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Results: 1 to 20 of 106

1.

The anti-melanoma activity of dinaciclib, a cyclin-dependent kinase inhibitor, is dependent on p53 signaling.

Desai BM, Villanueva J, Nguyen TT, Lioni M, Xiao M, Kong J, Krepler C, Vultur A, Flaherty KT, Nathanson KL, Smalley KS, Herlyn M.

PLoS One. 2013;8(3):e59588. doi: 10.1371/journal.pone.0059588. Epub 2013 Mar 18.

PMID:
23527225
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The cyclin-dependent kinase inhibitor SCH 727965 (dinacliclib) induces the apoptosis of osteosarcoma cells.

Fu W, Ma L, Chu B, Wang X, Bui MM, Gemmer J, Altiok S, Pledger WJ.

Mol Cancer Ther. 2011 Jun;10(6):1018-27. doi: 10.1158/1535-7163.MCT-11-0167. Epub 2011 Apr 13.

PMID:
21490307
[PubMed - indexed for MEDLINE]
Free Article
3.

Vinblastine sensitizes leukemia cells to cyclin-dependent kinase inhibitors, inducing acute cell cycle phase-independent apoptosis.

Bates DJ, Salerni BL, Lowrey CH, Eastman A.

Cancer Biol Ther. 2011 Aug 15;12(4):314-25. Epub 2011 Aug 15.

PMID:
21768777
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models.

Feldmann G, Mishra A, Bisht S, Karikari C, Garrido-Laguna I, Rasheed Z, Ottenhof NA, Dadon T, Alvarez H, Fendrich V, Rajeshkumar NV, Matsui W, Brossart P, Hidalgo M, Bannerji R, Maitra A, Nelkin BD.

Cancer Biol Ther. 2011 Oct 1;12(7):598-609. Epub 2011 Oct 1.

PMID:
21768779
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Differential modulatory effects of GSK-3β and HDM2 on sorafenib-induced AIF nuclear translocation (programmed necrosis) in melanoma.

Liu Q, Mier JW, Panka DJ.

Mol Cancer. 2011 Sep 19;10:115. doi: 10.1186/1476-4598-10-115.

PMID:
21929745
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.

Shin DY, Sung Kang H, Kim GY, Kim WJ, Yoo YH, Choi YH.

Biomed Pharmacother. 2013 May;67(4):305-11. doi: 10.1016/j.biopha.2013.01.004. Epub 2013 Feb 14.

PMID:
23582784
[PubMed - indexed for MEDLINE]
7.

Xylocydine, a novel Cdk inhibitor, is an effective inducer of apoptosis in hepatocellular carcinoma cells in vitro and in vivo.

Cho SJ, Lee SS, Kim YJ, Park BD, Choi JS, Liu L, Ham YM, Moon Kim B, Lee SK.

Cancer Lett. 2010 Jan 28;287(2):196-206. doi: 10.1016/j.canlet.2009.06.011. Epub 2009 Jul 17.

PMID:
19616371
[PubMed - indexed for MEDLINE]
8.
9.

Sodium ascorbate inhibits growth via the induction of cell cycle arrest and apoptosis in human malignant melanoma A375.S2 cells.

Lin SY, Lai WW, Chou CC, Kuo HM, Li TM, Chung JG, Yang JH.

Melanoma Res. 2006 Dec;16(6):509-19.

PMID:
17119452
[PubMed - indexed for MEDLINE]
10.
11.

Biological evaluation of MR36, a novel non-polyglutamatable thymidylate synthase inhibitor that blocks cell cycle progression in melanoma cell lines.

Giudice S, Benassi L, Bertazzoni G, Veratti E, Morini D, Azzoni P, Costi MP, Venturelli A, Pirondi S, Seidenari S, Magnoni C.

Invest New Drugs. 2012 Aug;30(4):1484-92. doi: 10.1007/s10637-011-9733-2. Epub 2011 Sep 1.

PMID:
21881917
[PubMed - indexed for MEDLINE]
12.

Inhibition of urokinase-type plasminogen activator receptor induces apoptosis in melanoma cells by activation of p53.

Besch R, Berking C, Kammerbauer C, Degitz K.

Cell Death Differ. 2007 Apr;14(4):818-29. Epub 2006 Nov 17.

PMID:
17110957
[PubMed - indexed for MEDLINE]
Free Article
13.

TGF-beta-mediated cell cycle arrest of HPV16-immortalized human ectocervical cells correlates with decreased E6/E7 mRNA and increased p53 and p21(WAF-1) expression.

Rorke EA, Zhang D, Choo CK, Eckert RL, Jacobberger JW.

Exp Cell Res. 2000 Aug 25;259(1):149-57.

PMID:
10942587
[PubMed - indexed for MEDLINE]
14.

Effector mechanisms of norcantharidin-induced mitotic arrest and apoptosis in human hepatoma cells.

Chen YN, Chen JC, Yin SC, Wang GS, Tsauer W, Hsu SF, Hsu SL.

Int J Cancer. 2002 Jul 10;100(2):158-65.

PMID:
12115564
[PubMed - indexed for MEDLINE]
15.

Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.

Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.

J Agric Food Chem. 2012 Jan 18;60(2):665-75. doi: 10.1021/jf204193v. Epub 2012 Jan 6.

PMID:
22148415
[PubMed - indexed for MEDLINE]
16.

Caffeic acid phenethyl ester suppresses melanoma tumor growth by inhibiting PI3K/AKT/XIAP pathway.

Pramanik KC, Kudugunti SK, Fofaria NM, Moridani MY, Srivastava SK.

Carcinogenesis. 2013 Sep;34(9):2061-70. doi: 10.1093/carcin/bgt154. Epub 2013 May 2.

PMID:
23640046
[PubMed - indexed for MEDLINE]
17.

Phenoxodiol, a novel isoflavone, induces G1 arrest by specific loss in cyclin-dependent kinase 2 activity by p53-independent induction of p21WAF1/CIP1.

Aguero MF, Facchinetti MM, Sheleg Z, Senderowicz AM.

Cancer Res. 2005 Apr 15;65(8):3364-73.

PMID:
15833870
[PubMed - indexed for MEDLINE]
Free Article
18.

Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells.

Jiang XH, Wong BC, Lin MC, Zhu GH, Kung HF, Jiang SH, Yang D, Lam SK.

Oncogene. 2001 Nov 29;20(55):8009-18.

PMID:
11753684
[PubMed - indexed for MEDLINE]
Free Article
19.

In vitro and in vivo activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials.

DePinto W, Chu XJ, Yin X, Smith M, Packman K, Goelzer P, Lovey A, Chen Y, Qian H, Hamid R, Xiang Q, Tovar C, Blain R, Nevins T, Higgins B, Luistro L, Kolinsky K, Felix B, Hussain S, Heimbrook D.

Mol Cancer Ther. 2006 Nov;5(11):2644-58.

PMID:
17121911
[PubMed - indexed for MEDLINE]
Free Article
20.

Cell cycle arrest and apoptosis of melanoma cells by docosahexaenoic acid: association with decreased pRb phosphorylation.

Albino AP, Juan G, Traganos F, Reinhart L, Connolly J, Rose DP, Darzynkiewicz Z.

Cancer Res. 2000 Aug 1;60(15):4139-45.

PMID:
10945621
[PubMed - indexed for MEDLINE]
Free Article

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