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Items: 1 to 20 of 52

1.

Hyperpolarized (13)C-pyruvate magnetic resonance imaging in cancer diagnostics.

Viale A, Reineri F, Dastrù W, Aime S.

Expert Opin Med Diagn. 2012 Jul;6(4):335-45. doi: 10.1517/17530059.2012.687372. Epub 2012 May 9.

PMID:
23480742
2.

Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate.

Nelson SJ, Kurhanewicz J, Vigneron DB, Larson PE, Harzstark AL, Ferrone M, van Criekinge M, Chang JW, Bok R, Park I, Reed G, Carvajal L, Small EJ, Munster P, Weinberg VK, Ardenkjaer-Larsen JH, Chen AP, Hurd RE, Odegardstuen LI, Robb FJ, Tropp J, Murray JA.

Sci Transl Med. 2013 Aug 14;5(198):198ra108. doi: 10.1126/scitranslmed.3006070.

3.

Multimodal assessment of in vivo metabolism with hyperpolarized [1-13C]MR spectroscopy and 18F-FDG PET imaging in hepatocellular carcinoma tumor-bearing rats.

Menzel MI, Farrell EV, Janich MA, Khegai O, Wiesinger F, Nekolla S, Otto AM, Haase A, Schulte RF, Schwaiger M.

J Nucl Med. 2013 Jul;54(7):1113-9. doi: 10.2967/jnumed.112.110825. Epub 2013 Apr 17.

4.

Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells.

Harris T, Eliyahu G, Frydman L, Degani H.

Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18131-6. doi: 10.1073/pnas.0909049106. Epub 2009 Oct 13.

5.

Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis.

Golman K, Zandt RI, Lerche M, Pehrson R, Ardenkjaer-Larsen JH.

Cancer Res. 2006 Nov 15;66(22):10855-60.

6.

Assessment of early diabetic renal changes with hyperpolarized [1-(13) C]pyruvate.

Laustsen C, Østergaard JA, Lauritzen MH, Nørregaard R, Bowen S, Søgaard LV, Flyvbjerg A, Pedersen M, Ardenkjaer-Larsen JH.

Diabetes Metab Res Rev. 2013 Feb;29(2):125-9. doi: 10.1002/dmrr.2370.

PMID:
23166087
7.

Hyperpolarized (13) C-lactate to (13) C-bicarbonate ratio as a biomarker for monitoring the acute response of anti-vascular endothelial growth factor (anti-VEGF) treatment.

Park JM, Spielman DM, Josan S, Jang T, Merchant M, Hurd RE, Mayer D, Recht LD.

NMR Biomed. 2016 May;29(5):650-9. doi: 10.1002/nbm.3509. Epub 2016 Mar 14.

PMID:
26990457
8.

The use of dynamic nuclear polarization (13)C-pyruvate MRS in cancer.

Gutte H, Hansen AE, Johannesen HH, Clemmensen AE, Ardenkjær-Larsen JH, Nielsen CH, Kjær A.

Am J Nucl Med Mol Imaging. 2015 Oct 12;5(5):548-60. eCollection 2015. Review.

9.

Hyperpolarized (13)C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization.

Bohndiek SE, Kettunen MI, Hu DE, Brindle KM.

Cancer Res. 2012 Feb 15;72(4):854-64. doi: 10.1158/0008-5472.CAN-11-2795. Epub 2012 Jan 5.

10.

Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells.

Lodi A, Woods SM, Ronen SM.

NMR Biomed. 2013 Mar;26(3):299-306. doi: 10.1002/nbm.2848. Epub 2012 Sep 3.

11.

13C-MR Spectroscopic Imaging with Hyperpolarized [1-13C]pyruvate Detects Early Response to Radiotherapy in SCC Tumors and HT-29 Tumors.

Saito K, Matsumoto S, Takakusagi Y, Matsuo M, Morris HD, Lizak MJ, Munasinghe JP, Devasahayam N, Subramanian S, Mitchell JB, Krishna MC.

Clin Cancer Res. 2015 Nov 15;21(22):5073-81. doi: 10.1158/1078-0432.CCR-14-1717. Epub 2015 Feb 11.

PMID:
25673698
12.

Probing lactate dehydrogenase activity in tumors by measuring hydrogen/deuterium exchange in hyperpolarized l-[1-(13)C,U-(2)H]lactate.

Kennedy BW, Kettunen MI, Hu DE, Brindle KM.

J Am Chem Soc. 2012 Mar 14;134(10):4969-77. doi: 10.1021/ja300222e. Epub 2012 Mar 1.

13.

Kinetic and perfusion modeling of hyperpolarized (13)C pyruvate and urea in cancer with arbitrary RF flip angles.

Bahrami N, Swisher CL, Von Morze C, Vigneron DB, Larson PE.

Quant Imaging Med Surg. 2014 Feb;4(1):24-32. doi: 10.3978/j.issn.2223-4292.2014.02.02.

14.

Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart.

Schroeder MA, Lau AZ, Chen AP, Gu Y, Nagendran J, Barry J, Hu X, Dyck JR, Tyler DJ, Clarke K, Connelly KA, Wright GA, Cunningham CH.

Eur J Heart Fail. 2013 Feb;15(2):130-40. doi: 10.1093/eurjhf/hfs192. Epub 2012 Dec 19.

15.

Imaging pH with hyperpolarized 13C.

Gallagher FA, Kettunen MI, Brindle KM.

NMR Biomed. 2011 Oct;24(8):1006-15. doi: 10.1002/nbm.1742. Epub 2011 Aug 3. Review.

PMID:
21812047
16.

Imaging tumour cell metabolism using hyperpolarized 13C magnetic resonance spectroscopy.

Witney TH, Brindle KM.

Biochem Soc Trans. 2010 Oct;38(5):1220-4. doi: 10.1042/BST0381220.

PMID:
20863288
17.

Field dependence of T1 for hyperpolarized [1-13C]pyruvate.

Chattergoon N, Martínez-Santiesteban F, Handler WB, Ardenkjaer-Larsen JH, Scholl TJ.

Contrast Media Mol Imaging. 2013 Jan-Feb;8(1):57-62. doi: 10.1002/cmmi.1494.

PMID:
23109393
18.

In vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model.

Lee P, Leong W, Tan T, Lim M, Han W, Radda GK.

Hepatology. 2013 Feb;57(2):515-24. doi: 10.1002/hep.26028. Epub 2013 Jan 10.

PMID:
22911492
19.

Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging.

Park I, Bok R, Ozawa T, Phillips JJ, James CD, Vigneron DB, Ronen SM, Nelson SJ.

J Magn Reson Imaging. 2011 Jun;33(6):1284-90. doi: 10.1002/jmri.22563.

PMID:
21590996
20.

DNP-Hyperpolarized C Magnetic Resonance Metabolic Imaging for Cancer Applications.

Nelson SJ, Vigneron D, Kurhanewicz J, Chen A, Bok R, Hurd R.

Appl Magn Reson. 2008;34(3-4):533-544.

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