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Items: 1 to 20 of 80

1.

Too much or too little, how much HDAC activity is good for you?

Matthias P.

Blood. 2013 Mar 14;121(11):1930-1. doi: 10.1182/blood-2013-02-480400.

2.

Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function.

Heideman MR, Wilting RH, Yanover E, Velds A, de Jong J, Kerkhoven RM, Jacobs H, Wessels LF, Dannenberg JH.

Blood. 2013 Mar 14;121(11):2038-50. doi: 10.1182/blood-2012-08-450916. Epub 2013 Jan 17.

3.

A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance.

Santoro F, Botrugno OA, Dal Zuffo R, Pallavicini I, Matthews GM, Cluse L, Barozzi I, Senese S, Fornasari L, Moretti S, Altucci L, Pelicci PG, Chiocca S, Johnstone RW, Minucci S.

Blood. 2013 Apr 25;121(17):3459-68. doi: 10.1182/blood-2012-10-461988. Epub 2013 Feb 25.

4.

Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis.

Winter M, Moser MA, Meunier D, Fischer C, Machat G, Mattes K, Lichtenberger BM, Brunmeir R, Weissmann S, Murko C, Humer C, Meischel T, Brosch G, Matthias P, Sibilia M, Seiser C.

EMBO J. 2013 Dec 11;32(24):3176-91. doi: 10.1038/emboj.2013.243. Epub 2013 Nov 15.

5.

Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells.

LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE.

Dev Cell. 2010 Dec 14;19(6):807-18. doi: 10.1016/j.devcel.2010.10.015. Epub 2010 Nov 18.

6.

Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects.

Marshall GM, Gherardi S, Xu N, Neiron Z, Trahair T, Scarlett CJ, Chang DK, Liu PY, Jankowski K, Iraci N, Haber M, Norris MD, Keating J, Sekyere E, Jonquieres G, Stossi F, Katzenellenbogen BS, Biankin AV, Perini G, Liu T.

Oncogene. 2010 Nov 4;29(44):5957-68. doi: 10.1038/onc.2010.332. Epub 2010 Aug 9.

PMID:
20697349
7.

Histone deacetylase regulation of ATM-mediated DNA damage signaling.

Thurn KT, Thomas S, Raha P, Qureshi I, Munster PN.

Mol Cancer Ther. 2013 Oct;12(10):2078-87. doi: 10.1158/1535-7163.MCT-12-1242. Epub 2013 Aug 12.

8.
9.

Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis.

Wilting RH, Yanover E, Heideman MR, Jacobs H, Horner J, van der Torre J, DePinho RA, Dannenberg JH.

EMBO J. 2010 Aug 4;29(15):2586-97. doi: 10.1038/emboj.2010.136. Epub 2010 Jun 22.

10.

Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression.

Lebrun-Julien F, Suter U.

ASN Neuro. 2015 Jun 30;7(3). pii: 1759091415593066. doi: 10.1177/1759091415593066. Print 2015 May-Jun.

12.

Negative and positive regulation of gene expression by mouse histone deacetylase 1.

Zupkovitz G, Tischler J, Posch M, Sadzak I, Ramsauer K, Egger G, Grausenburger R, Schweifer N, Chiocca S, Decker T, Seiser C.

Mol Cell Biol. 2006 Nov;26(21):7913-28. Epub 2006 Aug 28.

13.

Histone deacetylases specifically down-regulate p53-dependent gene activation.

Juan LJ, Shia WJ, Chen MH, Yang WM, Seto E, Lin YS, Wu CW.

J Biol Chem. 2000 Jul 7;275(27):20436-43.

14.

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells.

Jacob C, Christen CN, Pereira JA, Somandin C, Baggiolini A, Lötscher P, Ozçelik M, Tricaud N, Meijer D, Yamaguchi T, Matthias P, Suter U.

Nat Neurosci. 2011 Apr;14(4):429-36. doi: 10.1038/nn.2762. Epub 2011 Mar 20.

PMID:
21423190
15.

Distinct roles of HDAC1 and HDAC2 in transcription and recombination at the immunoglobulin loci in the chicken B cell line DT40.

Kurosawa K, Lin W, Ohta K.

J Biochem. 2010 Aug;148(2):201-7. doi: 10.1093/jb/mvq054. Epub 2010 May 28.

PMID:
20511365
16.

Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice.

Dovey OM, Foster CT, Conte N, Edwards SA, Edwards JM, Singh R, Vassiliou G, Bradley A, Cowley SM.

Blood. 2013 Feb 21;121(8):1335-44. doi: 10.1182/blood-2012-07-441949. Epub 2013 Jan 3.

17.

Essential Nonredundant Function of the Catalytic Activity of Histone Deacetylase 2 in Mouse Development.

Hagelkruys A, Mattes K, Moos V, Rennmayr M, Ringbauer M, Sawicka A, Seiser C.

Mol Cell Biol. 2015 Nov 23;36(3):462-74. doi: 10.1128/MCB.00639-15.

18.

Opposed regulation of type I IFN-induced STAT3 and ISGF3 transcriptional activities by histone deacetylases (HDACS) 1 and 2.

Icardi L, Lievens S, Mori R, Piessevaux J, De Cauwer L, De Bosscher K, Tavernier J.

FASEB J. 2012 Jan;26(1):240-9. doi: 10.1096/fj.11-191122. Epub 2011 Sep 28.

19.

Hyperoxia arrests alveolar development through suppression of histone deacetylases in neonatal rats.

Zhu L, Li H, Tang J, Zhu J, Zhang Y.

Pediatr Pulmonol. 2012 Mar;47(3):264-74. doi: 10.1002/ppul.21540. Epub 2011 Sep 8.

PMID:
21905265
20.

HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells.

Schüler S, Fritsche P, Diersch S, Arlt A, Schmid RM, Saur D, Schneider G.

Mol Cancer. 2010 Apr 16;9:80. doi: 10.1186/1476-4598-9-80.

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