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Results: 1 to 20 of 104

1.

The histone demethylase PHF8 governs retinoic acid response in acute promyelocytic leukemia.

Arteaga MF, Mikesch JH, Qiu J, Christensen J, Helin K, Kogan SC, Dong S, So CW.

Cancer Cell. 2013 Mar 18;23(3):376-89. doi: 10.1016/j.ccr.2013.02.014.

PMID:
23518351
[PubMed - indexed for MEDLINE]
Free Article
2.

Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia.

Guidez F, Ivins S, Zhu J, Söderström M, Waxman S, Zelent A.

Blood. 1998 Apr 15;91(8):2634-42.

PMID:
9531570
[PubMed - indexed for MEDLINE]
Free Article
3.
4.

Targeting of PML/RARalpha is lethal to retinoic acid-resistant promyelocytic leukemia cells.

Nason-Burchenal K, Allopenna J, Bègue A, Stéhelin D, Dmitrovsky E, Martin P.

Blood. 1998 Sep 1;92(5):1758-67.

PMID:
9716606
[PubMed - indexed for MEDLINE]
Free Article
5.

Mutations in the E-domain of RAR portion of the PML/RAR chimeric gene may confer clinical resistance to all-trans retinoic acid in acute promyelocytic leukemia.

Imaizumi M, Suzuki H, Yoshinari M, Sato A, Saito T, Sugawara A, Tsuchiya S, Hatae Y, Fujimoto T, Kakizuka A, Konno T, Iinuma K.

Blood. 1998 Jul 15;92(2):374-82.

PMID:
9657734
[PubMed - indexed for MEDLINE]
Free Article
6.

PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL.

Tabe Y, Konopleva M, Kondo Y, Contractor R, Tsao T, Konoplev S, Shi Y, Ling X, Watt JC, Tsutsumi-Ishii Y, Ohsaka A, Nagaoka I, Issa JP, Kogan SC, Andreeff M.

Cancer Biol Ther. 2007 Dec;6(12):1967-77. Epub 2007 Sep 4.

PMID:
18075297
[PubMed - indexed for MEDLINE]
Free Article
7.

Tyrosine kinase inhibitor STI571 potentiates the pharmacologic activity of retinoic acid in acute promyelocytic leukemia cells: effects on the degradation of RARalpha and PML-RARalpha.

Gianni' M, Kalaç Y, Ponzanelli I, Rambaldi A, Terao M, Garattini E.

Blood. 2001 May 15;97(10):3234-43.

PMID:
11342454
[PubMed - indexed for MEDLINE]
Free Article
8.

Accelerated degradation of PML-retinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: possible role of the proteasome pathway.

Yoshida H, Kitamura K, Tanaka K, Omura S, Miyazaki T, Hachiya T, Ohno R, Naoe T.

Cancer Res. 1996 Jul 1;56(13):2945-8.

PMID:
8674046
[PubMed - indexed for MEDLINE]
Free Article
9.

Response to histone deacetylase inhibition of novel PML/RARalpha mutants detected in retinoic acid-resistant APL cells.

Côté S, Rosenauer A, Bianchini A, Seiter K, Vandewiele J, Nervi C, Miller WH Jr.

Blood. 2002 Oct 1;100(7):2586-96.

PMID:
12239173
[PubMed - indexed for MEDLINE]
Free Article
10.

Transcription therapy for acute promyelocytic leukaemia.

Douer D.

Expert Opin Investig Drugs. 2000 Feb;9(2):329-46. Review.

PMID:
11060680
[PubMed - indexed for MEDLINE]
11.

Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization.

Nason-Burchenal K, Maerz W, Albanell J, Allopenna J, Martin P, Moore MA, Dmitrovsky E.

Differentiation. 1997 Aug;61(5):321-31.

PMID:
9342843
[PubMed - indexed for MEDLINE]
12.

The cleavage product deltaPML-RARalpha contributes to all-trans retinoic acid-mediated differentiation in acute promyelocytic leukemia cells.

Jing Y, Xia L, Lu M, Waxman S.

Oncogene. 2003 Jun 26;22(26):4083-91.

PMID:
12821942
[PubMed - indexed for MEDLINE]
13.

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.

Schenk T, Chen WC, Göllner S, Howell L, Jin L, Hebestreit K, Klein HU, Popescu AC, Burnett A, Mills K, Casero RA Jr, Marton L, Woster P, Minden MD, Dugas M, Wang JC, Dick JE, Müller-Tidow C, Petrie K, Zelent A.

Nat Med. 2012 Mar 11;18(4):605-11. doi: 10.1038/nm.2661.

PMID:
22406747
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The PML-RARalpha fusion protein and targeted therapy for acute promyelocytic leukemia.

Jing Y.

Leuk Lymphoma. 2004 Apr;45(4):639-48. Review.

PMID:
15160934
[PubMed - indexed for MEDLINE]
15.
16.

Granulocytic differentiation of human NB4 promyelocytic leukemia cells induced by all-trans retinoic acid metabolites.

Idres N, Benoît G, Flexor MA, Lanotte M, Chabot GG.

Cancer Res. 2001 Jan 15;61(2):700-5.

PMID:
11212271
[PubMed - indexed for MEDLINE]
Free Article
17.

Differential gene expression in retinoic acid-induced differentiation of acute promyelocytic leukemia cells, NB4 and HL-60 cells.

Lee KH, Chang MY, Ahn JI, Yu DH, Jung SS, Choi JH, Noh YH, Lee YS, Ahn MJ.

Biochem Biophys Res Commun. 2002 Sep 6;296(5):1125-33.

PMID:
12207890
[PubMed - indexed for MEDLINE]
18.

The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation.

Qiu J, Shi G, Jia Y, Li J, Wu M, Li J, Dong S, Wong J.

Cell Res. 2010 Aug;20(8):908-18. doi: 10.1038/cr.2010.81. Epub 2010 Jun 15.

PMID:
20548336
[PubMed - indexed for MEDLINE]
19.

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia.

Grignani F, De Matteis S, Nervi C, Tomassoni L, Gelmetti V, Cioce M, Fanelli M, Ruthardt M, Ferrara FF, Zamir I, Seiser C, Grignani F, Lazar MA, Minucci S, Pelicci PG.

Nature. 1998 Feb 19;391(6669):815-8.

PMID:
9486655
[PubMed - indexed for MEDLINE]

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