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Items: 1 to 20 of 101

1.

Transforming growth factor beta receptor 2 (TGFBR2) changes sialylation in the microsatellite unstable (MSI) Colorectal cancer cell line HCT116.

Lee J, Ballikaya S, Schönig K, Ball CR, Glimm H, Kopitz J, Gebert J.

PLoS One. 2013;8(2):e57074. doi: 10.1371/journal.pone.0057074. Epub 2013 Feb 27.

2.

Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2.

de Miranda NF, van Dinther M, van den Akker BE, van Wezel T, ten Dijke P, Morreau H.

Gastroenterology. 2015 Jun;148(7):1427-37.e8. doi: 10.1053/j.gastro.2015.02.052. Epub 2015 Feb 28.

PMID:
25736321
3.

Mutational inactivation of TGFBR2 in microsatellite unstable colon cancer arises from the cooperation of genomic instability and the clonal outgrowth of transforming growth factor beta resistant cells.

Biswas S, Trobridge P, Romero-Gallo J, Billheimer D, Myeroff LL, Willson JK, Markowitz SD, Grady WM.

Genes Chromosomes Cancer. 2008 Feb;47(2):95-106.

PMID:
17985359
4.

Compensation of loss of protein function in microsatellite-unstable colon cancer cells (HCT116): a gene-dependent effect on the cell surface glycan profile.

Patsos G, André S, Roeckel N, Gromes R, Gebert J, Kopitz J, Gabius HJ.

Glycobiology. 2009 Jul;19(7):726-34. doi: 10.1093/glycob/cwp040. Epub 2009 Mar 17.

5.

TGFBR2 and BAX mononucleotide tract mutations, microsatellite instability, and prognosis in 1072 colorectal cancers.

Shima K, Morikawa T, Yamauchi M, Kuchiba A, Imamura Y, Liao X, Meyerhardt JA, Fuchs CS, Ogino S.

PLoS One. 2011;6(9):e25062. doi: 10.1371/journal.pone.0025062. Epub 2011 Sep 20.

6.

Significance of mutations in TGFBR2 and BAX in neoplastic progression and patient outcome in sporadic colorectal tumors with high-frequency microsatellite instability.

Fernández-Peralta AM, Nejda N, Oliart S, Medina V, Azcoita MM, González-Aguilera JJ.

Cancer Genet Cytogenet. 2005 Feb;157(1):18-24.

PMID:
15676142
7.

Mutations in TGFbeta-RII and BAX mediate tumor progression in the later stages of colorectal cancer with microsatellite instability.

Yashiro M, Hirakawa K, Boland CR.

BMC Cancer. 2010 Jun 18;10:303. doi: 10.1186/1471-2407-10-303.

8.

TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.

Ogino S, Kawasaki T, Ogawa A, Kirkner GJ, Loda M, Fuchs CS.

Hum Pathol. 2007 Apr;38(4):614-20. Epub 2007 Jan 31.

PMID:
17270239
9.

Reconstitution of TGFBR2 in HCT116 colorectal cancer cells causes increased LFNG expression and enhanced N-acetyl-d-glucosamine incorporation into Notch1.

Lee J, Katzenmaier EM, Kopitz J, Gebert J.

Cell Signal. 2016 Aug;28(8):1105-13. doi: 10.1016/j.cellsig.2016.04.012. Epub 2016 May 5.

PMID:
27156840
10.

Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers.

Jung B, Doctolero RT, Tajima A, Nguyen AK, Keku T, Sandler RS, Carethers JM.

Gastroenterology. 2004 Mar;126(3):654-9.

PMID:
14988818
11.

Reconstitution of TGFBR2-Mediated Signaling Causes Upregulation of GDF-15 in HCT116 Colorectal Cancer Cells.

Lee J, Fricke F, Warnken U, Schnölzer M, Kopitz J, Gebert J.

PLoS One. 2015 Jun 26;10(6):e0131506. doi: 10.1371/journal.pone.0131506. eCollection 2015.

12.

Epithelial to mesenchymal transition is impaired in colon cancer cells with microsatellite instability.

Pino MS, Kikuchi H, Zeng M, Herraiz MT, Sperduti I, Berger D, Park DY, Iafrate AJ, Zukerberg LR, Chung DC.

Gastroenterology. 2010 Apr;138(4):1406-17. doi: 10.1053/j.gastro.2009.12.010. Epub 2009 Dec 21.

13.
14.

Proliferation and Cdk4 expression in microsatellite unstable colon cancers with TGFBR2 mutations.

Grady WM, Willis JE, Trobridge P, Romero-Gallo J, Munoz N, Olechnowicz J, Ferguson K, Gautam S, Markowitz SD.

Int J Cancer. 2006 Feb 1;118(3):600-8.

15.
17.

Two types of sporadic multiple colorectal cancers with and without HNPCC-like genetic instability.

Komura K, Masuda H, Esumi M.

Hepatogastroenterology. 1999 Nov-Dec;46(30):3115-20.

PMID:
10626171
18.

Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers.

Hempen PM, Zhang L, Bansal RK, Iacobuzio-Donahue CA, Murphy KM, Maitra A, Vogelstein B, Whitehead RH, Markowitz SD, Willson JK, Yeo CJ, Hruban RH, Kern SE.

Cancer Res. 2003 Mar 1;63(5):994-9.

19.
20.

Mesalazine reduces mutations in transforming growth factor beta receptor II and activin type II receptor by improvement of replication fidelity in mononucleotide repeats.

Campregher C, Honeder C, Chung H, Carethers JM, Gasche C.

Clin Cancer Res. 2010 Mar 15;16(6):1950-6. doi: 10.1158/1078-0432.CCR-09-2854. Epub 2010 Mar 2.

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