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Results: 1 to 20 of 107

1.

IRAK4 turns IL-10+ phospho-FOXO+ monocytes into pro-inflammatory cells by suppression of protein kinase B.

Over B, Ziegler S, Foermer S, Weber AN, Bode KA, Heeg K, Bekeredjian-Ding I.

Eur J Immunol. 2013 Jun;43(6):1630-42. doi: 10.1002/eji.201243217. Epub 2013 Apr 30.

PMID:
23519847
[PubMed - indexed for MEDLINE]
3.

Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells.

Li X, Tupper JC, Bannerman DD, Winn RK, Rhodes CJ, Harlan JM.

Infect Immun. 2003 Aug;71(8):4414-20.

PMID:
12874320
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound.

Loiarro M, Capolunghi F, Fantò N, Gallo G, Campo S, Arseni B, Carsetti R, Carminati P, De Santis R, Ruggiero V, Sette C.

J Leukoc Biol. 2007 Oct;82(4):801-10. Epub 2007 Jun 4.

PMID:
17548806
[PubMed - indexed for MEDLINE]
Free Article
5.

Complete dependence on IRAK4 kinase activity in TLR2, but not TLR4, signaling pathways underlies decreased cytokine production and increased susceptibility to Streptococcus pneumoniae infection in IRAK4 kinase-inactive mice.

Pennini ME, Perkins DJ, Salazar AM, Lipsky M, Vogel SN.

J Immunol. 2013 Jan 1;190(1):307-16. doi: 10.4049/jimmunol.1201644. Epub 2012 Dec 3.

PMID:
23209321
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Dual regulation of osteopontin production by TLR stimulation in dendritic cells.

Salvi V, Scutera S, Rossi S, Zucca M, Alessandria M, Greco D, Bosisio D, Sozzani S, Musso T.

J Leukoc Biol. 2013 Jul;94(1):147-58. doi: 10.1189/jlb.0412194. Epub 2013 Apr 22.

PMID:
23610145
[PubMed - indexed for MEDLINE]
Free Article
7.

Interleukin 1/Toll-like receptor-induced autophosphorylation activates interleukin 1 receptor-associated kinase 4 and controls cytokine induction in a cell type-specific manner.

Cushing L, Stochaj W, Siegel M, Czerwinski R, Dower K, Wright Q, Hirschfield M, Casanova JL, Picard C, Puel A, Lin LL, Rao VR.

J Biol Chem. 2014 Apr 11;289(15):10865-75. doi: 10.1074/jbc.M113.544809. Epub 2014 Feb 24.

PMID:
24567333
[PubMed - indexed for MEDLINE]
8.
9.

Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by miR-132 and miR-212.

Nahid MA, Yao B, Dominguez-Gutierrez PR, Kesavalu L, Satoh M, Chan EK.

J Immunol. 2013 Feb 1;190(3):1250-63. doi: 10.4049/jimmunol.1103060. Epub 2012 Dec 21.

PMID:
23264652
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.

Piao W, Song C, Chen H, Diaz MA, Wahl LM, Fitzgerald KA, Li L, Medvedev AE.

J Leukoc Biol. 2009 Oct;86(4):863-75. doi: 10.1189/jlb.0309189. Epub 2009 Aug 5.

PMID:
19656901
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Morphine inhibits murine dendritic cell IL-23 production by modulating Toll-like receptor 2 and Nod2 signaling.

Wang J, Ma J, Charboneau R, Barke R, Roy S.

J Biol Chem. 2011 Mar 25;286(12):10225-32. doi: 10.1074/jbc.M110.188680. Epub 2011 Jan 18.

PMID:
21245149
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components.

Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, Ren T, Cody MJ, Michalek SM, Rice NR, Vogel SN.

J Immunol. 2003 Jan 1;170(1):508-19.

PMID:
12496438
[PubMed - indexed for MEDLINE]
Free Article
13.

Oncogenically active MYD88 mutations in human lymphoma.

Ngo VN, Young RM, Schmitz R, Jhavar S, Xiao W, Lim KH, Kohlhammer H, Xu W, Yang Y, Zhao H, Shaffer AL, Romesser P, Wright G, Powell J, Rosenwald A, Muller-Hermelink HK, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Fisher RI, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Staudt LM.

Nature. 2011 Feb 3;470(7332):115-9. doi: 10.1038/nature09671. Epub 2010 Dec 22.

PMID:
21179087
[PubMed - indexed for MEDLINE]
14.

Role of IRAK4 and IRF3 in the control of intracellular infection with Chlamydia pneumoniae.

Trumstedt C, Eriksson E, Lundberg AM, Yang TB, Yan ZQ, Wigzell H, Rottenberg ME.

J Leukoc Biol. 2007 Jun;81(6):1591-8. Epub 2007 Mar 14.

PMID:
17360955
[PubMed - indexed for MEDLINE]
Free Article
15.

Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide.

Martin M, Schifferle RE, Cuesta N, Vogel SN, Katz J, Michalek SM.

J Immunol. 2003 Jul 15;171(2):717-25.

PMID:
12847238
[PubMed - indexed for MEDLINE]
Free Article
16.

Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP.

Andreakos E, Sacre SM, Smith C, Lundberg A, Kiriakidis S, Stonehouse T, Monaco C, Feldmann M, Foxwell BM.

Blood. 2004 Mar 15;103(6):2229-37. Epub 2003 Nov 20.

PMID:
14630816
[PubMed - indexed for MEDLINE]
Free Article
17.
18.

Activation of MyD88 signaling upon staphylococcal enterotoxin binding to MHC class II molecules.

Kissner TL, Ruthel G, Alam S, Ulrich RG, Fernandez S, Saikh KU.

PLoS One. 2011 Jan 20;6(1):e15985. doi: 10.1371/journal.pone.0015985.

PMID:
21283748
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Interleukin-32α production is regulated by MyD88-dependent and independent pathways in IL-1β-stimulated human alveolar epithelial cells.

Ko NY, Mun SH, Lee SH, Kim JW, Kim do K, Kim HS, Her E, Kim SH, Won HS, Shin HS, Kim HS, Kim YM, Choi WS.

Immunobiology. 2011 Jan-Feb;216(1-2):32-40. doi: 10.1016/j.imbio.2010.03.007. Epub 2010 Mar 19.

PMID:
20430472
[PubMed - indexed for MEDLINE]
20.

PKC-alpha controls MYD88-dependent TLR/IL-1R signaling and cytokine production in mouse and human dendritic cells.

Langlet C, Springael C, Johnson J, Thomas S, Flamand V, Leitges M, Goldman M, Aksoy E, Willems F.

Eur J Immunol. 2010 Feb;40(2):505-15. doi: 10.1002/eji.200939391.

PMID:
19950169
[PubMed - indexed for MEDLINE]

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