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Results: 1 to 20 of 99

1.

Hypoxia antagonizes glucose deprivation on interleukin 6 expression in an Akt dependent, but HIF-1/2α independent manner.

Choi SJ, Shin IJ, Je KH, Min EK, Kim EJ, Kim HS, Choe S, Kim DE, Lee DK.

PLoS One. 2013;8(3):e58662. doi: 10.1371/journal.pone.0058662. Epub 2013 Mar 8.

PMID:
23520526
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Hypoxia-induced iNOS expression in microglia is regulated by the PI3-kinase/Akt/mTOR signaling pathway and activation of hypoxia inducible factor-1alpha.

Lu DY, Liou HC, Tang CH, Fu WM.

Biochem Pharmacol. 2006 Oct 16;72(8):992-1000. Epub 2006 Aug 17.

PMID:
16919605
[PubMed - indexed for MEDLINE]
4.

[Hypoxia induced HIF-1 accumulation and VEGF expression in gastric epithelial mucosa cell: involvement of ERK1/2 and PI3K/Akt].

Liu L, Ning X, Han S, Zhang H, Sun L, Shi Y, Sun S, Guo C, Yin F, Qiao T, Wu K, Fan D.

Mol Biol (Mosk). 2008 May-Jun;42(3):459-69. Russian.

PMID:
18702304
[PubMed - indexed for MEDLINE]
5.

Chronic hypoxia leads to a glycolytic phenotype and suppressed HIF-2 signaling in PC12 cells.

Zhdanov AV, Dmitriev RI, Golubeva AV, Gavrilova SA, Papkovsky DB.

Biochim Biophys Acta. 2013 Jun;1830(6):3553-69. doi: 10.1016/j.bbagen.2013.02.016. Epub 2013 Feb 24.

PMID:
23462283
[PubMed - indexed for MEDLINE]
Free Article
6.

Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha.

Park SK, Dadak AM, Haase VH, Fontana L, Giaccia AJ, Johnson RS.

Mol Cell Biol. 2003 Jul;23(14):4959-71.

PMID:
12832481
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Glucose utilization is essential for hypoxia-inducible factor 1 alpha-dependent phosphorylation of c-Jun.

Laderoute KR, Calaoagan JM, Knapp M, Johnson RS.

Mol Cell Biol. 2004 May;24(10):4128-37.

PMID:
15121835
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages.

Basak C, Pathak SK, Bhattacharyya A, Mandal D, Pathak S, Kundu M.

J Biol Chem. 2005 Feb 11;280(6):4279-88. Epub 2004 Nov 23.

PMID:
15561713
[PubMed - indexed for MEDLINE]
Free Article
9.

Increased activation of the hypoxia-inducible factor pathway in varicose veins.

Lim CS, Kiriakidis S, Paleolog EM, Davies AH.

J Vasc Surg. 2012 May;55(5):1427-39. doi: 10.1016/j.jvs.2011.10.111. Epub 2012 Jan 24.

PMID:
22277691
[PubMed - indexed for MEDLINE]
Free Article
10.

PI3K/Akt contributes to increased expression of Toll-like receptor 4 in macrophages exposed to hypoxic stress.

Kim SY, Jeong E, Joung SM, Lee JY.

Biochem Biophys Res Commun. 2012 Mar 16;419(3):466-71. doi: 10.1016/j.bbrc.2012.02.015.

PMID:
22424098
[PubMed - indexed for MEDLINE]
11.

Effect of arachidonic acid on hypoxia-induced IL-6 production in mouse ES cells: Involvement of MAPKs, NF-kappaB, and HIF-1alpha.

Lee SH, Lee YJ, Han HJ.

J Cell Physiol. 2010 Mar;222(3):574-85. doi: 10.1002/jcp.21973.

PMID:
19950212
[PubMed - indexed for MEDLINE]
12.

Effects of hypoxia on transcription factor expression in human monocytes and macrophages.

Elbarghati L, Murdoch C, Lewis CE.

Immunobiology. 2008;213(9-10):899-908. doi: 10.1016/j.imbio.2008.07.016. Epub 2008 Aug 30.

PMID:
18926304
[PubMed - indexed for MEDLINE]
13.

Baicalein suppresses hypoxia-induced HIF-1alpha protein accumulation and activation through inhibition of reactive oxygen species and PI 3-kinase/Akt pathway in BV2 murine microglial cells.

Hwang KY, Oh YT, Yoon H, Lee J, Kim H, Choe W, Kang I.

Neurosci Lett. 2008 Oct 31;444(3):264-9. doi: 10.1016/j.neulet.2008.08.057. Epub 2008 Aug 27.

PMID:
18771709
[PubMed - indexed for MEDLINE]
14.
15.

Kaempferol acts through mitogen-activated protein kinases and protein kinase B/AKT to elicit protection in a model of neuroinflammation in BV2 microglial cells.

Park SE, Sapkota K, Kim S, Kim H, Kim SJ.

Br J Pharmacol. 2011 Oct;164(3):1008-25. doi: 10.1111/j.1476-5381.2011.01389.x.

PMID:
21449918
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The Akt/mTOR pathway assures the synthesis of HIF-1alpha protein in a glucose- and reoxygenation-dependent manner in irradiated tumors.

Harada H, Itasaka S, Kizaka-Kondoh S, Shibuya K, Morinibu A, Shinomiya K, Hiraoka M.

J Biol Chem. 2009 Feb 20;284(8):5332-42. doi: 10.1074/jbc.M806653200. Epub 2008 Dec 19.

PMID:
19098000
[PubMed - indexed for MEDLINE]
Free Article
17.

Diosgenin induces hypoxia-inducible factor-1 activation and angiogenesis through estrogen receptor-related phosphatidylinositol 3-kinase/Akt and p38 mitogen-activated protein kinase pathways in osteoblasts.

Yen ML, Su JL, Chien CL, Tseng KW, Yang CY, Chen WF, Chang CC, Kuo ML.

Mol Pharmacol. 2005 Oct;68(4):1061-73. Epub 2005 Jul 5.

PMID:
15998873
[PubMed - indexed for MEDLINE]
Free Article
18.

Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells.

Merighi S, Benini A, Mirandola P, Gessi S, Varani K, Simioni C, Leung E, Maclennan S, Baraldi PG, Borea PA.

Mol Pharmacol. 2007 Aug;72(2):395-406. Epub 2007 May 8.

PMID:
17488804
[PubMed - indexed for MEDLINE]
Free Article
19.

Hypoxia-inducible factor-1α regulates the expression of genes in hypoxic hepatic stellate cells important for collagen deposition and angiogenesis.

Copple BL, Bai S, Burgoon LD, Moon JO.

Liver Int. 2011 Feb;31(2):230-44. doi: 10.1111/j.1478-3231.2010.02347.x. Epub 2010 Sep 29.

PMID:
20880076
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Peptidoglycan induces interleukin-6 expression through the TLR2 receptor, JNK, c-Jun, and AP-1 pathways in microglia.

Lin HY, Tang CH, Chen JH, Chuang JY, Huang SM, Tan TW, Lai CH, Lu DY.

J Cell Physiol. 2011 Jun;226(6):1573-82. doi: 10.1002/jcp.22489.

PMID:
20945380
[PubMed - indexed for MEDLINE]

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