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Results: 1 to 20 of 104

1.

Hippocampal metabolomics using ultrahigh-resolution mass spectrometry reveals neuroinflammation from Alzheimer's disease in CRND8 mice.

Lin S, Liu H, Kanawati B, Liu L, Dong J, Li M, Huang J, Schmitt-Kopplin P, Cai Z.

Anal Bioanal Chem. 2013 Jun;405(15):5105-17. doi: 10.1007/s00216-013-6825-1. Epub 2013 Mar 14.

PMID:
23494273
[PubMed - indexed for MEDLINE]
2.

Ultrahigh resolution mass spectrometry-based metabolic characterization reveals cerebellum as a disturbed region in two animal models.

Lin S, Kanawati B, Liu L, Witting M, Li M, Huang J, Schmitt-Kopplin P, Cai Z.

Talanta. 2014 Jan;118:45-53. doi: 10.1016/j.talanta.2013.09.019. Epub 2013 Oct 5.

PMID:
24274269
[PubMed - in process]
3.

A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease.

Salek RM, Xia J, Innes A, Sweatman BC, Adalbert R, Randle S, McGowan E, Emson PC, Griffin JL.

Neurochem Int. 2010 Jul;56(8):937-47. doi: 10.1016/j.neuint.2010.04.001. Epub 2010 Apr 14.

PMID:
20398713
[PubMed - indexed for MEDLINE]
4.

Amyloid-beta protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice.

Lord A, Englund H, Söderberg L, Tucker S, Clausen F, Hillered L, Gordon M, Morgan D, Lannfelt L, Pettersson FE, Nilsson LN.

FEBS J. 2009 Feb;276(4):995-1006. doi: 10.1111/j.1742-4658.2008.06836.x.

PMID:
19215301
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition.

Chakrabarty P, Tianbai L, Herring A, Ceballos-Diaz C, Das P, Golde TE.

Mol Neurodegener. 2012 Jul 29;7:36. doi: 10.1186/1750-1326-7-36.

PMID:
22838967
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Changes in the physiology of CA1 hippocampal pyramidal neurons in preplaque CRND8 mice.

Wykes R, Kalmbach A, Eliava M, Waters J.

Neurobiol Aging. 2012 Aug;33(8):1609-23. doi: 10.1016/j.neurobiolaging.2011.05.001. Epub 2011 Jun 15.

PMID:
21676499
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease.

Fang F, Lue LF, Yan S, Xu H, Luddy JS, Chen D, Walker DG, Stern DM, Yan S, Schmidt AM, Chen JX, Yan SS.

FASEB J. 2010 Apr;24(4):1043-55. doi: 10.1096/fj.09-139634. Epub 2009 Nov 11.

PMID:
19906677
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A synthetic peptide blocking the apolipoprotein E/beta-amyloid binding mitigates beta-amyloid toxicity and fibril formation in vitro and reduces beta-amyloid plaques in transgenic mice.

Sadowski M, Pankiewicz J, Scholtzova H, Ripellino JA, Li Y, Schmidt SD, Mathews PM, Fryer JD, Holtzman DM, Sigurdsson EM, Wisniewski T.

Am J Pathol. 2004 Sep;165(3):937-48.

PMID:
15331417
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Role of hippocalcin in mediating Aβ toxicity.

Lim YA, Giese M, Shepherd C, Halliday G, Kobayashi M, Takamatsu K, Staufenbiel M, Eckert A, Götz J.

Biochim Biophys Acta. 2012 Aug;1822(8):1247-57. doi: 10.1016/j.bbadis.2012.04.007. Epub 2012 Apr 20.

PMID:
22542901
[PubMed - indexed for MEDLINE]
Free Article
10.

Effects of a tacrine-8-hydroxyquinoline hybrid (IQM-622) on Aβ accumulation and cell death: involvement in hippocampal neuronal loss in Alzheimer's disease.

Antequera D, Bolos M, Spuch C, Pascual C, Ferrer I, Fernandez-Bachiller MI, Rodríguez-Franco MI, Carro E.

Neurobiol Dis. 2012 Jun;46(3):682-91. doi: 10.1016/j.nbd.2012.03.009. Epub 2012 Mar 9.

PMID:
22426395
[PubMed - indexed for MEDLINE]
11.

Identification and structural characterisation of carboxy-terminal polypeptides and antibody epitopes of Alzheimer's amyloid precursor protein using high-resolution mass spectrometry.

Tian X, Cecal R, McLaurin J, Manea M, Stefanescu R, Grau S, Harnasch M, Amir S, Ehrmann M, St George-Hyslop P, Kohlmann M, Przybylski M.

Eur J Mass Spectrom (Chichester, Eng). 2005;11(5):547-56.

PMID:
16322661
[PubMed - indexed for MEDLINE]
12.

Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.

Zhang W, Hao J, Liu R, Zhang Z, Lei G, Su C, Miao J, Li Z.

Behav Brain Res. 2011 Sep 23;222(2):342-50. doi: 10.1016/j.bbr.2011.03.072. Epub 2011 Apr 14.

PMID:
21513747
[PubMed - indexed for MEDLINE]
13.

Metabolomics of transgenic maize combining Fourier transform-ion cyclotron resonance-mass spectrometry, capillary electrophoresis-mass spectrometry and pressurized liquid extraction.

Leon C, Rodriguez-Meizoso I, Lucio M, Garcia-Cañas V, Ibañez E, Schmitt-Kopplin P, Cifuentes A.

J Chromatogr A. 2009 Oct 23;1216(43):7314-23. doi: 10.1016/j.chroma.2009.04.092. Epub 2009 May 4.

PMID:
19477454
[PubMed - indexed for MEDLINE]
14.

Proteomic analysis of the brain tissues from a transgenic mouse model of amyloid β oligomers.

Takano M, Maekura K, Otani M, Sano K, Nakamura-Hirota T, Tokuyama S, Min KS, Tomiyama T, Mori H, Matsuyama S.

Neurochem Int. 2012 Aug;61(3):347-55. doi: 10.1016/j.neuint.2012.05.018. Epub 2012 May 23.

PMID:
22634250
[PubMed - indexed for MEDLINE]
15.

Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms.

Hartlage-Rübsamen M, Morawski M, Waniek A, Jäger C, Zeitschel U, Koch B, Cynis H, Schilling S, Schliebs R, Demuth HU, Rossner S.

Acta Neuropathol. 2011 Jun;121(6):705-19. doi: 10.1007/s00401-011-0806-2. Epub 2011 Feb 8.

PMID:
21301857
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Restraint stress increases neuroinflammation independently of amyloid β levels in amyloid precursor protein/PS1 transgenic mice.

Perez Nievas BG, Hammerschmidt T, Kummer MP, Terwel D, Leza JC, Heneka MT.

J Neurochem. 2011 Jan;116(1):43-52. doi: 10.1111/j.1471-4159.2010.07083.x. Epub 2010 Dec 2.

PMID:
21044080
[PubMed - indexed for MEDLINE]
17.

Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease.

Hernandez CM, Kayed R, Zheng H, Sweatt JD, Dineley KT.

J Neurosci. 2010 Feb 17;30(7):2442-53. doi: 10.1523/JNEUROSCI.5038-09.2010.

PMID:
20164328
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease.

Trushina E, Nemutlu E, Zhang S, Christensen T, Camp J, Mesa J, Siddiqui A, Tamura Y, Sesaki H, Wengenack TM, Dzeja PP, Poduslo JF.

PLoS One. 2012;7(2):e32737. doi: 10.1371/journal.pone.0032737. Epub 2012 Feb 29.

PMID:
22393443
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice.

Overk CR, Lu PY, Wang YT, Choi J, Shaw JW, Thatcher GR, Mufson EJ.

Neurobiol Dis. 2012 Jan;45(1):479-87. doi: 10.1016/j.nbd.2011.08.035. Epub 2011 Sep 16.

PMID:
21945538
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Reduction of β-amyloid accumulation by reticulon 3 in transgenic mice.

Araki W, Oda A, Motoki K, Hattori K, Itoh M, Yuasa S, Konishi Y, Shin RW, Tamaoka A, Ogino K.

Curr Alzheimer Res. 2013 Feb;10(2):135-42.

PMID:
22742855
[PubMed - indexed for MEDLINE]

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