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Items: 1 to 20 of 107


Mcph1-deficient mice reveal a role for MCPH1 in otitis media.

Chen J, Ingham N, Clare S, Raisen C, Vancollie VE, Ismail O, McIntyre RE, Tsang SH, Mahajan VB, Dougan G, Adams DJ, White JK, Steel KP.

PLoS One. 2013;8(3):e58156. doi: 10.1371/journal.pone.0058156. Epub 2013 Mar 13.


Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.

Tateossian H, Morse S, Parker A, Mburu P, Warr N, Acevedo-Arozena A, Cheeseman M, Wells S, Brown SD.

Hum Mol Genet. 2013 Jul 1;22(13):2553-65. doi: 10.1093/hmg/ddt103. Epub 2013 Mar 3.


Otitis media in a new mouse model for CHARGE syndrome with a deletion in the Chd7 gene.

Tian C, Yu H, Yang B, Han F, Zheng Y, Bartels CF, Schelling D, Arnold JE, Scacheri PC, Zheng QY.

PLoS One. 2012;7(4):e34944. doi: 10.1371/journal.pone.0034944. Epub 2012 Apr 23.


Targeting of Slc25a21 is associated with orofacial defects and otitis media due to disrupted expression of a neighbouring gene.

Maguire S, Estabel J, Ingham N, Pearson S, Ryder E, Carragher DM, Walker N; Sanger MGP Slc25a21 Project Team, Bussell J, Chan WI, Keane TM, Adams DJ, Scudamore CL, Lelliott CJ, Ramírez-Solis R, Karp NA, Steel KP, White JK, Gerdin AK.

PLoS One. 2014 Mar 18;9(3):e91807. doi: 10.1371/journal.pone.0091807. eCollection 2014.


Sh3pxd2b mice are a model for craniofacial dysmorphology and otitis media.

Yang B, Tian C, Zhang ZG, Han FC, Azem R, Yu H, Zheng Y, Jin G, Arnold JE, Zheng QY.

PLoS One. 2011;6(7):e22622. doi: 10.1371/journal.pone.0022622. Epub 2011 Jul 27.


Exome sequencing identifies a missense mutation in Isl1 associated with low penetrance otitis media in dearisch mice.

Hilton JM, Lewis MA, Grati M, Ingham N, Pearson S, Laskowski RA, Adams DJ, Steel KP.

Genome Biol. 2011 Sep 21;12(9):R90. doi: 10.1186/gb-2011-12-9-r90.


Eya4-deficient mice are a model for heritable otitis media.

Depreux FF, Darrow K, Conner DA, Eavey RD, Liberman MC, Seidman CE, Seidman JG.

J Clin Invest. 2008 Feb;118(2):651-8. doi: 10.1172/JCI32899.


Ectopic mineralization in the middle ear and chronic otitis media with effusion caused by RPL38 deficiency in the Tail-short (Ts) mouse.

Noben-Trauth K, Latoche JR.

J Biol Chem. 2011 Jan 28;286(4):3079-93. doi: 10.1074/jbc.M110.184598. Epub 2010 Nov 9.


C3H/HeJ mouse model for spontaneous chronic otitis media.

MacArthur CJ, Hefeneider SH, Kempton JB, Trune DR.

Laryngoscope. 2006 Jul;116(7):1071-9. Erratum in: Laryngoscope. 2006 Nov;116(11):2098.


DNA damage response in microcephaly development of MCPH1 mouse model.

Zhou ZW, Tapias A, Bruhn C, Gruber R, Sukchev M, Wang ZQ.

DNA Repair (Amst). 2013 Aug;12(8):645-55. doi: 10.1016/j.dnarep.2013.04.017. Epub 2013 May 15.


Mcph1/Brit1 deficiency promotes genomic instability and tumor formation in a mouse model.

Liang Y, Gao H, Lin SY, Goss JA, Du C, Li K.

Oncogene. 2015 Aug 13;34(33):4368-78. doi: 10.1038/onc.2014.367. Epub 2014 Nov 3.


Hearing loss in a mouse model of 22q11.2 Deletion Syndrome.

Fuchs JC, Zinnamon FA, Taylor RR, Ivins S, Scambler PJ, Forge A, Tucker AS, Linden JF.

PLoS One. 2013 Nov 14;8(11):e80104. doi: 10.1371/journal.pone.0080104. eCollection 2013.


Mouse models of induced otitis media.

Ryan AF, Ebmeyer J, Furukawa M, Pak K, Melhus A, Wasserman SI, Chung WH.

Brain Res. 2006 May 26;1091(1):3-8. Epub 2006 Jun 9. Review.


Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function.

Trimborn M, Ghani M, Walther DJ, Dopatka M, Dutrannoy V, Busche A, Meyer F, Nowak S, Nowak J, Zabel C, Klose J, Esquitino V, Garshasbi M, Kuss AW, Ropers HH, Mueller S, Poehlmann C, Gavvovidis I, Schindler D, Sperling K, Neitzel H.

PLoS One. 2010 Feb 16;5(2):e9242. doi: 10.1371/journal.pone.0009242.


Spontaneous development of otitis media in plasminogen-deficient mice.

Eriksson PO, Li J, Ny T, Hellström S.

Int J Med Microbiol. 2006 Nov;296(7):501-9. Epub 2006 Sep 7.


Mutation in Phex gene predisposes BALB/c-Phex(Hyp-Duk)/Y mice to otitis media.

Han F, Yu H, Li P, Zhang J, Tian C, Li H, Zheng QY.

PLoS One. 2012;7(9):e43010. doi: 10.1371/journal.pone.0043010. Epub 2012 Sep 28.


Oto-endoscopy: a reliable and validated technique for phenotyping otitis media in the mouse.

Bhutta MF, Hedge EA, Parker A, Cheeseman MT, Brown SD.

Hear Res. 2011 Feb;272(1-2):5-12. doi: 10.1016/j.heares.2010.09.002. Epub 2010 Sep 24.


Inner ear tissue remodeling and ion homeostasis gene alteration in murine chronic otitis media.

MacArthur CJ, Hausman F, Kempton JB, Sautter N, Trune DR.

Otol Neurotol. 2013 Feb;34(2):338-46. doi: 10.1097/MAO.0b013e31827b4d0a.


Evaluation of the mouse model for acute otitis media.

MacArthur CJ, Hefeneider SH, Kempton JB, Parrish SK, McCoy SL, Trune DR.

Hear Res. 2006 Sep;219(1-2):12-23. Epub 2006 Aug 2.


[Morphological and functional alterations of ear in lysosomal neuraminidase gene deficient mouse].

Guo YK, Xie DH, Yang XM.

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2005 Nov;40(11):824-9. Chinese.

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