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Results: 1 to 20 of 98

1.

ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients.

Baena E, Shao Z, Linn DE, Glass K, Hamblen MJ, Fujiwara Y, Kim J, Nguyen M, Zhang X, Godinho FJ, Bronson RT, Mucci LA, Loda M, Yuan GC, Orkin SH, Li Z.

Genes Dev. 2013 Mar 15;27(6):683-98. doi: 10.1101/gad.211011.112.

PMID:
23512661
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss.

Chen Y, Chi P, Rockowitz S, Iaquinta PJ, Shamu T, Shukla S, Gao D, Sirota I, Carver BS, Wongvipat J, Scher HI, Zheng D, Sawyers CL.

Nat Med. 2013 Aug;19(8):1023-9. doi: 10.1038/nm.3216. Epub 2013 Jun 30.

PMID:
23817021
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer.

Tomlins SA, Laxman B, Dhanasekaran SM, Helgeson BE, Cao X, Morris DS, Menon A, Jing X, Cao Q, Han B, Yu J, Wang L, Montie JE, Rubin MA, Pienta KJ, Roulston D, Shah RB, Varambally S, Mehra R, Chinnaiyan AM.

Nature. 2007 Aug 2;448(7153):595-9.

PMID:
17671502
[PubMed - indexed for MEDLINE]
5.

Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81.

Shin S, Kim TD, Jin F, van Deursen JM, Dehm SM, Tindall DJ, Grande JP, Munz JM, Vasmatzis G, Janknecht R.

Cancer Res. 2009 Oct 15;69(20):8102-10. doi: 10.1158/0008-5472.CAN-09-0941. Epub 2009 Sep 29.

PMID:
19789348
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion.

Cai C, Hsieh CL, Omwancha J, Zheng Z, Chen SY, Baert JL, Shemshedini L.

Mol Endocrinol. 2007 Aug;21(8):1835-46. Epub 2007 May 15.

PMID:
17505060
[PubMed - indexed for MEDLINE]
7.

ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells.

Zong Y, Xin L, Goldstein AS, Lawson DA, Teitell MA, Witte ON.

Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12465-70. doi: 10.1073/pnas.0905931106. Epub 2009 Jul 10.

PMID:
19592505
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion.

Rahim S, Beauchamp EM, Kong Y, Brown ML, Toretsky JA, Üren A.

PLoS One. 2011 Apr 29;6(4):e19343. doi: 10.1371/journal.pone.0019343.

PMID:
21559405
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao X, Tchinda J, Kuefer R, Lee C, Montie JE, Shah RB, Pienta KJ, Rubin MA, Chinnaiyan AM.

Science. 2005 Oct 28;310(5748):644-8.

PMID:
16254181
[PubMed - indexed for MEDLINE]
Free Article
10.

Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer.

Reid AH, Attard G, Ambroisine L, Fisher G, Kovacs G, Brewer D, Clark J, Flohr P, Edwards S, Berney DM, Foster CS, Fletcher A, Gerald WL, Møller H, Reuter VE, Scardino PT, Cuzick J, de Bono JS, Cooper CS; Transatlantic Prostate Group.

Br J Cancer. 2010 Feb 16;102(4):678-84. doi: 10.1038/sj.bjc.6605554. Epub 2010 Jan 26.

PMID:
20104229
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer.

Hermans KG, van Marion R, van Dekken H, Jenster G, van Weerden WM, Trapman J.

Cancer Res. 2006 Nov 15;66(22):10658-63.

PMID:
17108102
[PubMed - indexed for MEDLINE]
Free Article
12.

Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer.

Mehra R, Tomlins SA, Shen R, Nadeem O, Wang L, Wei JT, Pienta KJ, Ghosh D, Rubin MA, Chinnaiyan AM, Shah RB.

Mod Pathol. 2007 May;20(5):538-44. Epub 2007 Mar 2.

PMID:
17334343
[PubMed - indexed for MEDLINE]
Free Article
13.

COP1 is a tumour suppressor that causes degradation of ETS transcription factors.

Vitari AC, Leong KG, Newton K, Yee C, O'Rourke K, Liu J, Phu L, Vij R, Ferrando R, Couto SS, Mohan S, Pandita A, Hongo JA, Arnott D, Wertz IE, Gao WQ, French DM, Dixit VM.

Nature. 2011 May 15;474(7351):403-6. doi: 10.1038/nature10005.

PMID:
21572435
[PubMed - indexed for MEDLINE]
14.

Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer.

Mehra R, Tomlins SA, Yu J, Cao X, Wang L, Menon A, Rubin MA, Pienta KJ, Shah RB, Chinnaiyan AM.

Cancer Res. 2008 May 15;68(10):3584-90. doi: 10.1158/0008-5472.CAN-07-6154.

PMID:
18483239
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model.

Leshem O, Madar S, Kogan-Sakin I, Kamer I, Goldstein I, Brosh R, Cohen Y, Jacob-Hirsch J, Ehrlich M, Ben-Sasson S, Goldfinger N, Loewenthal R, Gazit E, Rotter V, Berger R.

PLoS One. 2011;6(7):e21650. doi: 10.1371/journal.pone.0021650. Epub 2011 Jul 1.

PMID:
21747944
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells.

Shin S, Oh S, An S, Janknecht R.

Oncol Rep. 2013 Jan;29(1):306-14. doi: 10.3892/or.2012.2079. Epub 2012 Oct 16.

PMID:
23076342
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions.

Cerveira N, Ribeiro FR, Peixoto A, Costa V, Henrique R, Jerónimo C, Teixeira MR.

Neoplasia. 2006 Oct;8(10):826-32.

PMID:
17032499
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

ETS rearrangements and prostate cancer initiation.

Carver BS, Tran J, Chen Z, Carracedo-Perez A, Alimonti A, Nardella C, Gopalan A, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP.

Nature. 2009 Feb 12;457(7231):E1; discussion E2-3. doi: 10.1038/nature07738.

PMID:
19212347
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Inactivation of AR/TMPRSS2-ERG/Wnt signaling networks attenuates the aggressive behavior of prostate cancer cells.

Li Y, Kong D, Wang Z, Ahmad A, Bao B, Padhye S, Sarkar FH.

Cancer Prev Res (Phila). 2011 Sep;4(9):1495-506. doi: 10.1158/1940-6207.CAPR-11-0077. Epub 2011 Jun 16.

PMID:
21680704
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Bioinformatics approach leads to the discovery of the TMPRSS2:ETS gene fusion in prostate cancer.

Rubin MA, Chinnaiyan AM.

Lab Invest. 2006 Nov;86(11):1099-102. Epub 2006 Sep 18.

PMID:
16983328
[PubMed - indexed for MEDLINE]
Free Article

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