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Results: 1 to 20 of 114

1.

Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs.

Villanueva CJ, Vergnes L, Wang J, Drew BG, Hong C, Tu Y, Hu Y, Peng X, Xu F, Saez E, Wroblewski K, Hevener AL, Reue K, Fong LG, Young SG, Tontonoz P.

Cell Metab. 2013 Mar 5;17(3):423-35. doi: 10.1016/j.cmet.2013.01.016.

PMID:
23473036
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Peroxisome proliferator-activated receptor α (PPARα) induces PPARγ coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16.

Hondares E, Rosell M, Díaz-Delfín J, Olmos Y, Monsalve M, Iglesias R, Villarroya F, Giralt M.

J Biol Chem. 2011 Dec 16;286(50):43112-22. doi: 10.1074/jbc.M111.252775. Epub 2011 Oct 27.

PMID:
22033933
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.

Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J, Cohen P, Cinti S, Spiegelman BM.

J Clin Invest. 2011 Jan;121(1):96-105. doi: 10.1172/JCI44271. Epub 2010 Dec 1.

PMID:
21123942
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Role of PRDM16 in the activation of brown fat programming. Relevance to the development of obesity.

Becerril S, Gómez-Ambrosi J, Martín M, Moncada R, Sesma P, Burrell MA, Frühbeck G.

Histol Histopathol. 2013 Nov;28(11):1411-25. Epub 2013 Jun 17. Review.

PMID:
23771475
[PubMed - indexed for MEDLINE]
5.

PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein.

Ohno H, Shinoda K, Spiegelman BM, Kajimura S.

Cell Metab. 2012 Mar 7;15(3):395-404. doi: 10.1016/j.cmet.2012.01.019.

PMID:
22405074
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.

Kajimura S, Seale P, Tomaru T, Erdjument-Bromage H, Cooper MP, Ruas JL, Chin S, Tempst P, Lazar MA, Spiegelman BM.

Genes Dev. 2008 May 15;22(10):1397-409. doi: 10.1101/gad.1666108.

PMID:
18483224
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Decreased brown adipocyte recruitment and thermogenic capacity in mice with impaired peroxisome proliferator-activated receptor (P465L PPARgamma) function.

Gray SL, Dalla Nora E, Backlund EC, Manieri M, Virtue S, Noland RC, O'Rahilly S, Cortright RN, Cinti S, Cannon B, Vidal-Puig A.

Endocrinology. 2006 Dec;147(12):5708-14. Epub 2006 Sep 15.

PMID:
16980437
[PubMed - indexed for MEDLINE]
8.

miR-133a regulates adipocyte browning in vivo.

Liu W, Bi P, Shan T, Yang X, Yin H, Wang YX, Liu N, Rudnicki MA, Kuang S.

PLoS Genet. 2013;9(7):e1003626. doi: 10.1371/journal.pgen.1003626. Epub 2013 Jul 11.

PMID:
23874225
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis.

Cao L, Choi EY, Liu X, Martin A, Wang C, Xu X, During MJ.

Cell Metab. 2011 Sep 7;14(3):324-38. doi: 10.1016/j.cmet.2011.06.020.

PMID:
21907139
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Transcriptional control of brown fat determination by PRDM16.

Seale P, Kajimura S, Yang W, Chin S, Rohas LM, Uldry M, Tavernier G, Langin D, Spiegelman BM.

Cell Metab. 2007 Jul;6(1):38-54.

PMID:
17618855
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Human BAT possesses molecular signatures that resemble beige/brite cells.

Sharp LZ, Shinoda K, Ohno H, Scheel DW, Tomoda E, Ruiz L, Hu H, Wang L, Pavlova Z, Gilsanz V, Kajimura S.

PLoS One. 2012;7(11):e49452. doi: 10.1371/journal.pone.0049452. Epub 2012 Nov 16.

PMID:
23166672
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.

Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR.

Nature. 2008 Aug 21;454(7207):1000-4. doi: 10.1038/nature07221.

PMID:
18719589
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Dynamic regulation of genes involved in mitochondrial DNA replication and transcription during mouse brown fat cell differentiation and recruitment.

Murholm M, Dixen K, Qvortrup K, Hansen LH, Amri EZ, Madsen L, Barbatelli G, Quistorff B, Hansen JB.

PLoS One. 2009 Dec 24;4(12):e8458. doi: 10.1371/journal.pone.0008458.

PMID:
20107496
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ.

Qiang L, Wang L, Kon N, Zhao W, Lee S, Zhang Y, Rosenbaum M, Zhao Y, Gu W, Farmer SR, Accili D.

Cell. 2012 Aug 3;150(3):620-32. doi: 10.1016/j.cell.2012.06.027.

PMID:
22863012
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex.

Ohno H, Shinoda K, Ohyama K, Sharp LZ, Kajimura S.

Nature. 2013 Dec 5;504(7478):163-7. doi: 10.1038/nature12652. Epub 2013 Nov 6.

PMID:
24196706
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

PRDM16 controls a brown fat/skeletal muscle switch.

Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, Scimè A, Devarakonda S, Conroe HM, Erdjument-Bromage H, Tempst P, Rudnicki MA, Beier DR, Spiegelman BM.

Nature. 2008 Aug 21;454(7207):961-7. doi: 10.1038/nature07182.

PMID:
18719582
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes.

Petrovic N, Walden TB, Shabalina IG, Timmons JA, Cannon B, Nedergaard J.

J Biol Chem. 2010 Mar 5;285(10):7153-64. doi: 10.1074/jbc.M109.053942. Epub 2009 Dec 22.

PMID:
20028987
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis.

Fujimoto Y, Nakagawa Y, Satoh A, Okuda K, Shingyouchi A, Naka A, Matsuzaka T, Iwasaki H, Kobayashi K, Yahagi N, Shimada M, Yatoh S, Suzuki H, Yogosawa S, Izumi T, Sone H, Urayama O, Yamada N, Shimano H.

Endocrinology. 2013 Oct;154(10):3577-88. doi: 10.1210/en.2013-1203. Epub 2013 Jul 24.

PMID:
23885019
[PubMed - indexed for MEDLINE]
19.

Double Myod and Igf2 inactivation promotes brown adipose tissue development by increasing Prdm16 expression.

Borensztein M, Viengchareun S, Montarras D, Journot L, Binart N, Lombès M, Dandolo L.

FASEB J. 2012 Nov;26(11):4584-91. doi: 10.1096/fj.12-208496. Epub 2012 Aug 2.

PMID:
22859371
[PubMed - indexed for MEDLINE]
Free Article
20.

Peroxisome proliferator-activated receptors-α and -γ, and cAMP-mediated pathways, control retinol-binding protein-4 gene expression in brown adipose tissue.

Rosell M, Hondares E, Iwamoto S, Gonzalez FJ, Wabitsch M, Staels B, Olmos Y, Monsalve M, Giralt M, Iglesias R, Villarroya F.

Endocrinology. 2012 Mar;153(3):1162-73. doi: 10.1210/en.2011-1367. Epub 2012 Jan 17.

PMID:
22253419
[PubMed - indexed for MEDLINE]

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