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Items: 1 to 20 of 135

1.

Structure of EvaA: a paradigm for sugar 2,3-dehydratases.

Kubiak RL, Thoden JB, Holden HM.

Biochemistry. 2013 Mar 26;52(12):2078-88. doi: 10.1021/bi400176n. Epub 2013 Mar 12.

PMID:
23473392
2.

The crystal structure of dTDP-D-Glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium, the second enzyme in the dTDP-l-rhamnose pathway.

Allard ST, Giraud MF, Whitfield C, Graninger M, Messner P, Naismith JH.

J Mol Biol. 2001 Mar 16;307(1):283-95.

PMID:
11243820
3.

Structural and kinetic analysis of Escherichia coli GDP-mannose 4,6 dehydratase provides insights into the enzyme's catalytic mechanism and regulation by GDP-fucose.

Somoza JR, Menon S, Schmidt H, Joseph-McCarthy D, Dessen A, Stahl ML, Somers WS, Sullivan FX.

Structure. 2000 Feb 15;8(2):123-35.

4.

The structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa.

Kimber MS, Martin F, Lu Y, Houston S, Vedadi M, Dharamsi A, Fiebig KM, Schmid M, Rock CO.

J Biol Chem. 2004 Dec 10;279(50):52593-602. Epub 2004 Sep 14.

5.

Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus.

de la Peña AH, Suarez A, Duong-Ly KC, Schoeffield AJ, Pizarro-Dupuy MA, Zarr M, Pineiro SA, Amzel LM, Gabelli SB.

PLoS One. 2015 Nov 2;10(11):e0141716. doi: 10.1371/journal.pone.0141716. eCollection 2015.

6.

Toward a structural understanding of the dehydratase mechanism.

Allard ST, Beis K, Giraud MF, Hegeman AD, Gross JW, Wilmouth RC, Whitfield C, Graninger M, Messner P, Allen AG, Maskell DJ, Naismith JH.

Structure. 2002 Jan;10(1):81-92.

7.
8.

Three-dimensional structure of a sugar N-formyltransferase from Francisella tularensis.

Zimmer AL, Thoden JB, Holden HM.

Protein Sci. 2014 Mar;23(3):273-83. doi: 10.1002/pro.2409. Epub 2014 Jan 22.

9.

GDP-4-keto-6-deoxy-D-mannose 3-dehydratase, accommodating a sugar substrate in the active site.

Cook PD, Holden HM.

J Biol Chem. 2008 Feb 15;283(7):4295-303. Epub 2007 Nov 28.

10.

Two site-directed mutations are required for the conversion of a sugar dehydratase into an aminotransferase.

Cook PD, Kubiak RL, Toomey DP, Holden HM.

Biochemistry. 2009 Jun 16;48(23):5246-53. doi: 10.1021/bi9005545.

11.

GDP-perosamine synthase: structural analysis and production of a novel trideoxysugar.

Cook PD, Holden HM.

Biochemistry. 2008 Mar 4;47(9):2833-40. doi: 10.1021/bi702430d. Epub 2008 Feb 5.

PMID:
18247575
12.

Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.

Brouns SJ, Barends TR, Worm P, Akerboom J, Turnbull AP, Salmon L, van der Oost J.

J Mol Biol. 2008 May 30;379(2):357-71. doi: 10.1016/j.jmb.2008.03.064. Epub 2008 Apr 8.

PMID:
18448118
13.

Structural studies of AntD: an N-Acyltransferase involved in the biosynthesis of D-Anthrose.

Kubiak RL, Holden HM.

Biochemistry. 2012 Jan 31;51(4):867-78. doi: 10.1021/bi201650c. Epub 2012 Jan 17.

PMID:
22220494
14.

Molecular architecture of TylM1 from Streptomyces fradiae: an N,N-dimethyltransferase involved in the production of dTDP-D-mycaminose.

Carney AE, Holden HM.

Biochemistry. 2011 Feb 8;50(5):780-7. doi: 10.1021/bi101733y. Epub 2011 Jan 14.

15.
16.

The x-ray structure of dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase.

Davis ML, Thoden JB, Holden HM.

J Biol Chem. 2007 Jun 29;282(26):19227-36. Epub 2007 Apr 25.

17.

Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase.

Cook PD, Carney AE, Holden HM.

Biochemistry. 2008 Oct 7;47(40):10685-93. doi: 10.1021/bi801309q. Epub 2008 Sep 17.

PMID:
18795799
18.

Structure of CDP-D-glucose 4,6-dehydratase from Salmonella typhi complexed with CDP-D-xylose.

Koropatkin NM, Holden HM.

Acta Crystallogr D Biol Crystallogr. 2005 Apr;61(Pt 4):365-73. Epub 2005 Mar 24.

PMID:
15805590
20.
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