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Results: 1 to 20 of 94

Similar articles for PubMed (Select 23530249)

1.

Family of pH (low) insertion peptides for tumor targeting.

Weerakkody D, Moshnikova A, Thakur MS, Moshnikova V, Daniels J, Engelman DM, Andreev OA, Reshetnyak YK.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5834-9. doi: 10.1073/pnas.1303708110. Epub 2013 Mar 25.

2.

Inhibition of cancer cell proliferation and breast tumor targeting of pHLIP-monomethyl auristatin E conjugates.

Burns KE, Robinson MK, Thévenin D.

Mol Pharm. 2015 Apr 6;12(4):1250-8. doi: 10.1021/mp500779k. Epub 2015 Mar 13.

3.

The negative charge of the membrane has opposite effects on the membrane entry and exit of pH-low insertion peptide.

Scott HL, Nguyen VP, Alves DS, Davis FL, Booth KR, Bryner J, Barrera FN.

Biochemistry. 2015 Mar 10;54(9):1709-12. doi: 10.1021/acs.biochem.5b00069. Epub 2015 Feb 27.

PMID:
25692747
4.

Noncanonical amino acids to improve the pH response of pHLIP insertion at tumor acidity.

Onyango JO, Chung MS, Eng CH, Klees LM, Langenbacher R, Yao L, An M.

Angew Chem Int Ed Engl. 2015 Mar 16;54(12):3658-63. doi: 10.1002/anie.201409770. Epub 2015 Feb 4.

PMID:
25650762
5.

Advanced targeted nanomedicine.

Arachchige MC, Reshetnyak YK, Andreev OA.

J Biotechnol. 2015 May 20;202:88-97. doi: 10.1016/j.jbiotec.2015.01.009. Epub 2015 Jan 20.

PMID:
25615945
6.

Testing the limits of rational design by engineering pH sensitivity into membrane-active peptides.

Wiedman G, Wimley WC, Hristova K.

Biochim Biophys Acta. 2015 Apr;1848(4):951-7. doi: 10.1016/j.bbamem.2014.12.023. Epub 2015 Jan 5.

PMID:
25572997
7.

Targeting acidity in diseased tissues: mechanism and applications of the membrane-inserting peptide, pHLIP.

Deacon JC, Engelman DM, Barrera FN.

Arch Biochem Biophys. 2015 Jan 1;565:40-8. doi: 10.1016/j.abb.2014.11.002. Epub 2014 Nov 18.

PMID:
25444855
8.

pHLIP-FIRE, a cell insertion-triggered fluorescent probe for imaging tumors demonstrates targeted cargo delivery in vivo.

Karabadzhak AG, An M, Yao L, Langenbacher R, Moshnikova A, Adochite RC, Andreev OA, Reshetnyak YK, Engelman DM.

ACS Chem Biol. 2014 Nov 21;9(11):2545-53. doi: 10.1021/cb500388m. Epub 2014 Sep 10.

PMID:
25184440
9.

Targeting breast tumors with pH (low) insertion peptides.

Adochite RC, Moshnikova A, Carlin SD, Guerrieri RA, Andreev OA, Lewis JS, Reshetnyak YK.

Mol Pharm. 2014 Aug 4;11(8):2896-905. doi: 10.1021/mp5002526. Epub 2014 Jul 8.

10.

Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer.

Viola-Villegas NT, Carlin SD, Ackerstaff E, Sevak KK, Divilov V, Serganova I, Kruchevsky N, Anderson M, Blasberg RG, Andreev OA, Engelman DM, Koutcher JA, Reshetnyak YK, Lewis JS.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7254-9. doi: 10.1073/pnas.1405240111. Epub 2014 May 1.

11.

Targeting diseased tissues by pHLIP insertion at low cell surface pH.

Andreev OA, Engelman DM, Reshetnyak YK.

Front Physiol. 2014 Mar 13;5:97. doi: 10.3389/fphys.2014.00097. eCollection 2014. Review.

13.

Tumor cell membrane-targeting pH-dependent electron donor-acceptor fluorescence systems with low background signals.

Han L, Liu M, Ye D, Zhang N, Lim E, Lu J, Jiang C.

Biomaterials. 2014 Mar;35(9):2952-60. doi: 10.1016/j.biomaterials.2013.12.020. Epub 2014 Jan 2.

PMID:
24388814
14.

"To serve and protect": enzyme inhibitors as radiopeptide escorts promote tumor targeting.

Nock BA, Maina T, Krenning EP, de Jong M.

J Nucl Med. 2014 Jan;55(1):121-7. doi: 10.2967/jnumed.113.129411. Epub 2013 Nov 28.

15.

Membrane binding and insertion of a pHLIP peptide studied by all-atom molecular dynamics simulations.

Deng Y, Qian Z, Luo Y, Zhang Y, Mu Y, Wei G.

Int J Mol Sci. 2013 Jul 12;14(7):14532-49. doi: 10.3390/ijms140714532.

16.

Aspartate embedding depth affects pHLIP's insertion pKa.

Fendos J, Barrera FN, Engelman DM.

Biochemistry. 2013 Jul 9;52(27):4595-604. doi: 10.1021/bi400252k. Epub 2013 Jun 27.

17.

pH-controlled delivery of nanoparticles into tumor cells.

Han L, Ma H, Guo Y, Kuang Y, He X, Jiang C.

Adv Healthc Mater. 2013 Nov;2(11):1435-9. doi: 10.1002/adhm.201300013. Epub 2013 Apr 8.

PMID:
23564477
18.

pHLIP®-mediated delivery of PEGylated liposomes to cancer cells.

Yao L, Daniels J, Wijesinghe D, Andreev OA, Reshetnyak YK.

J Control Release. 2013 May 10;167(3):228-37. doi: 10.1016/j.jconrel.2013.01.037. Epub 2013 Feb 15.

19.

Antiproliferative effect of pHLIP-amanitin.

Moshnikova A, Moshnikova V, Andreev OA, Reshetnyak YK.

Biochemistry. 2013 Feb 19;52(7):1171-8. doi: 10.1021/bi301647y. Epub 2013 Feb 8.

20.

pHLIP peptide targets nanogold particles to tumors.

Yao L, Daniels J, Moshnikova A, Kuznetsov S, Ahmed A, Engelman DM, Reshetnyak YK, Andreev OA.

Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):465-70. doi: 10.1073/pnas.1219665110. Epub 2012 Dec 24. Erratum in: Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3651. Danniels, Jennifer [corrected to Daniels, Jennifer].

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