D, Fariss RN, Ding X, Bojanowski CM, Tuo J, Chan CC.

Exp Eye Res. 2008 Apr;86(4):675-83. doi: 10.1016/j.exer.2008.01.014. Epub 2008 Jan 25.

PMID:
18308304
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Proteoglycans in the mouse interphotoreceptor matrix. III. Changes during photoreceptor development and degeneration in the rds mutant.

Tawara A, Hollyfield JG.

Exp Eye Res. 1990 Sep;51(3):301-15.

PMID:
2119314
[PubMed - indexed for MEDLINE]
9.

Oxidative damage and age-related macular degeneration.

Winkler BS, Boulton ME, Gottsch JD, Sternberg P.

Mol Vis. 1999 Nov 3;5:32. Review.

PMID:
10562656
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model.

Rakoczy PE, Zhang D, Robertson T, Barnett NL, Papadimitriou J, Constable IJ, Lai CM.

Am J Pathol. 2002 Oct;161(4):1515-24.

PMID:
12368224
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

SOD2 knockdown mouse model of early AMD.

Justilien V, Pang JJ, Renganathan K, Zhan X, Crabb JW, Kim SR, Sparrow JR, Hauswirth WW, Lewin AS.

Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4407-20.

PMID:
17898259
[PubMed - indexed for MEDLINE]
Free Article
12.

Age-related retinopathy in NRF2-deficient mice.

Zhao Z, Chen Y, Wang J, Sternberg P, Freeman ML, Grossniklaus HE, Cai J.

PLoS One. 2011 Apr 29;6(4):e19456. doi: 10.1371/journal.pone.0019456.

PMID:
21559389
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Cyclic intensive light exposure induces retinal lesions similar to age-related macular degeneration in APPswe/PS1 bigenic mice.

Dong Z, Li J, Leng Y, Sun X, Hu H, He Y, Tan Z, Ge J.

BMC Neurosci. 2012 Mar 24;13:34. doi: 10.1186/1471-2202-13-34.

PMID:
22443196
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Microglia in the mouse retina alter the structure and function of retinal pigmented epithelial cells: a potential cellular interaction relevant to AMD.

Ma W, Zhao L, Fontainhas AM, Fariss RN, Wong WT.

PLoS One. 2009 Nov 20;4(11):e7945. doi: 10.1371/journal.pone.0007945.

PMID:
19936204
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Retinal degeneration in the nervous mutant mouse. I. Light microscopic cytopathology and changes in the interphotoreceptor matrix.

LaVail MM, White MP, Gorrin GM, Yasumura D, Porrello KV, Mullen RJ.

J Comp Neurol. 1993 Jul 8;333(2):168-81.

PMID:
7688384
[PubMed - indexed for MEDLINE]
16.

Cigarette smoke-related hydroquinone dysregulates MCP-1, VEGF and PEDF expression in retinal pigment epithelium in vitro and in vivo.

Pons M, Marin-CastaƱo ME.

PLoS One. 2011 Feb 28;6(2):e16722. doi: 10.1371/journal.pone.0016722.

PMID:
21386905
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium.

Thampi P, Rao HV, Mitter SK, Cai J, Mao H, Li H, Seo S, Qi X, Lewin AS, Romano C, Boulton ME.

PLoS One. 2012;7(4):e34468. doi: 10.1371/journal.pone.0034468. Epub 2012 Apr 3.

PMID:
22509307
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration.

Hadziahmetovic M, Song Y, Wolkow N, Iacovelli J, Kautz L, Roth MP, Dunaief JL.

Am J Pathol. 2011 Jul;179(1):335-48. doi: 10.1016/j.ajpath.2011.03.033. Epub 2011 May 3.

PMID:
21703414
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The role of oxidative stress in the pathogenesis of age-related macular degeneration.

Beatty S, Koh H, Phil M, Henson D, Boulton M.

Surv Ophthalmol. 2000 Sep-Oct;45(2):115-34. Review.

PMID:
11033038
[PubMed - indexed for MEDLINE]
20.

Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD.

Hadziahmetovic M, Dentchev T, Song Y, Haddad N, He X, Hahn P, Pratico D, Wen R, Harris ZL, Lambris JD, Beard J, Dunaief JL.

Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2728-36. doi: 10.1167/iovs.07-1472. Epub 2008 Mar 7.

PMID:
18326691
[PubMed - indexed for MEDLINE]
Free PMC Article

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