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Results: 1 to 20 of 108

1.

Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II.

Shi J, Geshi N, Takahashi S, Kiyonaka S, Ichikawa J, Hu Y, Mori Y, Ito Y, Inoue R.

J Physiol. 2013 Jun 1;591(Pt 11):2851-66. doi: 10.1113/jphysiol.2013.251249. Epub 2013 Mar 25.

PMID:
23529130
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6.

Takahashi S, Lin H, Geshi N, Mori Y, Kawarabayashi Y, Takami N, Mori MX, Honda A, Inoue R.

J Physiol. 2008 Sep 1;586(Pt 17):4209-23. doi: 10.1113/jphysiol.2008.156083. Epub 2008 Jul 10.

PMID:
18617565
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Multiple regulation by calcium of murine homologues of transient receptor potential proteins TRPC6 and TRPC7 expressed in HEK293 cells.

Shi J, Mori E, Mori Y, Mori M, Li J, Ito Y, Inoue R.

J Physiol. 2004 Dec 1;561(Pt 2):415-32. Epub 2004 Oct 7.

PMID:
15579537
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Protein kinase C-dependent phosphorylation of transient receptor potential canonical 6 (TRPC6) on serine 448 causes channel inhibition.

Bousquet SM, Monet M, Boulay G.

J Biol Chem. 2010 Dec 24;285(52):40534-43. doi: 10.1074/jbc.M110.160051. Epub 2010 Oct 20.

PMID:
20961851
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Function and regulation of endothelin type A receptor-operated transient receptor potential canonical channels.

Horinouchi T, Terada K, Higa T, Aoyagi H, Nishiya T, Suzuki H, Miwa S.

J Pharmacol Sci. 2011;117(4):295-306. Epub 2011 Dec 1.

PMID:
22129540
[PubMed - indexed for MEDLINE]
Free Article
6.

The interactions of the C-terminal region of the TRPC6 channel with calmodulin.

Friedlova E, Grycova L, Holakovska B, Silhan J, Janouskova H, Sulc M, Obsilova V, Obsil T, Teisinger J.

Neurochem Int. 2010 Jan;56(2):363-6. doi: 10.1016/j.neuint.2009.11.009. Epub 2009 Nov 20.

PMID:
19932145
[PubMed - indexed for MEDLINE]
7.

Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells.

Soboloff J, Spassova M, Xu W, He LP, Cuesta N, Gill DL.

J Biol Chem. 2005 Dec 2;280(48):39786-94. Epub 2005 Oct 3.

PMID:
16204251
[PubMed - indexed for MEDLINE]
Free Article
8.

Functional role of the calmodulin- and inositol 1,4,5-trisphosphate receptor-binding (CIRB) site of TRPC6 in human platelet activation.

Dionisio N, Albarran L, Berna-Erro A, Hernandez-Cruz JM, Salido GM, Rosado JA.

Cell Signal. 2011 Nov;23(11):1850-6. doi: 10.1016/j.cellsig.2011.06.022. Epub 2011 Jul 3.

PMID:
21757000
[PubMed - indexed for MEDLINE]
9.

Synergistic activation of vascular TRPC6 channel by receptor and mechanical stimulation via phospholipase C/diacylglycerol and phospholipase A2/omega-hydroxylase/20-HETE pathways.

Inoue R, Jensen LJ, Jian Z, Shi J, Hai L, Lurie AI, Henriksen FH, Salomonsson M, Morita H, Kawarabayashi Y, Mori M, Mori Y, Ito Y.

Circ Res. 2009 Jun 19;104(12):1399-409. doi: 10.1161/CIRCRESAHA.108.193227. Epub 2009 May 14.

PMID:
19443836
[PubMed - indexed for MEDLINE]
Free Article
10.

Involvement of phosphoinositide 3-kinase and PTEN protein in mechanism of activation of TRPC6 protein in vascular smooth muscle cells.

Monet M, Francoeur N, Boulay G.

J Biol Chem. 2012 May 18;287(21):17672-81. doi: 10.1074/jbc.M112.341354. Epub 2012 Apr 5.

PMID:
22493444
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Na+ channel regulation by Ca2+/calmodulin and Ca2+/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes.

Aiba T, Hesketh GG, Liu T, Carlisle R, Villa-Abrille MC, O'Rourke B, Akar FG, Tomaselli GF.

Cardiovasc Res. 2010 Feb 1;85(3):454-63. doi: 10.1093/cvr/cvp324. Epub 2009 Oct 1.

PMID:
19797425
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription.

Schlöndorff J, Del Camino D, Carrasquillo R, Lacey V, Pollak MR.

Am J Physiol Cell Physiol. 2009 Mar;296(3):C558-69. doi: 10.1152/ajpcell.00077.2008. Epub 2009 Jan 7.

PMID:
19129465
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2).

Chiluiza D, Krishna S, Schumacher VA, Schlöndorff J.

J Biol Chem. 2013 Jun 21;288(25):18407-20. doi: 10.1074/jbc.M113.463059. Epub 2013 May 3.

PMID:
23645677
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites.

Ashpole NM, Herren AW, Ginsburg KS, Brogan JD, Johnson DE, Cummins TR, Bers DM, Hudmon A.

J Biol Chem. 2012 Jun 8;287(24):19856-69. doi: 10.1074/jbc.M111.322537. Epub 2012 Apr 18.

PMID:
22514276
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Molecular determinants of PKA-dependent inhibition of TRPC5 channel.

Sung TS, Jeon JP, Kim BJ, Hong C, Kim SY, Kim J, Jeon JH, Kim HJ, Suh CK, Kim SJ, So I.

Am J Physiol Cell Physiol. 2011 Oct;301(4):C823-32. doi: 10.1152/ajpcell.00351.2010. Epub 2011 Jul 6.

PMID:
21734191
[PubMed - indexed for MEDLINE]
Free Article
16.

A calmodulin/inositol 1,4,5-trisphosphate (IP3) receptor-binding region targets TRPC3 to the plasma membrane in a calmodulin/IP3 receptor-independent process.

Wedel BJ, Vazquez G, McKay RR, St J Bird G, Putney JW Jr.

J Biol Chem. 2003 Jul 11;278(28):25758-65. Epub 2003 May 2.

PMID:
12730194
[PubMed - indexed for MEDLINE]
Free Article
17.

Cilostazol suppresses angiotensin II-induced vasoconstriction via protein kinase A-mediated phosphorylation of the transient receptor potential canonical 6 channel.

Nishioka K, Nishida M, Ariyoshi M, Jian Z, Saiki S, Hirano M, Nakaya M, Sato Y, Kita S, Iwamoto T, Hirano K, Inoue R, Kurose H.

Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2278-86. doi: 10.1161/ATVBAHA.110.221010. Epub 2011 Jul 28.

PMID:
21799177
[PubMed - indexed for MEDLINE]
Free Article
18.

C terminus L-type Ca2+ channel calmodulin-binding domains are 'auto-agonist' ligands in rabbit ventricular myocytes.

Dzhura I, Wu Y, Zhang R, Colbran RJ, Hamilton SL, Anderson ME.

J Physiol. 2003 Aug 1;550(Pt 3):731-8. Epub 2003 Jun 13.

PMID:
12807986
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease.

Kistler AD, Singh G, Altintas MM, Yu H, Fernandez IC, Gu C, Wilson C, Srivastava SK, Dietrich A, Walz K, Kerjaschki D, Ruiz P, Dryer S, Sever S, Dinda AK, Faul C, Reiser J.

J Biol Chem. 2013 Dec 20;288(51):36598-609. doi: 10.1074/jbc.M113.488122. Epub 2013 Nov 5.

PMID:
24194522
[PubMed - indexed for MEDLINE]
20.

Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6.

Kwon Y, Hofmann T, Montell C.

Mol Cell. 2007 Feb 23;25(4):491-503.

PMID:
17317623
[PubMed - indexed for MEDLINE]
Free PMC Article

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