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Results: 1 to 20 of 100

1.

The effects of interleukin-6 signal blockade on immune system, reproductive and skeletal development in juvenile mice.

Sakurai T, Takai R, Bürgin H, Shioda A, Sakamoto Y, Amano J, Grimm HP, Richter WF, Higuchi Y, Chiba S, Kawamura A, Suzuki M, Müller L.

Birth Defects Res B Dev Reprod Toxicol. 2013 Apr;98(2):170-82. doi: 10.1002/bdrb.21053. Epub 2013 Mar 25.

PMID:
23529913
[PubMed - indexed for MEDLINE]
2.

The effects of interleukin-6 signal blockade on fertility, embryo-fetal development, and immunization in vivo.

Sakurai T, Takai R, Bürgin H, Ishihara K, Sakamoto Y, Amano J, Higuchi Y, Chiba S, Singer T, Kawamura A, Suzuki M, Müller L.

Birth Defects Res B Dev Reprod Toxicol. 2012 Aug;95(4):304-17. doi: 10.1002/bdrb.21019. Epub 2012 Jul 5.

PMID:
22767489
[PubMed - indexed for MEDLINE]
3.

Induction of high-dose tolerance to the rat anti-mouse IL-6 receptor antibody in NZB/NZW F1 mice.

Yoshida H, Hashizume M, Suzuki M, Mihara M.

Rheumatol Int. 2011 Nov;31(11):1445-9. doi: 10.1007/s00296-010-1500-8. Epub 2010 May 15.

PMID:
20473503
[PubMed - indexed for MEDLINE]
4.

Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis.

Takagi N, Mihara M, Moriya Y, Nishimoto N, Yoshizaki K, Kishimoto T, Takeda Y, Ohsugi Y.

Arthritis Rheum. 1998 Dec;41(12):2117-21.

PMID:
9870868
[PubMed - indexed for MEDLINE]
6.

IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F1 mice.

Mihara M, Takagi N, Takeda Y, Ohsugi Y.

Clin Exp Immunol. 1998 Jun;112(3):397-402.

PMID:
9649207
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

IL-6 blockade attenuates the development of murine sclerodermatous chronic graft-versus-host disease.

Le Huu D, Matsushita T, Jin G, Hamaguchi Y, Hasegawa M, Takehara K, Fujimoto M.

J Invest Dermatol. 2012 Dec;132(12):2752-61. doi: 10.1038/jid.2012.226. Epub 2012 Jul 19.

PMID:
22810302
[PubMed - indexed for MEDLINE]
Free Article
8.

Characterization of anti-mouse interleukin-6 receptor antibody.

Okazaki M, Yamada Y, Nishimoto N, Yoshizaki K, Mihara M.

Immunol Lett. 2002 Dec 3;84(3):231-40.

PMID:
12413742
[PubMed - indexed for MEDLINE]
9.

Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses.

Fujimoto M, Serada S, Mihara M, Uchiyama Y, Yoshida H, Koike N, Ohsugi Y, Nishikawa T, Ripley B, Kimura A, Kishimoto T, Naka T.

Arthritis Rheum. 2008 Dec;58(12):3710-9. doi: 10.1002/art.24126.

PMID:
19035481
[PubMed - indexed for MEDLINE]
Free Article
10.

Evidence for the role of Th17 cell inhibition in the prevention of autoimmune diseases by anti-interluekin-6 receptor antibody.

Mihara M, Ohsugi Y, Kishimoto T.

Biofactors. 2009 Jan-Feb;35(1):47-51. doi: 10.1002/biof.9. Review.

PMID:
19319845
[PubMed - indexed for MEDLINE]
11.

Therapeutic effects of interleukin-6 blockade in a murine model of polymyositis that does not require interleukin-17A.

Okiyama N, Sugihara T, Iwakura Y, Yokozeki H, Miyasaka N, Kohsaka H.

Arthritis Rheum. 2009 Aug;60(8):2505-12. doi: 10.1002/art.24689.

PMID:
19644888
[PubMed - indexed for MEDLINE]
Free Article
12.

Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase.

Iwanami K, Matsumoto I, Tanaka-Watanabe Y, Inoue A, Mihara M, Ohsugi Y, Mamura M, Goto D, Ito S, Tsutsumi A, Kishimoto T, Sumida T.

Arthritis Rheum. 2008 Mar;58(3):754-63. doi: 10.1002/art.23222.

PMID:
18311788
[PubMed - indexed for MEDLINE]
Free Article
13.

Anti-inflammatory effect of IL-6 receptor blockade in corneal alkali burn.

Sakimoto T, Sugaya S, Ishimori A, Sawa M.

Exp Eye Res. 2012 Apr;97(1):98-104. doi: 10.1016/j.exer.2012.02.015. Epub 2012 Mar 9.

PMID:
22551515
[PubMed - indexed for MEDLINE]
14.

Comparative activity of Sant7 and anti-IL-6, IL-6R monoclonal antibodies in a murine model of B-cell lymphoma.

Campo S, Serlupi-Crescenzi O, Arseni B, Rossi S, Saggio I, Salone B, Cherubini G, Carminati P, De Santis R.

Cytokine. 2005 Sep 7;31(5):368-74.

PMID:
16061391
[PubMed - indexed for MEDLINE]
15.

Blockade of interleukin-6 signaling suppresses experimental autoimmune uveoretinitis by the inhibition of inflammatory Th17 responses.

Hohki S, Ohguro N, Haruta H, Nakai K, Terabe F, Serada S, Fujimoto M, Nomura S, Kawahata H, Kishimoto T, Naka T.

Exp Eye Res. 2010 Aug;91(2):162-70. doi: 10.1016/j.exer.2010.04.009. Epub 2010 Apr 24.

PMID:
20420831
[PubMed - indexed for MEDLINE]
16.

Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo.

Axmann R, Böhm C, Krönke G, Zwerina J, Smolen J, Schett G.

Arthritis Rheum. 2009 Sep;60(9):2747-56. doi: 10.1002/art.24781.

PMID:
19714627
[PubMed - indexed for MEDLINE]
Free Article
17.

Anti-interleukin 6 receptor antibody inhibits murine AA-amyloidosis.

Mihara M, Shiina M, Nishimoto N, Yoshizaki K, Kishimoto T, Akamatsu K.

J Rheumatol. 2004 Jun;31(6):1132-8.

PMID:
15170926
[PubMed - indexed for MEDLINE]
18.

Influences of anti-mouse interleukin-6 receptor antibody on immune responses in mice.

Mihara M, Nishimoto N, Yoshizaki K, Suzuki T.

Immunol Lett. 2002 Dec 3;84(3):223-9.

PMID:
12413741
[PubMed - indexed for MEDLINE]
19.

The therapy of autoimmune diseases by anti-interleukin-6 receptor antibody.

Mihara M, Nishimoto N, Ohsugi Y.

Expert Opin Biol Ther. 2005 May;5(5):683-90. Review.

PMID:
15934843
[PubMed - indexed for MEDLINE]
20.

Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice.

Guerrero AR, Uchida K, Nakajima H, Watanabe S, Nakamura M, Johnson WE, Baba H.

J Neuroinflammation. 2012 Feb 27;9:40. doi: 10.1186/1742-2094-9-40.

PMID:
22369693
[PubMed - indexed for MEDLINE]
Free PMC Article

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