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Items: 1 to 20 of 92

1.

PRSS3/mesotrypsin in prostate cancer progression: implications for translational medicine.

Radisky ES.

Asian J Androl. 2013 Jul;15(4):439-40. doi: 10.1038/aja.2013.14. Epub 2013 Mar 18. No abstract available.

2.

PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.

Hockla A, Miller E, Salameh MA, Copland JA, Radisky DC, Radisky ES.

Mol Cancer Res. 2012 Dec;10(12):1555-66. doi: 10.1158/1541-7786.MCR-12-0314.

3.

The P(2)' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity.

Salameh MA, Soares AS, Hockla A, Radisky DC, Radisky ES.

Biochem J. 2011 Nov 15;440(1):95-105. doi: 10.1042/BJ20110788.

4.

Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors.

Salameh MA, Soares AS, Alloy A, Radisky ES.

Protein Sci. 2012 Aug;21(8):1103-12. doi: 10.1002/pro.2097. Epub 2012 Jun 25.

5.

Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors.

Szmola R, Kukor Z, Sahin-Tóth M.

J Biol Chem. 2003 Dec 5;278(49):48580-9. Epub 2003 Sep 24.

6.
7.

Complete analysis of the human mesotrypsinogen gene (PRSS3) in patients with chronic pancreatitis.

Rosendahl J, Teich N, Kovacs P, Szmola R, Blüher M, Gress TM, Hoffmeister A, Keim V, Löhr M, Mössner J, Nickel R, Ockenga J, Pfützer R, Schulz HU, Stumvoll M, Wittenburg H, Sahin-Tóth M, Witt H.

Pancreatology. 2010;10(2-3):243-9. doi: 10.1159/000243769. Epub 2010 May 13.

8.
9.

Effect of low-molecular weight trypsin inhibitor, nafamostat mesilate, on trypsin activity using the pancreatic acinar cells.

Hashimoto D, Ohmuraya M, Wang J, Yamamura K, Hirota M, Baba H.

Pancreas. 2009 Jul;38(5):595-7. doi: 10.1097/MPA.0b013e31819156de. No abstract available.

PMID:
19550278
10.

Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.

Knecht W, Cottrell GS, Amadesi S, Mohlin J, Skåregärde A, Gedda K, Peterson A, Chapman K, Hollenberg MD, Vergnolle N, Bunnett NW.

J Biol Chem. 2007 Sep 7;282(36):26089-100. Epub 2007 Jul 10.

11.

Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin.

Salameh MA, Soares AS, Hockla A, Radisky ES.

J Biol Chem. 2008 Feb 15;283(7):4115-23. Epub 2007 Dec 12.

12.
13.

Proceedings: Modification of trypsin activity by anti-inflammatory drugs.

Baillie AJ, Anderson W.

J Pharm Pharmacol. 1974 Dec;26 Suppl:117P-118P. No abstract available.

PMID:
4156711
14.

The reaction of alpha 2-macroglobulin-bound trypsin with soybean trypsin inhibitor.

Wang D, Wu K, Feinman RD.

J Biol Chem. 1981 Nov 10;256(21):10934-40. No abstract available.

15.

Mesotrypsin, a brain trypsin, activates selectively proteinase-activated receptor-1, but not proteinase-activated receptor-2, in rat astrocytes.

Wang Y, Luo W, Wartmann T, Halangk W, Sahin-Tóth M, Reiser G.

J Neurochem. 2006 Nov;99(3):759-69. Epub 2006 Aug 11.

16.

A comparison of the inhibition kinetics of trypsin in free solution and trypsin coupled to Sepharose-4B.

Steven FS, Griffin MM.

Biochem Soc Trans. 1981 Feb;9(1):145-6. No abstract available.

PMID:
7215648
17.

Reevaluation of the role of early trypsin activity in the transcriptional activation of the late trypsin gene in the mosquito Aedes aegypti.

Lu SJ, Pennington JE, Stonehouse AR, Mobula MM, Wells MA.

Insect Biochem Mol Biol. 2006 Apr;36(4):336-43. Epub 2006 Jan 19.

PMID:
16551547
18.

Detection and partial characterization of a protein in mouse fibroblasts that binds and inhibits trypsin.

Kirschner RJ, Federiuk CS, Ford JP, Shafer JA.

J Biol Chem. 1980 Jun 10;255(11):5468-74. No abstract available.

19.

Effect of pea and bovine trypsin inhibitors on wild-type and modified trypsins.

Pouvreau L, Chobert JM, Briand L, Quillien L, Tran V, Guéguen J, Haertlé T.

FEBS Lett. 1998 Feb 20;423(2):167-72.

20.

Mesotrypsin: a new inhibitor-resistant protease from a zymogen in human pancreatic tissue and fluid.

Rinderknecht H, Renner IG, Abramson SB, Carmack C.

Gastroenterology. 1984 Apr;86(4):681-92.

PMID:
6698368
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