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Items: 1 to 20 of 104

1.

Potent fibrinolysis inhibitor discovered by shape and electrostatic complementarity to the drug tranexamic acid.

Boström J, Grant JA, Fjellström O, Thelin A, Gustafsson D.

J Med Chem. 2013 Apr 25;56(8):3273-80. doi: 10.1021/jm301818g. Epub 2013 Apr 10.

PMID:
23521080
2.

Desmoteplase-mediated plasminogen activation and clot lysis are inhibited by the lysine analogue tranexamic acid.

Niego B, Horvath A, Coughlin PB, Pugsley MK, Medcalf RL.

Blood Coagul Fibrinolysis. 2008 Jun;19(4):322-4. doi: 10.1097/MBC.0b013e3282f54568. No abstract available.

PMID:
18469556
3.
4.

Temporally and regionally disparate differences in plasmin activity by tranexamic acid.

Reust DL, Reeves ST, Abernathy JH 3rd, Dixon JA, Gaillard WF 2nd, Mukherjee R, Koval CN, Stroud RE, Spinale FG.

Anesth Analg. 2010 Mar 1;110(3):694-701. doi: 10.1213/ANE.0b013e3181c7eb27.

5.

Tranexamic acid combined with recombinant factor VIII increases clot resistance to accelerated fibrinolysis in severe hemophilia A.

Hvas AM, Sørensen HT, Norengaard L, Christiansen K, Ingerslev J, Sørensen B.

J Thromb Haemost. 2007 Dec;5(12):2408-14. Epub 2007 Sep 6.

6.
7.

Tranexamic acid: a novel oral formulation for the treatment of heavy menstrual bleeding.

Lukes AS, Kouides PA, Moore KA.

Womens Health (Lond Engl). 2011 Mar;7(2):151-8. doi: 10.2217/whe.11.9. Review.

PMID:
21410342
8.

The effect of tranexamic acid on local and plasma fibrinolysis during total knee arthroplasty.

Benoni G, Lethagen S, Fredin H.

Thromb Res. 1997 Feb 1;85(3):195-206. Erratum in: hromb Res 1997 Oct 15;88(2):251.

PMID:
9058494
9.

Studies on the mechanism of the antifibrinolytic action of tranexamic acid.

Hoylaerts M, Lijnen HR, Collen D.

Biochim Biophys Acta. 1981 Feb 18;673(1):75-85. No abstract available.

PMID:
7193484
10.

Engineering kunitz domain 1 (KD1) of human tissue factor pathway inhibitor-2 to selectively inhibit fibrinolysis: properties of KD1-L17R variant.

Bajaj MS, Ogueli GI, Kumar Y, Vadivel K, Lawson G, Shanker S, Schmidt AE, Bajaj SP.

J Biol Chem. 2011 Feb 11;286(6):4329-40. doi: 10.1074/jbc.M110.191163. Epub 2010 Nov 29.

11.

Systematic elucidation of effects of tranexamic acid on fibrinolysis and bleeding during and after cardiopulmonary bypass surgery.

Kojima T, Gando S, Morimoto Y, Mashio H, Goda Y, Kawahigashi H, Kemmotsu O.

Thromb Res. 2001 Dec 1;104(5):301-7.

PMID:
11738071
12.

Factor XIII and tranexamic acid but not recombinant factor VIIa attenuate tissue plasminogen activator-induced hyperfibrinolysis in human whole blood.

Dirkmann D, Görlinger K, Gisbertz C, Dusse F, Peters J.

Anesth Analg. 2012 Jun;114(6):1182-8. doi: 10.1213/ANE.0b013e31823b6683. Epub 2011 Nov 21.

PMID:
22104068
13.

Tranexamic acid: a review of its use in the treatment of hyperfibrinolysis.

McCormack PL.

Drugs. 2012 Mar 26;72(5):585-617. doi: 10.2165/11209070-000000000-00000. Review.

PMID:
22397329
14.

Clot lysis time in platelet-rich plasma: method assessment, comparison with assays in platelet-free and platelet-poor plasmas, and response to tranexamic acid.

Panes O, Padilla O, Matus V, Sáez CG, Berkovits A, Pereira J, Mezzano D.

Platelets. 2012;23(1):36-44. doi: 10.3109/09537104.2011.596957. Epub 2011 Jul 25.

PMID:
21787173
15.

The effective concentration of tranexamic acid for inhibition of fibrinolysis in neonatal plasma in vitro.

Yee BE, Wissler RN, Zanghi CN, Feng C, Eaton MP.

Anesth Analg. 2013 Oct;117(4):767-72. doi: 10.1213/ANE.0b013e3182a22258. Epub 2013 Sep 10.

PMID:
24023015
16.

Plasminogen-plasmin system IX. Specific binding of tranexamic acid to plasmin.

Iwamoto M.

Thromb Diath Haemorrh. 1975 Jun 30;33(3):573-85.

PMID:
125463
17.

The effect of long-term, low-dose tranexamic acid treatment on platelet dysfunction and haemoglobin levels in haemodialysis patients.

Sabovic M, Zupan IP, Salobir B, Zupan I, Cernelc P, Lavre J, Vujkovac B.

Thromb Haemost. 2005 Dec;94(6):1245-50.

PMID:
16411401
18.

Clinical application of inhibitors of fibrinolysis.

Verstraete M.

Drugs. 1985 Mar;29(3):236-61. Review.

PMID:
2580684
19.

Does tranexamic acid reduce desmopressin-induced hyperfibrinolysis?

Ozal E, Kuralay E, Bingöl H, Cingöz F, Ceylan S, Tatar H.

J Thorac Cardiovasc Surg. 2002 Mar;123(3):539-43.

PMID:
11882828
20.

The inhibiting effect of factor XIII on hyperfibrinolysis.

Theusinger OM.

Anesth Analg. 2012 Jun;114(6):1149-50. doi: 10.1213/ANE.0b013e318252e9f1. No abstract available.

PMID:
22615440
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