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Results: 1 to 20 of 124

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1.

Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity.

Hosokawa H, Tanaka T, Suzuki Y, Iwamura C, Ohkubo S, Endoh K, Kato M, Endo Y, Onodera A, Tumes DJ, Kanai A, Sugano S, Nakayama T.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4691-6. doi: 10.1073/pnas.1220865110. Epub 2013 Mar 7.

2.

Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression.

Hosokawa H, Tanaka T, Kato M, Shinoda K, Tohyama H, Hanazawa A, Tamaki Y, Hirahara K, Yagi R, Sakikawa I, Morita A, Nagira M, Poyurovsky MV, Suzuki Y, Motohashi S, Nakayama T.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18626-31. doi: 10.1073/pnas.1311100110. Epub 2013 Oct 28.

3.

Functional involvement of dual specificity phosphatase 16 (DUSP16), a c-Jun N-terminal kinase-specific phosphatase, in the regulation of T helper cell differentiation.

Musikacharoen T, Bandow K, Kakimoto K, Kusuyama J, Onishi T, Yoshikai Y, Matsuguchi T.

J Biol Chem. 2011 Jul 15;286(28):24896-905. doi: 10.1074/jbc.M111.245019. Epub 2011 May 25.

4.

T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription.

Usui T, Preiss JC, Kanno Y, Yao ZJ, Bream JH, O'Shea JJ, Strober W.

J Exp Med. 2006 Mar 20;203(3):755-66. Epub 2006 Mar 6. Erratum in: J Exp Med. 2006 Apr 17;203(4):1129.

5.

Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function.

Sawant DV, Sehra S, Nguyen ET, Jadhav R, Englert K, Shinnakasu R, Hangoc G, Broxmeyer HE, Nakayama T, Perumal NB, Kaplan MH, Dent AL.

J Immunol. 2012 Nov 15;189(10):4759-69. doi: 10.4049/jimmunol.1201794. Epub 2012 Oct 10.

6.

A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation.

Das J, Chen CH, Yang L, Cohn L, Ray P, Ray A.

Nat Immunol. 2001 Jan;2(1):45-50.

PMID:
11135577
7.

Transcription factors T-bet and GATA-3 regulate development of airway remodeling.

Kiwamoto T, Ishii Y, Morishima Y, Yoh K, Maeda A, Ishizaki K, Iizuka T, Hegab AE, Matsuno Y, Homma S, Nomura A, Sakamoto T, Takahashi S, Sekizawa K.

Am J Respir Crit Care Med. 2006 Jul 15;174(2):142-51. Epub 2006 Apr 13.

PMID:
16614350
8.

The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma.

Yagi R, Junttila IS, Wei G, Urban JF Jr, Zhao K, Paul WE, Zhu J.

Immunity. 2010 Apr 23;32(4):507-17. doi: 10.1016/j.immuni.2010.04.004. Epub 2010 Apr 15.

9.

[Imbalanced T cell-specific transcription factors T-bet and GATA-3 contributes to type 2 T helper cell polarization in asthmatic patients].

Liu CT, Wang G, Luo FM, Wang ZL, Liu R, Wang CL.

Zhonghua Jie He He Hu Xi Za Zhi. 2004 Jun;27(6):398-402. Chinese.

PMID:
15256090
10.

STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells.

Onodera A, Yamashita M, Endo Y, Kuwahara M, Tofukuji S, Hosokawa H, Kanai A, Suzuki Y, Nakayama T.

J Exp Med. 2010 Oct 25;207(11):2493-506. doi: 10.1084/jem.20100760. Epub 2010 Oct 18.

11.

Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T cell compartment in vivo.

Nawijn MC, Dingjan GM, Ferreira R, Lambrecht BN, Karis A, Grosveld F, Savelkoul H, Hendriks RW.

J Immunol. 2001 Jul 15;167(2):724-32.

12.

Lck mediates Th2 differentiation through effects on T-bet and GATA-3.

Kemp KL, Levin SD, Bryce PJ, Stein PL.

J Immunol. 2010 Apr 15;184(8):4178-84. doi: 10.4049/jimmunol.0901282. Epub 2010 Mar 17.

13.

D-pinitol regulates Th1/Th2 balance via suppressing Th2 immune response in ovalbumin-induced asthma.

Lee JS, Lee CM, Jeong YI, Jung ID, Kim BH, Seong EY, Kim JI, Choi IW, Chung HY, Park YM.

FEBS Lett. 2007 Jan 9;581(1):57-64. Epub 2006 Dec 11.

14.

T-bet/GATA-3 ratio as a measure of the Th1/Th2 cytokine profile in mixed cell populations: predominant role of GATA-3.

Chakir H, Wang H, Lefebvre DE, Webb J, Scott FW.

J Immunol Methods. 2003 Jul;278(1-2):157-69.

PMID:
12957404
15.

Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions.

Hegazy AN, Peine M, Helmstetter C, Panse I, Fröhlich A, Bergthaler A, Flatz L, Pinschewer DD, Radbruch A, Löhning M.

Immunity. 2010 Jan 29;32(1):116-28. doi: 10.1016/j.immuni.2009.12.004. Epub 2010 Jan 14.

16.

Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus.

Yamashita M, Ukai-Tadenuma M, Kimura M, Omori M, Inami M, Taniguchi M, Nakayama T.

J Biol Chem. 2002 Nov 1;277(44):42399-408. Epub 2002 Aug 29.

17.

Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function.

Morales-Tirado V, Sojka DK, Katzman SD, Lazarski CA, Finkelman FD, Urban JF, Fowell DJ.

Blood. 2010 Apr 29;115(17):3498-507. doi: 10.1182/blood-2009-07-235754. Epub 2009 Dec 23.

18.

Quercetin regulates Th1/Th2 balance in a murine model of asthma.

Park HJ, Lee CM, Jung ID, Lee JS, Jeong YI, Chang JH, Chun SH, Kim MJ, Choi IW, Ahn SC, Shin YK, Yeom SR, Park YM.

Int Immunopharmacol. 2009 Mar;9(3):261-7. doi: 10.1016/j.intimp.2008.10.021. Epub 2008 Dec 4.

PMID:
19061976
19.

IL4 blockade of inducible regulatory T cell differentiation: the role of Th2 cells, Gata3 and PU.1.

Hadjur S, Bruno L, Hertweck A, Cobb BS, Taylor B, Fisher AG, Merkenschlager M.

Immunol Lett. 2009 Jan 29;122(1):37-43. doi: 10.1016/j.imlet.2008.11.001. Epub 2008 Nov 29.

PMID:
19046990
20.

Elevated interferon regulatory factor 4 levels in patients with allergic asthma.

Chen X, Gao YD, Yang J.

J Asthma. 2012 Jun;49(5):441-9. doi: 10.3109/02770903.2012.674998. Epub 2012 Apr 19.

PMID:
22515488
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