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Results: 1 to 20 of 116

1.

Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features.

Schwab CJ, Chilton L, Morrison H, Jones L, Al-Shehhi H, Erhorn A, Russell LJ, Moorman AV, Harrison CJ.

Haematologica. 2013 Jul;98(7):1081-8. doi: 10.3324/haematol.2013.085175. Epub 2013 Mar 18.

PMID:
23508010
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia.

Schwab CJ, Jones LR, Morrison H, Ryan SL, Yigittop H, Schouten JP, Harrison CJ.

Genes Chromosomes Cancer. 2010 Dec;49(12):1104-13. doi: 10.1002/gcc.20818.

PMID:
20815030
[PubMed - indexed for MEDLINE]
3.

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

Mullighan CG, Su X, Zhang J, Radtke I, Phillips LA, Miller CB, Ma J, Liu W, Cheng C, Schulman BA, Harvey RC, Chen IM, Clifford RJ, Carroll WL, Reaman G, Bowman WP, Devidas M, Gerhard DS, Yang W, Relling MV, Shurtleff SA, Campana D, Borowitz MJ, Pui CH, Smith M, Hunger SP, Willman CL, Downing JR; Children's Oncology Group.

N Engl J Med. 2009 Jan 29;360(5):470-80. doi: 10.1056/NEJMoa0808253. Epub 2009 Jan 7.

PMID:
19129520
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia.

Moorman AV, Schwab C, Ensor HM, Russell LJ, Morrison H, Jones L, Masic D, Patel B, Rowe JM, Tallman M, Goldstone AH, Fielding AK, Harrison CJ.

J Clin Oncol. 2012 Sep 1;30(25):3100-8. doi: 10.1200/JCO.2011.40.3907. Epub 2012 Jul 30.

PMID:
22851563
[PubMed - indexed for MEDLINE]
5.

Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.

van der Veer A, Waanders E, Pieters R, Willemse ME, Van Reijmersdal SV, Russell LJ, Harrison CJ, Evans WE, van der Velden VH, Hoogerbrugge PM, Van Leeuwen F, Escherich G, Horstmann MA, Mohammadi Khankahdani L, Rizopoulos D, De Groot-Kruseman HA, Sonneveld E, Kuiper RP, Den Boer ML.

Blood. 2013 Oct 10;122(15):2622-9. doi: 10.1182/blood-2012-10-462358. Epub 2013 Aug 23.

PMID:
23974192
[PubMed - indexed for MEDLINE]
6.

IKZF1 and CRLF2 gene alterations correlate with poor prognosis in Japanese BCR-ABL1-negative high-risk B-cell precursor acute lymphoblastic leukemia.

Yamashita Y, Shimada A, Yamada T, Yamaji K, Hori T, Tsurusawa M, Watanabe A, Kikuta A, Asami K, Saito AM, Horibe K.

Pediatr Blood Cancer. 2013 Oct;60(10):1587-92. doi: 10.1002/pbc.24571. Epub 2013 Jun 27.

PMID:
23804397
[PubMed - indexed for MEDLINE]
7.

What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?

Palmi C, Valsecchi MG, Longinotti G, Silvestri D, Carrino V, Conter V, Basso G, Biondi A, Kronnie GT, Cazzaniga G.

Haematologica. 2013 Aug;98(8):1226-31. doi: 10.3324/haematol.2012.075432. Epub 2013 Apr 12.

PMID:
23585525
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL.

Kuiper RP, Waanders E, van der Velden VH, van Reijmersdal SV, Venkatachalam R, Scheijen B, Sonneveld E, van Dongen JJ, Veerman AJ, van Leeuwen FN, van Kessel AG, Hoogerbrugge PM.

Leukemia. 2010 Jul;24(7):1258-64. doi: 10.1038/leu.2010.87. Epub 2010 May 6.

PMID:
20445578
[PubMed - indexed for MEDLINE]
9.

Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia.

Caye A, Beldjord K, Mass-Malo K, Drunat S, Soulier J, Gandemer V, Baruchel A, Bertrand Y, Cavé H, Clappier E.

Haematologica. 2013 Apr;98(4):597-601. doi: 10.3324/haematol.2012.073965. Epub 2012 Oct 12.

PMID:
23065506
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Molecular inversion probes reveal patterns of 9p21 deletion and copy number aberrations in childhood leukemia.

Schiffman JD, Wang Y, McPherson LA, Welch K, Zhang N, Davis R, Lacayo NJ, Dahl GV, Faham M, Ford JM, Ji HP.

Cancer Genet Cytogenet. 2009 Aug;193(1):9-18. doi: 10.1016/j.cancergencyto.2009.03.005.

PMID:
19602459
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011.

Olsson L, Castor A, Behrendtz M, Biloglav A, Forestier E, Paulsson K, Johansson B.

Leukemia. 2014 Feb;28(2):302-10. doi: 10.1038/leu.2013.206. Epub 2013 Jul 4.

PMID:
23823658
[PubMed - indexed for MEDLINE]
12.

IKZF1 deletion is associated with a poor outcome in pediatric B-cell precursor acute lymphoblastic leukemia in Japan.

Asai D, Imamura T, Suenobu S, Saito A, Hasegawa D, Deguchi T, Hashii Y, Matsumoto K, Kawasaki H, Hori H, Iguchi A, Kosaka Y, Kato K, Horibe K, Yumura-Yagi K, Hara J, Oda M; Japan Association of Childhood Leukemia Study (JACLS).

Cancer Med. 2013 Jun;2(3):412-9. doi: 10.1002/cam4.87. Epub 2013 May 9.

PMID:
23930217
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Impact of IKZF1 deletions on IKZF1 expression and outcome in Philadelphia chromosome negative childhood BCP-ALL. Reply to "incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philadelphia chromosome positive B-cell precursor acute lymphoblastic leukemia".

Palmi C, Lana T, Silvestri D, Savino A, Kronnie GT, Conter V, Basso G, Biondi A, Valsecchi MG, Cazzaniga G.

Haematologica. 2013 Dec;98(12):e164-5. doi: 10.3324/haematol.2013.099077. No abstract available.

PMID:
24323991
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia.

Rand V, Parker H, Russell LJ, Schwab C, Ensor H, Irving J, Jones L, Masic D, Minto L, Morrison H, Ryan S, Robinson H, Sinclair P, Moorman AV, Strefford JC, Harrison CJ.

Blood. 2011 Jun 23;117(25):6848-55. doi: 10.1182/blood-2011-01-329961. Epub 2011 Apr 28.

PMID:
21527530
[PubMed - indexed for MEDLINE]
Free Article
15.

The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party.

Iacobucci I, Lonetti A, Paoloni F, Papayannidis C, Ferrari A, Storlazzi CT, Vignetti M, Cilloni D, Messa F, Guadagnuolo V, Paolini S, Elia L, Messina M, Vitale A, Meloni G, Soverini S, Pane F, Baccarani M, Foà R, Martinelli G.

Haematologica. 2010 Oct;95(10):1683-90. doi: 10.3324/haematol.2009.020792. Epub 2010 Jun 9.

PMID:
20534699
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions.

Clappier E, Auclerc MF, Rapion J, Bakkus M, Caye A, Khemiri A, Giroux C, Hernandez L, Kabongo E, Savola S, Leblanc T, Yakouben K, Plat G, Costa V, Ferster A, Girard S, Fenneteau O, Cayuela JM, Sigaux F, Dastugue N, Suciu S, Benoit Y, Bertrand Y, Soulier J, Cavé H.

Leukemia. 2014 Jan;28(1):70-7. doi: 10.1038/leu.2013.277. Epub 2013 Sep 25.

PMID:
24064621
[PubMed - indexed for MEDLINE]
17.

Impact of IKZF1 deletions and PAX5 amplifications in pediatric B-cell precursor ALL treated according to NOPHO protocols.

Ofverholm I, Tran AN, Heyman M, Zachariadis V, Nordenskjöld M, Nordgren A, Barbany G.

Leukemia. 2013 Sep;27(9):1936-9. doi: 10.1038/leu.2013.92. Epub 2013 Mar 29. No abstract available.

PMID:
23538749
[PubMed - indexed for MEDLINE]
18.

High frequency of IKZF1 genetic alterations in adult patients with B-cell acute lymphoblastic leukemia.

Tokunaga K, Yamaguchi S, Iwanaga E, Nanri T, Shimomura T, Suzushima H, Mitsuya H, Asou N.

Eur J Haematol. 2013 Sep;91(3):201-8. doi: 10.1111/ejh.12155. Epub 2013 Jul 7.

PMID:
23751147
[PubMed - indexed for MEDLINE]
19.

Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations.

Buitenkamp TD, Pieters R, Gallimore NE, van der Veer A, Meijerink JP, Beverloo HB, Zimmermann M, de Haas V, Richards SM, Vora AJ, Mitchell CD, Russell LJ, Schwab C, Harrison CJ, Moorman AV, van den Heuvel-Eibrink MM, den Boer ML, Zwaan CM.

Leukemia. 2012 Oct;26(10):2204-11. doi: 10.1038/leu.2012.84. Epub 2012 Mar 22.

PMID:
22441210
[PubMed - indexed for MEDLINE]
20.

IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan.

Yang YL, Hung CC, Chen JS, Lin KH, Jou ST, Hsiao CC, Sheen JM, Cheng CN, Wu KH, Lin SR, Yu SL, Chen HY, Lu MY, Wang SC, Chang HH, Lin SW, Su YN, Lin DT.

Cancer Sci. 2011 Oct;102(10):1874-81. doi: 10.1111/j.1349-7006.2011.02031.x. Epub 2011 Aug 12.

PMID:
21740479
[PubMed - indexed for MEDLINE]

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