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The resolving power of in vitro genotoxicity assays for cigarette smoke particulate matter.

Scott K, Saul J, Crooks I, Camacho OM, Dillon D, Meredith C.

Toxicol In Vitro. 2013 Jun;27(4):1312-9. doi: 10.1016/j.tiv.2013.02.015. Epub 2013 Mar 7.


The mutagenic assessment of mainstream cigarette smoke using the Ames assay: a multi-strain approach.

Thorne D, Kilford J, Hollings M, Dalrymple A, Ballantyne M, Meredith C, Dillon D.

Mutat Res Genet Toxicol Environ Mutagen. 2015 Apr;782:9-17. doi: 10.1016/j.mrgentox.2015.03.006. Epub 2015 Mar 5.


The combination of two novel tobacco blends and filter technologies to reduce the in vitro genotoxicity and cytotoxicity of prototype cigarettes.

Crooks I, Scott K, Dalrymple A, Dillon D, Meredith C.

Regul Toxicol Pharmacol. 2015 Apr;71(3):507-14. doi: 10.1016/j.yrtph.2015.01.001. Epub 2015 Jan 10.


A method for assessment of the genotoxicity of mainstream cigarette-smoke by use of the bacterial reverse-mutation assay and an aerosol-based exposure system.

Kilford J, Thorne D, Payne R, Dalrymple A, Clements J, Meredith C, Dillon D.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Jul 15;769:20-8. doi: 10.1016/j.mrgentox.2014.04.017. Epub 2014 May 13.


Characterisation of an aerosol exposure system to evaluate the genotoxicity of whole mainstream cigarette smoke using the in vitro γH2AX assay by high content screening.

Garcia-Canton C, Errington G, Anadon A, Meredith C.

BMC Pharmacol Toxicol. 2014 Jul 23;15:41. doi: 10.1186/2050-6511-15-41.


A comprehensive evaluation of the toxicology of monogram inks added to experimental cigarettes.

Smith DC, Wiecinski PN, Coggins CR, Banty TH, Oldham MJ.

Inhal Toxicol. 2013;25 Suppl 2:34-45. doi: 10.3109/08958378.2013.854432.


Comparison of in vitro toxicity of mainstream cigarette smoke particulate matter from nano- to micro-size.

Lin B, Li X, Zhang H, Lin Z, Tian L, Nie C, Fang Y, Xi Z.

Food Chem Toxicol. 2014 Feb;64:353-60. doi: 10.1016/j.fct.2013.12.007. Epub 2013 Dec 12.


Characterisation of a Vitrocell® VC 10 in vitro smoke exposure system using dose tools and biological analysis.

Thorne D, Kilford J, Payne R, Adamson J, Scott K, Dalrymple A, Meredith C, Dillon D.

Chem Cent J. 2013 Sep 3;7(1):146. doi: 10.1186/1752-153X-7-146.


In vitro micronucleus assay for the analysis of total particulate matter in cigarette smoke: comparison of flow cytometry and laser scanning cytometry with microscopy.

Yao J, Gao Q, Mi Q, Li X, Miao M, Cheng P, Luo Y.

Mutat Res. 2013 Aug 15;755(2):120-5. doi: 10.1016/j.mrgentox.2013.05.017. Epub 2013 Jun 14.


The in vitro cytotoxicity and genotoxicity of cigarette smoke particulate matter with reduced toxicant yields.

Combes R, Scott K, Crooks I, Dillon D, Meredith C, McAdam K, Proctor C.

Toxicol In Vitro. 2013 Aug;27(5):1533-41. doi: 10.1016/j.tiv.2013.03.005. Epub 2013 Mar 27.


The effect of long term storage on tobacco smoke particulate matter in in vitro genotoxicity and cytotoxicity assays.

Crooks I, Dillon DM, Scott JK, Ballantyne M, Meredith C.

Regul Toxicol Pharmacol. 2013 Mar;65(2):196-200. doi: 10.1016/j.yrtph.2012.11.012. Epub 2012 Dec 6.


The effect of a novel tobacco process on the in vitro cytotoxicity and genotoxicity of cigarette smoke particulate matter.

Combes R, Scott K, Dillon D, Meredith C, McAdam K, Proctor C.

Toxicol In Vitro. 2012 Sep;26(6):1022-9. doi: 10.1016/j.tiv.2012.04.011. Epub 2012 Apr 20.


Mutagenicity and clastogenicity evaluation of tacrine by Ames and micronucleus assays.

Mulla MS, Vedamurthy RB, Jana S, Pandey SK, Goyal VK, Nirogi R.

Drug Chem Toxicol. 2012 Oct;35(4):366-70. doi: 10.3109/01480545.2011.627865. Epub 2011 Dec 19.


Genotoxicity of silver nanoparticles evaluated using the Ames test and in vitro micronucleus assay.

Li Y, Chen DH, Yan J, Chen Y, Mittelstaedt RA, Zhang Y, Biris AS, Heflich RH, Chen T.

Mutat Res. 2012 Jun 14;745(1-2):4-10. doi: 10.1016/j.mrgentox.2011.11.010. Epub 2011 Nov 26.


Mutagenicity and genotoxicity of suspended particulate matter in the Seine river estuary.

Vincent-Hubert F, Heas-Moisan K, Munschy C, Tronczynski J.

Mutat Res. 2012 Jan 24;741(1-2):7-12. doi: 10.1016/j.mrgentox.2011.09.019. Epub 2011 Nov 4.


De-Risking of Stilbazulenyl Nitrone (STAZN), a Lipophilic Nitrone to Treat Stroke Using a Unique Panel of In Vitro Assays.

Lapchak PA, Schubert DR, Maher PA.

Transl Stroke Res. 2011 Jun;2(2):209-17. doi: 10.1007/s12975-011-0071-7.


Mutagenic, cytotoxic, and genotoxic properties of tobacco smoke produced by cigarillos available on the Canadian market.

Rickert WS, Trivedi AH, Momin RA, Wagstaff WG, Lauterbach JH.

Regul Toxicol Pharmacol. 2011 Nov;61(2):199-209. doi: 10.1016/j.yrtph.2011.07.009. Epub 2011 Jul 29.


Evaluation of the genotoxic potential of single-wall carbon nanotubes by using a battery of in vitro and in vivo genotoxicity assays.

Naya M, Kobayashi N, Mizuno K, Matsumoto K, Ema M, Nakanishi J.

Regul Toxicol Pharmacol. 2011 Nov;61(2):192-8. doi: 10.1016/j.yrtph.2011.07.008. Epub 2011 Jul 29.


Analytical in vitro approach for studying cyto- and genotoxic effects of particulate airborne material.

Aufderheide M, Scheffler S, Möhle N, Halter B, Hochrainer D.

Anal Bioanal Chem. 2011 Dec;401(10):3213-20. doi: 10.1007/s00216-011-5163-4. Epub 2011 Jun 22.


A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins.

Kirkland D, Reeve L, Gatehouse D, Vanparys P.

Mutat Res. 2011 Mar 18;721(1):27-73. doi: 10.1016/j.mrgentox.2010.12.015. Epub 2011 Jan 14.

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