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Items: 1 to 20 of 122

1.

Rutaecarpine effects on expression of hepatic phase-1, phase-2 metabolism and transporter genes as a basis of herb-drug interactions.

Zhu QN, Zhang D, Jin T, Wu Q, Liu J, Lu YF.

J Ethnopharmacol. 2013 May 2;147(1):215-9. doi: 10.1016/j.jep.2013.03.005. Epub 2013 Mar 16.

PMID:
23510861
2.

Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPAR╬▒-, and Nrf2-null mice.

Aleksunes LM, Klaassen CD.

Drug Metab Dispos. 2012 Jul;40(7):1366-79. doi: 10.1124/dmd.112.045112. Epub 2012 Apr 11.

3.

Induction of cytochrome P450s by rutaecarpine and metabolism of rutaecarpine by cytochrome P450s.

Lee SK, Kim NH, Lee J, Kim DH, Lee ES, Choi HG, Chang HW, Jahng Y, Jeong TC.

Planta Med. 2004 Aug;70(8):753-7.

PMID:
15326550
4.
5.

Modulation of drug-metabolizing enzymes by extracts of a herbal medicine Evodia rutaecarpa in C57BL/6J mice.

Ueng YF, Ko HC, Chen CF, Wang JJ, Chen KT.

Life Sci. 2002 Aug 2;71(11):1267-77.

PMID:
12106592
6.

Effects of rutaecarpine on the metabolism and urinary excretion of caffeine in rats.

Noh K, Seo YM, Lee SK, Bista SR, Kang MJ, Jahng Y, Kim E, Kang W, Jeong TC.

Arch Pharm Res. 2011 Jan;34(1):119-25. doi: 10.1007/s12272-011-0114-3. Epub 2011 Apr 6.

PMID:
21468923
7.

Effect of interferon-╬▒2b on the expression of various drug-metabolizing enzymes and transporters in co-cultures of freshly prepared human primary hepatocytes.

Chen C, Han YH, Yang Z, Rodrigues AD.

Xenobiotica. 2011 Jun;41(6):476-85. doi: 10.3109/00498254.2011.560971. Epub 2011 Mar 7.

PMID:
21381897
8.

Alteration of the pharmacokinetics of theophylline by rutaecarpine, an alkaloid of the medicinal herb Evodia rutaecarpa, in rats.

Ueng YF, Tsai TH, Don MJ, Chen RM, Chen TL.

J Pharm Pharmacol. 2005 Feb;57(2):227-32.

PMID:
15720787
9.

The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes.

Ueng YF, Jan WC, Lin LC, Chen TL, Guengerich FP, Chen CF.

Drug Metab Dispos. 2002 Mar;30(3):349-53.

10.

In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor.

Reese MJ, Savina PM, Generaux GT, Tracey H, Humphreys JE, Kanaoka E, Webster LO, Harmon KA, Clarke JD, Polli JW.

Drug Metab Dispos. 2013 Feb;41(2):353-61. doi: 10.1124/dmd.112.048918. Epub 2012 Nov 6.

11.

Dose-response of berberine on hepatic cytochromes P450 mRNA expression and activities in mice.

Guo Y, Pope C, Cheng X, Zhou H, Klaassen CD.

J Ethnopharmacol. 2011 Oct 31;138(1):111-8. doi: 10.1016/j.jep.2011.08.058. Epub 2011 Sep 6.

12.

Induction of NAD(P)H: quinone reductase by rutaecarpine isolated from the fruits of Evodia rutaecarpa in the murine hepatic Hepa-1c1c7 cell line.

Ahn H, Nam JW, Seo EK, Mar W.

Planta Med. 2008 Sep;74(11):1387-90. doi: 10.1055/s-2008-1081329. Epub 2008 Aug 26.

PMID:
18729042
13.

Alterations in hepatic mRNA expression of phase II enzymes and xenobiotic transporters after targeted disruption of hepatocyte nuclear factor 4 alpha.

Lu H, Gonzalez FJ, Klaassen C.

Toxicol Sci. 2010 Dec;118(2):380-90. doi: 10.1093/toxsci/kfq280. Epub 2010 Oct 8.

14.
15.

Induction of hepatic phase II drug-metabolizing enzymes by 1,7-phenanthroline in rats is accompanied by induction of MRP3.

Wang S, Hartley DP, Ciccotto SL, Vincent SH, Franklin RB, Kim MS.

Drug Metab Dispos. 2003 Jun;31(6):773-5.

16.

Gestational age-dependent changes in gene expression of metabolic enzymes and transporters in pregnant mice.

Shuster DL, Bammler TK, Beyer RP, Macdonald JW, Tsai JM, Farin FM, Hebert MF, Thummel KE, Mao Q.

Drug Metab Dispos. 2013 Feb;41(2):332-42. doi: 10.1124/dmd.112.049718. Epub 2012 Nov 21. Erratum in: Drug Metab Dispos. 2013 Mar;41(3):682.

17.

Up-regulation of CYP1A1 by rutaecarpine is dependent on aryl hydrocarbon receptor and calcium.

Han EH, Kim HG, Im JH, Jeong TC, Jeong HG.

Toxicology. 2009 Dec 21;266(1-3):38-47. doi: 10.1016/j.tox.2009.10.013. Epub 2009 Oct 21.

PMID:
19853001
18.

Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver.

Wu KC, Cui JY, Klaassen CD.

PLoS One. 2012;7(7):e39006. doi: 10.1371/journal.pone.0039006. Epub 2012 Jul 12.

19.

The effects of rutaecarpine on the pharmacokinetics of acetaminophen in rats.

Lee SK, Bista SR, Jeong H, Kim DH, Kang MJ, Jahng Y, Jeong TC.

Arch Pharm Res. 2007 Dec;30(12):1629-34.

PMID:
18254252
20.

Short-term exposure to triclosan decreases thyroxine in vivo via upregulation of hepatic catabolism in Young Long-Evans rats.

Paul KB, Hedge JM, DeVito MJ, Crofton KM.

Toxicol Sci. 2010 Feb;113(2):367-79. doi: 10.1093/toxsci/kfp271. Epub 2009 Nov 12.

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