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Results: 1 to 20 of 100

1.

Identification of a small molecule activator of SIRT1 gene expression.

Cho SY, Cho M, Seo DB, Lee SJ, Suh Y.

Aging (Albany NY). 2013 Mar;5(3):174-82.

PMID:
23525956
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells.

Jia Y, Gao P, Chen H, Wan Y, Zhang R, Zhang Z, Yang R, Wang X, Xu J, Liu D.

Sci China Life Sci. 2013 Jan;56(1):19-25. doi: 10.1007/s11427-012-4407-7. Epub 2012 Dec 12.

PMID:
23238746
[PubMed - indexed for MEDLINE]
3.

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice.

Yao H, Chung S, Hwang JW, Rajendrasozhan S, Sundar IK, Dean DA, McBurney MW, Guarente L, Gu W, Rönty M, Kinnula VL, Rahman I.

J Clin Invest. 2012 Jun 1;122(6):2032-45. doi: 10.1172/JCI60132. Epub 2012 May 1.

PMID:
22546858
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Measles virus nucleocapsid protein, a key contributor to Paget's disease, increases IL-6 expression via down-regulation of FoxO3/Sirt1 signaling.

Wang FM, Sarmasik A, Hiruma Y, Sun Q, Sammut B, Windle JJ, Roodman GD, Galson DL.

Bone. 2013 Mar;53(1):269-76. doi: 10.1016/j.bone.2012.12.007. Epub 2012 Dec 20.

PMID:
23262029
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Resveratrol protects human endothelium from H(2)O(2)-induced oxidative stress and senescence via SirT1 activation.

Kao CL, Chen LK, Chang YL, Yung MC, Hsu CC, Chen YC, Lo WL, Chen SJ, Ku HH, Hwang SJ.

J Atheroscler Thromb. 2010 Sep 30;17(9):970-9. Epub 2010 Jul 13.

PMID:
20644332
[PubMed - indexed for MEDLINE]
Free Article
6.

Ginkgolide B reduces LOX-1 expression by inhibiting Akt phosphorylation and increasing Sirt1 expression in oxidized LDL-stimulated human umbilical vein endothelial cells.

Ma L, Liu X, Zhao Y, Chen B, Li X, Qi R.

PLoS One. 2013 Sep 17;8(9):e74769. doi: 10.1371/journal.pone.0074769. eCollection 2013.

PMID:
24069345
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

SIRT1 prevents replicative senescence of normal human umbilical cord fibroblast through potentiating the transcription of human telomerase reverse transcriptase gene.

Yamashita S, Ogawa K, Ikei T, Udono M, Fujiki T, Katakura Y.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):630-4. doi: 10.1016/j.bbrc.2011.12.021. Epub 2011 Dec 14.

PMID:
22197555
[PubMed - indexed for MEDLINE]
8.

Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation.

Wang F, Chan CH, Chen K, Guan X, Lin HK, Tong Q.

Oncogene. 2012 Mar 22;31(12):1546-57. doi: 10.1038/onc.2011.347. Epub 2011 Aug 15.

PMID:
21841822
[PubMed - indexed for MEDLINE]
9.

Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol.

Xia N, Strand S, Schlufter F, Siuda D, Reifenberg G, Kleinert H, Förstermann U, Li H.

Nitric Oxide. 2013 Aug 1;32:29-35. doi: 10.1016/j.niox.2013.04.001. Epub 2013 Apr 10.

PMID:
23583951
[PubMed - indexed for MEDLINE]
10.

Sirtuin 1 stabilization by HuR represses TNF-α- and glucose-induced E-selectin release and endothelial cell adhesiveness in vitro: relevance to human metabolic syndrome.

Ceolotto G, De Kreutzenberg SV, Cattelan A, Fabricio AS, Squarcina E, Gion M, Semplicini A, Fadini GP, Avogaro A.

Clin Sci (Lond). 2014 Oct;127(7):449-61. doi: 10.1042/CS20130439.

PMID:
24702436
[PubMed - indexed for MEDLINE]
11.

Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1.

Arunachalam G, Samuel SM, Marei I, Ding H, Triggle CR.

Br J Pharmacol. 2014 Jan;171(2):523-35. doi: 10.1111/bph.12496.

PMID:
24372553
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Analysis of sirtuin 1 expression reveals a molecular explanation of IL-2-mediated reversal of T-cell tolerance.

Gao B, Kong Q, Kemp K, Zhao YS, Fang D.

Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):899-904. doi: 10.1073/pnas.1118462109. Epub 2012 Jan 4.

PMID:
22219356
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Docosahexaenoic acid improves vascular function via up-regulation of SIRT1 expression in endothelial cells.

Jung SB, Kwon SK, Kwon M, Nagar H, Jeon BH, Irani K, Yoon SH, Kim CS.

Biochem Biophys Res Commun. 2013 Jul 19;437(1):114-9. doi: 10.1016/j.bbrc.2013.06.049. Epub 2013 Jun 24.

PMID:
23806688
[PubMed - indexed for MEDLINE]
14.

FoxO1 mediates an autofeedback loop regulating SIRT1 expression.

Xiong S, Salazar G, Patrushev N, Alexander RW.

J Biol Chem. 2011 Feb 18;286(7):5289-99. doi: 10.1074/jbc.M110.163667. Epub 2010 Dec 13.

PMID:
21149440
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Induction of hypothalamic Sirt1 leads to cessation of feeding via agouti-related peptide.

Sasaki T, Kim HJ, Kobayashi M, Kitamura YI, Yokota-Hashimoto H, Shiuchi T, Minokoshi Y, Kitamura T.

Endocrinology. 2010 Jun;151(6):2556-66. doi: 10.1210/en.2009-1319. Epub 2010 Apr 7.

PMID:
20375183
[PubMed - indexed for MEDLINE]
16.

PPARbeta/delta regulates the human SIRT1 gene transcription via Sp1.

Okazaki M, Iwasaki Y, Nishiyama M, Taguchi T, Tsugita M, Nakayama S, Kambayashi M, Hashimoto K, Terada Y.

Endocr J. 2010;57(5):403-13. Epub 2010 Feb 17.

PMID:
20160399
[PubMed - indexed for MEDLINE]
Free Article
17.

FoxO-dependent and -independent mechanisms mediate SirT1 effects on IGFBP-1 gene expression.

Gan L, Han Y, Bastianetto S, Dumont Y, Unterman TG, Quirion R.

Biochem Biophys Res Commun. 2005 Dec 2;337(4):1092-6. Epub 2005 Oct 5.

PMID:
16236254
[PubMed - indexed for MEDLINE]
18.

Alteration of forkhead box O (foxo4) acetylation mediates apoptosis of podocytes in diabetes mellitus.

Chuang PY, Dai Y, Liu R, He H, Kretzler M, Jim B, Cohen CD, He JC.

PLoS One. 2011;6(8):e23566. doi: 10.1371/journal.pone.0023566. Epub 2011 Aug 17.

PMID:
21858169
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The protective effect of fenofibrate against TNF-α-induced CD40 expression through SIRT1-mediated deacetylation of NF-κB in endothelial cells.

Wang W, Bai L, Qiao H, Lu Y, Yang L, Zhang J, Lin R, Ren F, Zhang J, Ji M.

Inflammation. 2014 Feb;37(1):177-85.

PMID:
24022598
[PubMed - indexed for MEDLINE]
20.

Testosterone deficiency accelerates neuronal and vascular aging of SAMP8 mice: protective role of eNOS and SIRT1.

Ota H, Akishita M, Akiyoshi T, Kahyo T, Setou M, Ogawa S, Iijima K, Eto M, Ouchi Y.

PLoS One. 2012;7(1):e29598. doi: 10.1371/journal.pone.0029598. Epub 2012 Jan 4.

PMID:
22238626
[PubMed - indexed for MEDLINE]
Free PMC Article

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