Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 87

1.

Ku70 functions in addition to nonhomologous end joining in pancreatic β-cells: a connection to β-catenin regulation.

Tavana O, Puebla-Osorio N, Kim J, Sang M, Jang S, Zhu C.

Diabetes. 2013 Jul;62(7):2429-38. doi: 10.2337/db12-1218. Epub 2013 Mar 8.

PMID:
23474484
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A novel Ku70 function in colorectal homeostasis separate from nonhomologous end joining.

Puebla-Osorio N, Kim J, Ojeda S, Zhang H, Tavana O, Li S, Wang Y, Ma Q, Schluns KS, Zhu C.

Oncogene. 2014 May 22;33(21):2748-57. doi: 10.1038/onc.2013.234. Epub 2013 Jun 10.

PMID:
23752193
[PubMed - indexed for MEDLINE]
3.

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4.

Mari PO, Florea BI, Persengiev SP, Verkaik NS, Brüggenwirth HT, Modesti M, Giglia-Mari G, Bezstarosti K, Demmers JA, Luider TM, Houtsmuller AB, van Gent DC.

Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18597-602. Epub 2006 Nov 21.

PMID:
17124166
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Mycobacterium tuberculosis Ku can bind to nuclear DNA damage and sensitize mammalian cells to bleomycin sulfate.

Castore R, Hughes C, Debeaux A, Sun J, Zeng C, Wang SY, Tatchell K, Shi R, Lee KJ, Chen DJ, Harrison L.

Mutagenesis. 2011 Nov;26(6):795-803. doi: 10.1093/mutage/ger049. Epub 2011 Aug 2.

PMID:
21811007
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction.

Oh S, Wang Y, Zimbric J, Hendrickson EA.

Nucleic Acids Res. 2013 Feb 1;41(3):1734-49. doi: 10.1093/nar/gks1326. Epub 2012 Dec 28.

PMID:
23275564
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Absence of p53-dependent apoptosis combined with nonhomologous end-joining deficiency leads to a severe diabetic phenotype in mice.

Tavana O, Puebla-Osorio N, Sang M, Zhu C.

Diabetes. 2010 Jan;59(1):135-42. doi: 10.2337/db09-0792. Epub 2009 Oct 15.

PMID:
19833883
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling.

Idogawa M, Masutani M, Shitashige M, Honda K, Tokino T, Shinomura Y, Imai K, Hirohashi S, Yamada T.

Cancer Res. 2007 Feb 1;67(3):911-8.

PMID:
17283121
[PubMed - indexed for MEDLINE]
Free Article
8.

Major vault protein may affect nonhomologous end-joining repair and apoptosis through Ku70/80 and bax downregulation in cervical carcinoma tumors.

Lloret M, Lara PC, Bordón E, Fontes F, Rey A, Pinar B, Falcón O.

Int J Radiat Oncol Biol Phys. 2009 Mar 15;73(4):976-9. doi: 10.1016/j.ijrobp.2008.11.013.

PMID:
19251084
[PubMed - indexed for MEDLINE]
9.

Ku80-deleted cells are defective at base excision repair.

Li H, Marple T, Hasty P.

Mutat Res. 2013 May-Jun;745-746:16-25. doi: 10.1016/j.mrfmmm.2013.03.010. Epub 2013 Apr 6.

PMID:
23567907
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescence.

Yao H, Sundar IK, Gorbunova V, Rahman I.

PLoS One. 2013 Nov 11;8(11):e80007. doi: 10.1371/journal.pone.0080007. eCollection 2013.

PMID:
24244594
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts.

Gassman NR, Stefanick DF, Kedar PS, Horton JK, Wilson SH.

PLoS One. 2012;7(11):e49301. doi: 10.1371/journal.pone.0049301. Epub 2012 Nov 7.

PMID:
23145148
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair.

Adachi N, Ishino T, Ishii Y, Takeda S, Koyama H.

Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12109-13.

PMID:
11593023
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks.

Drouet J, Delteil C, Lefrançois J, Concannon P, Salles B, Calsou P.

J Biol Chem. 2005 Feb 25;280(8):7060-9. Epub 2004 Oct 31.

PMID:
15520013
[PubMed - indexed for MEDLINE]
Free Article
14.

Repairing DNA damage by XRCC6/KU70 reverses TLR4-deficiency-worsened HCC development via restoring senescence and autophagic flux.

Wang Z, Lin H, Hua F, Hu ZW.

Autophagy. 2013 Jun 1;9(6):925-7. doi: 10.4161/auto.24229. Epub 2013 Mar 21.

PMID:
23518600
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells.

Wang H, Zeng ZC, Perrault AR, Cheng X, Qin W, Iliakis G.

Nucleic Acids Res. 2001 Apr 15;29(8):1653-60.

PMID:
11292837
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Inhibition of Ku70 acetylation by INHAT subunit SET/TAF-Iβ regulates Ku70-mediated DNA damage response.

Kim KB, Kim DW, Park JW, Jeon YJ, Kim D, Rhee S, Chae JI, Seo SB.

Cell Mol Life Sci. 2014 Jul;71(14):2731-45. doi: 10.1007/s00018-013-1525-8. Epub 2013 Dec 5.

PMID:
24305947
[PubMed - indexed for MEDLINE]
17.

Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: a multigenic study on cancer susceptibility.

Fu YP, Yu JC, Cheng TC, Lou MA, Hsu GC, Wu CY, Chen ST, Wu HS, Wu PE, Shen CY.

Cancer Res. 2003 May 15;63(10):2440-6.

PMID:
12750264
[PubMed - indexed for MEDLINE]
Free Article
18.

Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice.

Teoh NC, Dan YY, Swisshelm K, Lehman S, Wright JH, Haque J, Gu Y, Fausto N.

Hepatology. 2008 Jun;47(6):2078-88. doi: 10.1002/hep.22194.

PMID:
18506893
[PubMed - indexed for MEDLINE]
19.

Biochemical evidence for Ku-independent backup pathways of NHEJ.

Wang H, Perrault AR, Takeda Y, Qin W, Wang H, Iliakis G.

Nucleic Acids Res. 2003 Sep 15;31(18):5377-88.

PMID:
12954774
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Removal of shelterin reveals the telomere end-protection problem.

Sfeir A, de Lange T.

Science. 2012 May 4;336(6081):593-7. doi: 10.1126/science.1218498.

PMID:
22556254
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk