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Results: 1 to 20 of 136

1.

Phosphodiesterase inhibition rescues chronic cognitive deficits induced by traumatic brain injury.

Titus DJ, Sakurai A, Kang Y, Furones C, Jergova S, Santos R, Sick TJ, Atkins CM.

J Neurosci. 2013 Mar 20;33(12):5216-26. doi: 10.1523/JNEUROSCI.5133-12.2013.

PMID:
23516287
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Modulation of the cAMP signaling pathway after traumatic brain injury.

Atkins CM, Oliva AA Jr, Alonso OF, Pearse DD, Bramlett HM, Dietrich WD.

Exp Neurol. 2007 Nov;208(1):145-58. Epub 2007 Aug 29.

PMID:
17916353
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Age-dependent alterations in cAMP signaling contribute to synaptic plasticity deficits following traumatic brain injury.

Titus DJ, Furones C, Kang Y, Atkins CM.

Neuroscience. 2013 Feb 12;231:182-94. doi: 10.1016/j.neuroscience.2012.12.002. Epub 2012 Dec 10.

PMID:
23238576
[PubMed - indexed for MEDLINE]
Free PMC Article
4.
5.

Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling.

Li YF, Cheng YF, Huang Y, Conti M, Wilson SP, O'Donnell JM, Zhang HT.

J Neurosci. 2011 Jan 5;31(1):172-83. doi: 10.1523/JNEUROSCI.5236-10.2011.

PMID:
21209202
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Deficits in ERK and CREB activation in the hippocampus after traumatic brain injury.

Atkins CM, Falo MC, Alonso OF, Bramlett HM, Dietrich WD.

Neurosci Lett. 2009 Aug 7;459(2):52-6. doi: 10.1016/j.neulet.2009.04.064. Epub 2009 May 3.

PMID:
19416748
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Rescue of cAMP response element-binding protein signaling reversed spatial memory retention impairments induced by subanesthetic dose of propofol.

Zhang H, Zhang SB, Zhang QQ, Liu M, He XY, Zou Z, Sun HJ, You ZD, Shi XY.

CNS Neurosci Ther. 2013 Jul;19(7):484-93. doi: 10.1111/cns.12088. Epub 2013 Mar 28.

PMID:
23534694
[PubMed - indexed for MEDLINE]
8.

Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25-35 or Aβ1-40 peptide in rats.

Cheng YF, Wang C, Lin HB, Li YF, Huang Y, Xu JP, Zhang HT.

Psychopharmacology (Berl). 2010 Oct;212(2):181-91. doi: 10.1007/s00213-010-1943-3. Epub 2010 Jul 17.

PMID:
20640406
[PubMed - indexed for MEDLINE]
9.

Pre-Injury magnesium treatment prevents traumatic brain injury-induced hippocampal ERK activation, neuronal loss, and cognitive dysfunction in the radial-arm maze test.

Enomoto T, Osugi T, Satoh H, McIntosh TK, Nabeshima T.

J Neurotrauma. 2005 Jul;22(7):783-92.

PMID:
16004581
[PubMed - indexed for MEDLINE]
10.

Prevention of cerebral ischemia-induced memory deficits by inhibition of phosphodiesterase-4 in rats.

Li LX, Cheng YF, Lin HB, Wang C, Xu JP, Zhang HT.

Metab Brain Dis. 2011 Mar;26(1):37-47. doi: 10.1007/s11011-011-9235-0. Epub 2011 Feb 17.

PMID:
21327879
[PubMed - indexed for MEDLINE]
11.

The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats.

Wang C, Yang XM, Zhuo YY, Zhou H, Lin HB, Cheng YF, Xu JP, Zhang HT.

Int J Neuropsychopharmacol. 2012 Jul;15(6):749-66. doi: 10.1017/S1461145711000836. Epub 2011 Jun 9.

PMID:
21733236
[PubMed - indexed for MEDLINE]
12.

Effects of protein kinase A and G inhibitors on hippocampal cholinergic markers expressions in rolipram- and sildenafil-induced spatial memory improvement.

Hosseini-Sharifabad A, Ghahremani MH, Sabzevari O, Naghdi N, Abdollahi M, Beyer C, Bollen E, Prickaerts J, Roghani A, Sharifzadeh M.

Pharmacol Biochem Behav. 2012 May;101(3):311-9. doi: 10.1016/j.pbb.2012.01.017. Epub 2012 Jan 28.

PMID:
22306745
[PubMed - indexed for MEDLINE]
13.

Lithium reduces BACE1 overexpression, β amyloid accumulation, and spatial learning deficits in mice with traumatic brain injury.

Yu F, Zhang Y, Chuang DM.

J Neurotrauma. 2012 Sep;29(13):2342-51. doi: 10.1089/neu.2012.2449. Epub 2012 Jul 2.

PMID:
22583494
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus.

Zhang HT, Zhao Y, Huang Y, Dorairaj NR, Chandler LJ, O'Donnell JM.

Neuropsychopharmacology. 2004 Aug;29(8):1432-9.

PMID:
15114341
[PubMed - indexed for MEDLINE]
Free Article
15.

Blocking leukotriene synthesis attenuates the pathophysiology of traumatic brain injury and associated cognitive deficits.

Corser-Jensen CE, Goodell DJ, Freund RK, Serbedzija P, Murphy RC, Farias SE, Dell'Acqua ML, Frey LC, Serkova N, Heidenreich KA.

Exp Neurol. 2014 Jun;256:7-16. doi: 10.1016/j.expneurol.2014.03.008. Epub 2014 Mar 25.

PMID:
24681156
[PubMed - indexed for MEDLINE]
16.
17.

Enhanced hippocampal neurogenesis by intraventricular S100B infusion is associated with improved cognitive recovery after traumatic brain injury.

Kleindienst A, McGinn MJ, Harvey HB, Colello RJ, Hamm RJ, Bullock MR.

J Neurotrauma. 2005 Jun;22(6):645-55.

PMID:
15941374
[PubMed - indexed for MEDLINE]
18.

Postinjury administration of L-deprenyl improves cognitive function and enhances neuroplasticity after traumatic brain injury.

Zhu J, Hamm RJ, Reeves TM, Povlishock JT, Phillips LL.

Exp Neurol. 2000 Nov;166(1):136-52.

PMID:
11031090
[PubMed - indexed for MEDLINE]
19.

Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Galphas, a G-protein subunit genetically linked to schizophrenia.

Kelly MP, Stein JM, Vecsey CG, Favilla C, Yang X, Bizily SF, Esposito MF, Wand G, Kanes SJ, Abel T.

Mol Psychiatry. 2009 Apr;14(4):398-415, 347. doi: 10.1038/mp.2008.124. Epub 2008 Nov 25. Erratum in: Mol Psychiatry. 2009 Dec;14(12):1145.

PMID:
19030002
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

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