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Results: 1 to 20 of 73

1.

Development of novel bioanalytical methods to determine the effective concentrations of phosphorodiamidate morpholino oligomers in tissues and cells.

Schnell FJ, Crumley SL, Mourich DV, Iversen PL.

Biores Open Access. 2013 Feb;2(1):61-6. doi: 10.1089/biores.2012.0276.

PMID:
23515175
[PubMed]
Free PMC Article
2.

Intracellular delivery strategies for antisense phosphorodiamidate morpholino oligomers.

Ghosh C, Iversen PL.

Antisense Nucleic Acid Drug Dev. 2000 Aug;10(4):263-74.

PMID:
10984120
[PubMed - indexed for MEDLINE]
3.

Inhibition of infectious haematopoietic necrosis virus in cell cultures with peptide-conjugated morpholino oligomers.

Alonso M, Stein DA, Thomann E, Moulton HM, Leong JC, Iversen P, Mourich DV.

J Fish Dis. 2005 Jul;28(7):399-410.

PMID:
16083445
[PubMed - indexed for MEDLINE]
4.

Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers.

Stein DA, Skilling DE, Iversen PL, Smith AW.

Antisense Nucleic Acid Drug Dev. 2001 Oct;11(5):317-25.

PMID:
11763348
[PubMed - indexed for MEDLINE]
5.

Cellular uptake of neutral phosphorodiamidate morpholino oligomers.

Iversen PL, Aird KM, Wu R, Morse MM, Devi GR.

Curr Pharm Biotechnol. 2009 Sep;10(6):579-88. Epub 2009 Sep 1.

PMID:
19619124
[PubMed - indexed for MEDLINE]
6.

Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers.

Ge Q, Pastey M, Kobasa D, Puthavathana P, Lupfer C, Bestwick RK, Iversen PL, Chen J, Stein DA.

Antimicrob Agents Chemother. 2006 Nov;50(11):3724-33. Epub 2006 Sep 11.

PMID:
16966399
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Antisense phosphorodiamidate morpholino oligomer inhibits viability of Escherichia coli in pure culture and in mouse peritonitis.

Geller BL, Deere J, Tilley L, Iversen PL.

J Antimicrob Chemother. 2005 Jun;55(6):983-8. Epub 2005 May 4.

PMID:
15872045
[PubMed - indexed for MEDLINE]
Free Article
8.

Androgen receptor down-regulation in prostate cancer with phosphorodiamidate morpholino antisense oligomers.

Ko YJ, Devi GR, London CA, Kayas A, Reddy MT, Iversen PL, Bubley GJ, Balk SP.

J Urol. 2004 Sep;172(3):1140-4.

PMID:
15311058
[PubMed - indexed for MEDLINE]
9.

HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers.

Moulton HM, Hase MC, Smith KM, Iversen PL.

Antisense Nucleic Acid Drug Dev. 2003 Feb;13(1):31-43.

PMID:
12691534
[PubMed - indexed for MEDLINE]
10.

Antisense peptide-phosphorodiamidate morpholino oligomer conjugate: dose-response in mice infected with Escherichia coli.

Tilley LD, Mellbye BL, Puckett SE, Iversen PL, Geller BL.

J Antimicrob Chemother. 2007 Jan;59(1):66-73. Epub 2006 Oct 31.

PMID:
17079242
[PubMed - indexed for MEDLINE]
Free Article
11.

Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides.

Moulton HM, Nelson MH, Hatlevig SA, Reddy MT, Iversen PL.

Bioconjug Chem. 2004 Mar-Apr;15(2):290-9.

PMID:
15025524
[PubMed - indexed for MEDLINE]
12.

Delivery of phosphorodiamidate morpholino antisense oligomers in cancer cells.

Devi GR.

Methods Mol Biol. 2009;542:351-61. doi: 10.1007/978-1-59745-561-9_19.

PMID:
19565912
[PubMed - indexed for MEDLINE]
13.

Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity.

Nelson MH, Stein DA, Kroeker AD, Hatlevig SA, Iversen PL, Moulton HM.

Bioconjug Chem. 2005 Jul-Aug;16(4):959-66.

PMID:
16029037
[PubMed - indexed for MEDLINE]
14.

Neutrally charged phosphorodiamidate morpholino antisense oligomers: uptake, efficacy and pharmacokinetics.

Arora V, Devi GR, Iversen PL.

Curr Pharm Biotechnol. 2004 Oct;5(5):431-9.

PMID:
15544491
[PubMed - indexed for MEDLINE]
15.

Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models.

Burrer R, Neuman BW, Ting JP, Stein DA, Moulton HM, Iversen PL, Kuhn P, Buchmeier MJ.

J Virol. 2007 Jun;81(11):5637-48. Epub 2007 Mar 7.

PMID:
17344287
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Arginine-rich cell-penetrating peptides facilitate delivery of antisense oligomers into murine leukocytes and alter pre-mRNA splicing.

Marshall NB, Oda SK, London CA, Moulton HM, Iversen PL, Kerkvliet NI, Mourich DV.

J Immunol Methods. 2007 Aug 31;325(1-2):114-26. Epub 2007 Jul 27.

PMID:
17673254
[PubMed - indexed for MEDLINE]
17.

Phosphorodiamidate morpholino antisense oligomers inhibit expression of human cytochrome P450 3A4 and alter selected drug metabolism.

Arora V, Cate ML, Ghosh C, Iversen PL.

Drug Metab Dispos. 2002 Jul;30(7):757-62.

PMID:
12065433
[PubMed - indexed for MEDLINE]
Free Article
18.

Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate.

Amantana A, Moulton HM, Cate ML, Reddy MT, Whitehead T, Hassinger JN, Youngblood DS, Iversen PL.

Bioconjug Chem. 2007 Jul-Aug;18(4):1325-31. Epub 2007 Jun 21.

PMID:
17583927
[PubMed - indexed for MEDLINE]
19.

In vivo bioavailability and pharmacokinetics of a c-MYC antisense phosphorodiamidate morpholino oligomer, AVI-4126, in solid tumors.

Devi GR, Beer TM, Corless CL, Arora V, Weller DL, Iversen PL.

Clin Cancer Res. 2005 May 15;11(10):3930-8.

PMID:
15897595
[PubMed - indexed for MEDLINE]
Free Article
20.

Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers.

Neuman BW, Stein DA, Kroeker AD, Churchill MJ, Kim AM, Kuhn P, Dawson P, Moulton HM, Bestwick RK, Iversen PL, Buchmeier MJ.

J Virol. 2005 Aug;79(15):9665-76.

PMID:
16014928
[PubMed - indexed for MEDLINE]
Free PMC Article

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