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Differential expression and tumor necrosis factor-mediated regulation of TNFRSF11b/osteoprotegerin production by human melanomas.

Oliver JL, Alexander MP, Norrod AG, Mullins IM, Mullins DW.

Pigment Cell Melanoma Res. 2013 Jul;26(4):571-9. doi: 10.1111/pcmr.12091. Epub 2013 Apr 11.


Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesis.

Collin-Osdoby P, Rothe L, Anderson F, Nelson M, Maloney W, Osdoby P.

J Biol Chem. 2001 Jun 8;276(23):20659-72. Epub 2001 Mar 23.


RANK-Fc: a therapeutic antagonist for RANK-L in myeloma.

Sordillo EM, Pearse RN.

Cancer. 2003 Feb 1;97(3 Suppl):802-12. Review.


Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing.

Kon T, Cho TJ, Aizawa T, Yamazaki M, Nooh N, Graves D, Gerstenfeld LC, Einhorn TA.

J Bone Miner Res. 2001 Jun;16(6):1004-14.


Functional dissection of osteoprotegerin and its interaction with receptor activator of NF-kappaB ligand.

Schneeweis LA, Willard D, Milla ME.

J Biol Chem. 2005 Dec 16;280(50):41155-64. Epub 2005 Oct 7.


Expression of osteoclast differentiation signals by stromal elements of giant cell tumors.

Atkins GJ, Haynes DR, Graves SE, Evdokiou A, Hay S, Bouralexis S, Findlay DM.

J Bone Miner Res. 2000 Apr;15(4):640-9.


OPG is regulated by beta-catenin and mediates resistance to TRAIL-induced apoptosis in colon cancer.

De Toni EN, Thieme SE, Herbst A, Behrens A, Stieber P, Jung A, Blum H, Göke B, Kolligs FT.

Clin Cancer Res. 2008 Aug 1;14(15):4713-8. doi: 10.1158/1078-0432.CCR-07-5019.


Characterization of synovial cell clones isolated from rheumatoid arthritis patients: possible involvement of TNF-alpha in reduction of osteoprotegerin in synovium.

Zhao B, Takami M, Miyamoto Y, Suzawa T, Yamada A, Mochizuki A, Yasuhara R, Wang X, Inoue T, Namiki O, Sakamoto K, Kamijo R.

Cytokine. 2008 Jan;41(1):61-70. Epub 2007 Dec 20.


Osteoprotegerin overexpression by breast cancer cells enhances orthotopic and osseous tumor growth and contrasts with that delivered therapeutically.

Fisher JL, Thomas-Mudge RJ, Elliott J, Hards DK, Sims NA, Slavin J, Martin TJ, Gillespie MT.

Cancer Res. 2006 Apr 1;66(7):3620-8.


Tumor necrosis factor-alpha promotes the expression of osteoprotegerin in rheumatoid synovial fibroblasts.

Kubota A, Hasegawa K, Suguro T, Koshihara Y.

J Rheumatol. 2004 Mar;31(3):426-35.


Mechanism of bone metastasis: the role of osteoprotegerin and of the host-tissue microenvironment-related survival factors.

Fili S, Karalaki M, Schaller B.

Cancer Lett. 2009 Sep 28;283(1):10-9. doi: 10.1016/j.canlet.2009.01.011. Epub 2009 Feb 6. Review.


Human bone marrow stromal cells protect prostate cancer cells from TRAIL-induced apoptosis.

Nyambo R, Cross N, Lippitt J, Holen I, Bryden G, Hamdy FC, Eaton CL.

J Bone Miner Res. 2004 Oct;19(10):1712-21. Epub 2004 Jul 7.


Osteoprotegerin is expressed in colon carcinoma cells.

Pettersen I, Bakkelund W, Smedsrød B, Sveinbjørnsson B.

Anticancer Res. 2005 Nov-Dec;25(6B):3809-16.


Expression of osteoprotegerin (OPG), TNF related apoptosis inducing ligand (TRAIL), and receptor activator of nuclear factor kappaB ligand (RANKL) in human breast tumours.

Van Poznak C, Cross SS, Saggese M, Hudis C, Panageas KS, Norton L, Coleman RE, Holen I.

J Clin Pathol. 2006 Jan;59(1):56-63.


Cytokine-induced osteoprotegerin expression protects pancreatic beta cells through p38 mitogen-activated protein kinase signalling against cell death.

Schrader J, Rennekamp W, Niebergall U, Schoppet M, Jahr H, Brendel MD, Hörsch D, Hofbauer LC.

Diabetologia. 2007 Jun;50(6):1243-7. Epub 2007 Apr 19.


Osteoprotegerin: a physiological and pharmacological inhibitor of bone resorption.

Kostenuik PJ, Shalhoub V.

Curr Pharm Des. 2001 May;7(8):613-35. Review.


Osteoprotegerin is present on the membrane of osteoclasts isolated from mouse long bones.

Woo KM, Choi Y, Ko SH, Ko JS, Oh KO, Kim KK.

Exp Mol Med. 2002 Nov 30;34(5):347-52.

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