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Results: 1 to 20 of 101

1.

Association of UGT1A1*28 polymorphisms with irinotecan-induced toxicities in colorectal cancer: a meta-analysis in Caucasians.

Liu X, Cheng D, Kuang Q, Liu G, Xu W.

Pharmacogenomics J. 2014 Apr;14(2):120-9. doi: 10.1038/tpj.2013.10. Epub 2013 Mar 26.

PMID:
23529007
[PubMed - in process]
Free PMC Article
2.

UGT1A1*6 polymorphisms are correlated with irinotecan-induced toxicity: a system review and meta-analysis in Asians.

Cheng L, Li M, Hu J, Ren W, Xie L, Sun ZP, Liu BR, Xu GX, Dong XL, Qian XP.

Cancer Chemother Pharmacol. 2014 Mar;73(3):551-60. doi: 10.1007/s00280-014-2382-3. Epub 2014 Jan 22.

PMID:
24448639
[PubMed - in process]
3.

Association between UGT1A1*28 polymorphisms and clinical outcomes of irinotecan-based chemotherapies in colorectal cancer: a meta-analysis in Caucasians.

Liu X, Cheng D, Kuang Q, Liu G, Xu W.

PLoS One. 2013;8(3):e58489. doi: 10.1371/journal.pone.0058489. Epub 2013 Mar 14.

PMID:
23516488
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Dose-dependent association between UGT1A1*28 polymorphism and irinotecan-induced diarrhoea: a meta-analysis.

Hu ZY, Yu Q, Zhao YS.

Eur J Cancer. 2010 Jul;46(10):1856-65. doi: 10.1016/j.ejca.2010.02.049. Epub 2010 Mar 23. Review.

PMID:
20335017
[PubMed - indexed for MEDLINE]
5.

Associations between UGT1A1*6 or UGT1A1*6/*28 polymorphisms and irinotecan-induced neutropenia in Asian cancer patients.

Han FF, Guo CL, Yu D, Zhu J, Gong LL, Li GR, Lv YL, Liu H, An GY, Liu LH.

Cancer Chemother Pharmacol. 2014 Apr;73(4):779-88. doi: 10.1007/s00280-014-2405-0. Epub 2014 Feb 12.

PMID:
24519753
[PubMed - in process]
6.

Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? An evidence-based review.

Palomaki GE, Bradley LA, Douglas MP, Kolor K, Dotson WD.

Genet Med. 2009 Jan;11(1):21-34. doi: 10.1097/GIM.0b013e31818efd77. Review.

PMID:
19125129
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters.

Hoskins JM, Goldberg RM, Qu P, Ibrahim JG, McLeod HL.

J Natl Cancer Inst. 2007 Sep 5;99(17):1290-5. Epub 2007 Aug 28.

PMID:
17728214
[PubMed - indexed for MEDLINE]
Free Article
8.

UGT1A1 gene variations and irinotecan treatment in patients with metastatic colorectal cancer.

Marcuello E, Altés A, Menoyo A, Del Rio E, Gómez-Pardo M, Baiget M.

Br J Cancer. 2004 Aug 16;91(4):678-82.

PMID:
15280927
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

UGT1A1 gene polymorphisms and the toxicities of FOLFIRI in Chinese Han patients with gastrointestinal cancer.

Zhou CF, Ma T, Su Y, Ye ZB, Ji J, Yu YY, Zhang J, Liu BY, Zhu ZG.

Anticancer Agents Med Chem. 2013 Feb;13(2):235-41.

PMID:
22934695
[PubMed - indexed for MEDLINE]
10.

UGT1A1*28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma.

Liu CY, Chen PM, Chiou TJ, Liu JH, Lin JK, Lin TC, Chen WS, Jiang JK, Wang HS, Wang WS.

Cancer. 2008 May 1;112(9):1932-40. doi: 10.1002/cncr.23370.

PMID:
18300238
[PubMed - indexed for MEDLINE]
Free Article
11.

Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis.

Ando Y, Saka H, Ando M, Sawa T, Muro K, Ueoka H, Yokoyama A, Saitoh S, Shimokata K, Hasegawa Y.

Cancer Res. 2000 Dec 15;60(24):6921-6.

PMID:
11156391
[PubMed - indexed for MEDLINE]
Free Article
12.

[Study of irinotecan-induced toxicity and its correlation to UGT1A1 gene promoter polymorphisms].

Li H, Huang H, Liu JH.

Zhonghua Fu Chan Ke Za Zhi. 2011 Dec;46(12):888-91. Chinese.

PMID:
22333276
[PubMed - in process]
13.

Dose-dependent association between UGT1A1*28 genotype and irinotecan-induced neutropenia: low doses also increase risk.

Hu ZY, Yu Q, Pei Q, Guo C.

Clin Cancer Res. 2010 Aug 1;16(15):3832-42. doi: 10.1158/1078-0432.CCR-10-1122. Epub 2010 Jun 18.

PMID:
20562211
[PubMed - indexed for MEDLINE]
Free Article
14.

A genotype-directed phase I-IV dose-finding study of irinotecan in combination with fluorouracil/leucovorin as first-line treatment in advanced colorectal cancer.

Marcuello E, Páez D, Paré L, Salazar J, Sebio A, del Rio E, Baiget M.

Br J Cancer. 2011 Jun 28;105(1):53-7. doi: 10.1038/bjc.2011.206. Epub 2011 Jun 7.

PMID:
21654688
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Associations between UGT1A1*6/*28 polymorphisms and irinotecan-induced severe toxicity in Chinese gastric or esophageal cancer patients.

Gao J, Zhou J, Li Y, Peng Z, Li Y, Wang X, Shen L.

Med Oncol. 2013;30(3):630. doi: 10.1007/s12032-013-0630-8. Epub 2013 Jun 20.

PMID:
23783485
[PubMed - indexed for MEDLINE]
16.

UGT1A1*6, 1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI-treated metastatic colorectal cancer in two prospective studies in Japan.

Hazama S, Mishima H, Tsunedomi R, Okuyama Y, Kato T, Takahashi K, Nozawa H, Ando H, Kobayashi M, Takemoto H, Nagata N, Kanekiyo S, Inoue Y, Hamamoto Y, Fujita Y, Hinoda Y, Okayama N, Oba K, Sakamoto J, Oka M.

Cancer Sci. 2013 Dec;104(12):1662-9. doi: 10.1111/cas.12283. Epub 2013 Oct 27.

PMID:
24033692
[PubMed - indexed for MEDLINE]
17.

UGT1A1 6/28 polymorphisms could predict irinotecan-induced severe neutropenia not diarrhea in Chinese colorectal cancer patients.

Gao J, Zhou J, Li Y, Lu M, Jia R, Shen L.

Med Oncol. 2013;30(3):604. doi: 10.1007/s12032-013-0604-x. Epub 2013 May 18.

PMID:
23686699
[PubMed - indexed for MEDLINE]
18.

Increased frequency of uridine diphosphate glucuronosyltransferase 1A1 7/7 in patients experiencing severe irinotecan-induced toxicities.

Fakih MG, Ross ME, Starostik P.

Clin Colorectal Cancer. 2007 Jul;6(8):583-7.

PMID:
17681105
[PubMed - indexed for MEDLINE]
19.

Recommendations from the EGAPP Working Group: can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan?

Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group.

Genet Med. 2009 Jan;11(1):15-20. doi: 10.1097/GIM.0b013e31818efd9d.

PMID:
19125128
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy.

Martinez-Balibrea E, Abad A, Martínez-Cardús A, Ginés A, Valladares M, Navarro M, Aranda E, Marcuello E, Benavides M, Massutí B, Carrato A, Layos L, Manzano JL, Moreno V.

Br J Cancer. 2010 Aug 10;103(4):581-9. doi: 10.1038/sj.bjc.6605776. Epub 2010 Jul 13.

PMID:
20628391
[PubMed - indexed for MEDLINE]
Free PMC Article

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