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Items: 1 to 20 of 133

1.

High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan.

Dellago H, Preschitz-Kammerhofer B, Terlecki-Zaniewicz L, Schreiner C, Fortschegger K, Chang MW, Hackl M, Monteforte R, Kühnel H, Schosserer M, Gruber F, Tschachler E, Scheideler M, Grillari-Voglauer R, Grillari J, Wieser M.

Aging Cell. 2013 Jun;12(3):446-58. doi: 10.1111/acel.12069. Epub 2013 Apr 19.

2.

MicroRNA 299-3p modulates replicative senescence in endothelial cells.

Jong HL, Mustafa MR, Vanhoutte PM, AbuBakar S, Wong PF.

Physiol Genomics. 2013 Apr 1;45(7):256-67. doi: 10.1152/physiolgenomics.00071.2012. Epub 2013 Jan 29.

3.

Upregulation of miR-760 and miR-186 is associated with replicative senescence in human lung fibroblast cells.

Lee YH, Kim SY, Bae YS.

Mol Cells. 2014 Aug;37(8):620-7. doi: 10.14348/molcells.2014.0157. Epub 2014 Aug 19.

4.
5.

CDK2 translational down-regulation during endothelial senescence.

Freedman DA, Folkman J.

Exp Cell Res. 2005 Jul 1;307(1):118-30. Epub 2005 Apr 21.

PMID:
15922732
6.

The mitochondrial lncRNA ASncmtRNA-2 is induced in aging and replicative senescence in Endothelial Cells.

Bianchessi V, Badi I, Bertolotti M, Nigro P, D'Alessandra Y, Capogrossi MC, Zanobini M, Pompilio G, Raucci A, Lauri A.

J Mol Cell Cardiol. 2015 Apr;81:62-70. doi: 10.1016/j.yjmcc.2015.01.012. Epub 2015 Jan 29.

PMID:
25640160
7.

Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells.

Sandhu C, Donovan J, Bhattacharya N, Stampfer M, Worland P, Slingerland J.

Oncogene. 2000 Nov 9;19(47):5314-23.

8.

MicroRNA regulation of ionizing radiation-induced premature senescence.

Wang Y, Scheiber MN, Neumann C, Calin GA, Zhou D.

Int J Radiat Oncol Biol Phys. 2011 Nov 1;81(3):839-48. doi: 10.1016/j.ijrobp.2010.09.048. Epub 2010 Nov 17.

9.

miR-29c-3p promotes senescence of human mesenchymal stem cells by targeting CNOT6 through p53-p21 and p16-pRB pathways.

Shang J, Yao Y, Fan X, Shangguan L, Li J, Liu H, Zhou Y.

Biochim Biophys Acta. 2016 Apr;1863(4):520-32. doi: 10.1016/j.bbamcr.2016.01.005. Epub 2016 Jan 11.

PMID:
26792405
10.

MicroRNA-23b regulates cyclin-dependent kinase-activating kinase complex through cyclin H repression to modulate endothelial transcription and growth under flow.

Wang KC, Nguyen P, Weiss A, Yeh YT, Chien HS, Lee A, Teng D, Subramaniam S, Li YS, Chien S.

Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1437-45. doi: 10.1161/ATVBAHA.114.303473. Epub 2014 May 22.

11.

The proto-oncogene LRF is under post-transcriptional control of MiR-20a: implications for senescence.

Poliseno L, Pitto L, Simili M, Mariani L, Riccardi L, Ciucci A, Rizzo M, Evangelista M, Mercatanti A, Pandolfi PP, Rainaldi G.

PLoS One. 2008 Jul 2;3(7):e2542. doi: 10.1371/journal.pone.0002542.

12.

MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by down-regulation of Cdc25A.

Sarkar S, Dey BK, Dutta A.

Mol Biol Cell. 2010 Jul 1;21(13):2138-49. doi: 10.1091/mbc.E10-01-0062. Epub 2010 May 12.

13.

Alterations in microRNA expression in stress-induced cellular senescence.

Li G, Luna C, Qiu J, Epstein DL, Gonzalez P.

Mech Ageing Dev. 2009 Nov-Dec;130(11-12):731-41. doi: 10.1016/j.mad.2009.09.002. Epub .

14.

KNDC1 knockdown protects human umbilical vein endothelial cells from senescence.

Zhang C, Zhen YZ, Lin YJ, Liu J, Wei J, Xu R, Hu G.

Mol Med Rep. 2014 Jul;10(1):82-8. doi: 10.3892/mmr.2014.2201. Epub 2014 Apr 30.

15.

miR-22 represses cancer progression by inducing cellular senescence.

Xu D, Takeshita F, Hino Y, Fukunaga S, Kudo Y, Tamaki A, Matsunaga J, Takahashi RU, Takata T, Shimamoto A, Ochiya T, Tahara H.

J Cell Biol. 2011 Apr 18;193(2):409-24. doi: 10.1083/jcb.201010100.

16.

MicroRNA-10A* and MicroRNA-21 modulate endothelial progenitor cell senescence via suppressing high-mobility group A2.

Zhu S, Deng S, Ma Q, Zhang T, Jia C, Zhuo D, Yang F, Wei J, Wang L, Dykxhoorn DM, Hare JM, Goldschmidt-Clermont PJ, Dong C.

Circ Res. 2013 Jan 4;112(1):152-64. doi: 10.1161/CIRCRESAHA.112.280016. Epub 2012 Oct 16.

17.

Transcriptional regulation of the cyclin-dependent kinase inhibitor 1A (p21) gene by NFI in proliferating human cells.

Ouellet S, Vigneault F, Lessard M, Leclerc S, Drouin R, Guérin SL.

Nucleic Acids Res. 2006;34(22):6472-87. Epub 2006 Nov 27.

18.

Escape from p21-mediated oncogene-induced senescence leads to cell dedifferentiation and dependence on anti-apoptotic Bcl-xL and MCL1 proteins.

de Carné Trécesson S, Guillemin Y, Bélanger A, Bernard AC, Preisser L, Ravon E, Gamelin E, Juin P, Barré B, Coqueret O.

J Biol Chem. 2011 Apr 15;286(15):12825-38. doi: 10.1074/jbc.M110.186437. Epub 2011 Feb 3.

19.

Multiple microRNAs rescue from Ras-induced senescence by inhibiting p21(Waf1/Cip1).

Borgdorff V, Lleonart ME, Bishop CL, Fessart D, Bergin AH, Overhoff MG, Beach DH.

Oncogene. 2010 Apr 15;29(15):2262-71. doi: 10.1038/onc.2009.497. Epub 2010 Jan 25.

PMID:
20101223
20.

miR-125a-5p impairs endothelial cell angiogenesis in aging mice via RTEF-1 downregulation.

Che P, Liu J, Shan Z, Wu R, Yao C, Cui J, Zhu X, Wang J, Burnett MS, Wang S, Wang J.

Aging Cell. 2014 Oct;13(5):926-34. doi: 10.1111/acel.12252. Epub 2014 Jul 24.

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