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Results: 1 to 20 of 110

1.

Epigallocatechin gallate promotes p53 accumulation and activity via the inhibition of MDM2-mediated p53 ubiquitination in human lung cancer cells.

Jin L, Li C, Xu Y, Wang L, Liu J, Wang D, Hong C, Jiang Z, Ma Y, Chen Q, Yu F.

Oncol Rep. 2013 May;29(5):1983-90. doi: 10.3892/or.2013.2343. Epub 2013 Mar 12.

PMID:
23483203
[PubMed - indexed for MEDLINE]
2.

Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells.

Hastak K, Gupta S, Ahmad N, Agarwal MK, Agarwal ML, Mukhtar H.

Oncogene. 2003 Jul 31;22(31):4851-9.

PMID:
12894226
[PubMed - indexed for MEDLINE]
3.

Apoptosis of human fibrosarcoma HT-1080 cells by epigallocatechin-3-O-gallate via induction of p53 and caspases as well as suppression of Bcl-2 and phosphorylated nuclear factor-κB.

Lee MH, Han DW, Hyon SH, Park JC.

Apoptosis. 2011 Jan;16(1):75-85. doi: 10.1007/s10495-010-0548-y.

PMID:
20963498
[PubMed - indexed for MEDLINE]
4.

Identification of epigallocatechin-3-gallate in green tea polyphenols as a potent inducer of p53-dependent apoptosis in the human lung cancer cell line A549.

Yamauchi R, Sasaki K, Yoshida K.

Toxicol In Vitro. 2009 Aug;23(5):834-9. doi: 10.1016/j.tiv.2009.04.011. Epub 2009 May 3.

PMID:
19406223
[PubMed - indexed for MEDLINE]
5.

DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer.

Wu DW, Lee MC, Wang J, Chen CY, Cheng YW, Lee H.

Oncogene. 2014 Mar 20;33(12):1515-26. doi: 10.1038/onc.2013.107. Epub 2013 Apr 15.

PMID:
23584477
[PubMed - indexed for MEDLINE]
6.

PKB/Akt activation inhibits p53-mediated HIF1A degradation that is independent of MDM2.

Choy MK, Movassagh M, Bennett MR, Foo RS.

J Cell Physiol. 2010 Mar;222(3):635-9. doi: 10.1002/jcp.21980.

PMID:
19950214
[PubMed - indexed for MEDLINE]
7.

Protein phosphatase-2A is a target of epigallocatechin-3-gallate and modulates p53-Bak apoptotic pathway.

Qin J, Chen HG, Yan Q, Deng M, Liu J, Doerge S, Ma W, Dong Z, Li DW.

Cancer Res. 2008 Jun 1;68(11):4150-62. doi: 10.1158/0008-5472.CAN-08-0839. Erratum in: Cancer Res. 2008 Aug 15;68(16):6859.

PMID:
18519674
[PubMed - indexed for MEDLINE]
Free Article
8.
9.

Knockdown of HURP inhibits the proliferation of hepacellular carcinoma cells via downregulation of gankyrin and accumulation of p53.

Kuo TC, Chang PY, Huang SF, Chou CK, Chao CC.

Biochem Pharmacol. 2012 Mar 15;83(6):758-68. doi: 10.1016/j.bcp.2011.12.034. Epub 2011 Dec 31.

PMID:
22230478
[PubMed - indexed for MEDLINE]
10.

Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-alpha3 binding.

Marchenko ND, Hanel W, Li D, Becker K, Reich N, Moll UM.

Cell Death Differ. 2010 Feb;17(2):255-67. doi: 10.1038/cdd.2009.173. Epub 2009 Nov 20.

PMID:
19927155
[PubMed - indexed for MEDLINE]
Free Article
11.

Retinoblastoma protein modulates gankyrin-MDM2 in regulation of p53 stability and chemosensitivity in cancer cells.

Qiu W, Wu J, Walsh EM, Zhang Y, Chen CY, Fujita J, Xiao ZX.

Oncogene. 2008 Jul 3;27(29):4034-43. doi: 10.1038/onc.2008.43. Epub 2008 Mar 10.

PMID:
18332869
[PubMed - indexed for MEDLINE]
12.

Inhibition of p53 DNA binding function by the MDM2 protein acidic domain.

Cross B, Chen L, Cheng Q, Li B, Yuan ZM, Chen J.

J Biol Chem. 2011 May 6;286(18):16018-29. doi: 10.1074/jbc.M111.228981. Epub 2011 Mar 17.

PMID:
21454483
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Epigallocatechin gallate inhibits growth and epithelial-to-mesenchymal transition in human thyroid carcinoma cell lines.

De Amicis F, Perri A, Vizza D, Russo A, Panno ML, Bonofiglio D, Giordano C, Mauro L, Aquila S, Tramontano D, Andò S.

J Cell Physiol. 2013 Oct;228(10):2054-62. doi: 10.1002/jcp.24372.

PMID:
23553645
[PubMed - indexed for MEDLINE]
14.

Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice.

Jung CR, Lim JH, Choi Y, Kim DG, Kang KJ, Noh SM, Im DS.

J Clin Invest. 2010 Dec;120(12):4493-506. doi: 10.1172/JCI42674. Epub 2010 Nov 8.

PMID:
21060154
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Ablation of either p21 or Bax prevents p53-dependent apoptosis induced by green tea polyphenol epigallocatechin-3-gallate.

Hastak K, Agarwal MK, Mukhtar H, Agarwal ML.

FASEB J. 2005 May;19(7):789-91. Epub 2005 Mar 11.

PMID:
15764647
[PubMed - indexed for MEDLINE]
Free Article
16.

Mdm2 facilitates the association of p53 with the proteasome.

Kulikov R, Letienne J, Kaur M, Grossman SR, Arts J, Blattner C.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10038-43. doi: 10.1073/pnas.0911716107. Epub 2010 May 17.

PMID:
20479273
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor kappaB in cancer cells versus normal cells.

Ahmad N, Gupta S, Mukhtar H.

Arch Biochem Biophys. 2000 Apr 15;376(2):338-46.

PMID:
10775421
[PubMed - indexed for MEDLINE]
18.

Cyclin D1 degradation and p21 induction contribute to growth inhibition of colorectal cancer cells induced by epigallocatechin-3-gallate.

Zhang X, Min KW, Wimalasena J, Baek SJ.

J Cancer Res Clin Oncol. 2012 Dec;138(12):2051-60. doi: 10.1007/s00432-012-1276-1. Epub 2012 Jul 20.

PMID:
22814742
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1α.

Wang H, Bian S, Yang CS.

Carcinogenesis. 2011 Dec;32(12):1881-9. doi: 10.1093/carcin/bgr218. Epub 2011 Sep 28.

PMID:
21965273
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Murine protein serine-threonine kinase 38 activates p53 function through Ser15 phosphorylation.

Seong HA, Ha H.

J Biol Chem. 2012 Jun 15;287(25):20797-810. doi: 10.1074/jbc.M112.347757. Epub 2012 Apr 24.

PMID:
22532570
[PubMed - indexed for MEDLINE]
Free PMC Article

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