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Results: 1 to 20 of 106

1.

Exacerbated autoimmunity in the absence of TLR9 in MRL.Fas(lpr) mice depends on Ifnar1.

Nickerson KM, Cullen JL, Kashgarian M, Shlomchik MJ.

J Immunol. 2013 Apr 15;190(8):3889-94. doi: 10.4049/jimmunol.1203525. Epub 2013 Mar 6.

PMID:
23467932
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus.

Nickerson KM, Christensen SR, Shupe J, Kashgarian M, Kim D, Elkon K, Shlomchik MJ.

J Immunol. 2010 Feb 15;184(4):1840-8. doi: 10.4049/jimmunol.0902592. Epub 2010 Jan 20.

PMID:
20089701
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Type I IFN protects against murine lupus.

Hron JD, Peng SL.

J Immunol. 2004 Aug 1;173(3):2134-42.

PMID:
15265950
[PubMed - indexed for MEDLINE]
Free Article
4.

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

Christensen SR, Shupe J, Nickerson K, Kashgarian M, Flavell RA, Shlomchik MJ.

Immunity. 2006 Sep;25(3):417-28.

PMID:
16973389
[PubMed - indexed for MEDLINE]
Free Article
5.

IL-10 regulates murine lupus.

Yin Z, Bahtiyar G, Zhang N, Liu L, Zhu P, Robert ME, McNiff J, Madaio MP, Craft J.

J Immunol. 2002 Aug 15;169(4):2148-55.

PMID:
12165544
[PubMed - indexed for MEDLINE]
Free Article
6.

IFN-gamma receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice.

Schwarting A, Wada T, Kinoshita K, Tesch G, Kelley VR.

J Immunol. 1998 Jul 1;161(1):494-503.

PMID:
9647261
[PubMed - indexed for MEDLINE]
Free Article
7.

Programmed death ligand 1 regulates a critical checkpoint for autoimmune myocarditis and pneumonitis in MRL mice.

Lucas JA, Menke J, Rabacal WA, Schoen FJ, Sharpe AH, Kelley VR.

J Immunol. 2008 Aug 15;181(4):2513-21.

PMID:
18684942
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Genetic determinants of autoimmune disease and coronary vasculitis in the MRL-lpr/lpr mouse model of systemic lupus erythematosus.

Gu L, Weinreb A, Wang XP, Zack DJ, Qiao JH, Weisbart R, Lusis AJ.

J Immunol. 1998 Dec 15;161(12):6999-7006.

PMID:
9862736
[PubMed - indexed for MEDLINE]
Free Article
9.

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9.

Guiducci C, Tripodo C, Gong M, Sangaletti S, Colombo MP, Coffman RL, Barrat FJ.

J Exp Med. 2010 Dec 20;207(13):2931-42. doi: 10.1084/jem.20101048. Epub 2010 Nov 29.

PMID:
21115693
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

FcgammaRIIB deficiency with Fas mutation is sufficient for the development of systemic autoimmune disease.

Yajima K, Nakamura A, Sugahara A, Takai T.

Eur J Immunol. 2003 Apr;33(4):1020-9.

PMID:
12672068
[PubMed - indexed for MEDLINE]
11.

Deficiency of type I IFN receptor in lupus-prone New Zealand mixed 2328 mice decreases dendritic cell numbers and activation and protects from disease.

Agrawal H, Jacob N, Carreras E, Bajana S, Putterman C, Turner S, Neas B, Mathian A, Koss MN, Stohl W, Kovats S, Jacob CO.

J Immunol. 2009 Nov 1;183(9):6021-9. doi: 10.4049/jimmunol.0803872. Epub 2009 Oct 7.

PMID:
19812195
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

An essential role for IFN-alpha in the overexpression of Fas ligand on MRL/lpr lymphocytes and on their spontaneous Fas-mediated cytotoxic potential.

Hadj-Slimane R, Chelbi-Alix MK, Tovey MG, Bobé P.

J Interferon Cytokine Res. 2004 Dec;24(12):717-28.

PMID:
15684739
[PubMed - indexed for MEDLINE]
13.

Terminal deoxynucleotidyl transferase deficiency decreases autoimmune disease in MRL-Fas(lpr) mice.

Feeney AJ, Lawson BR, Kono DH, Theofilopoulos AN.

J Immunol. 2001 Sep 15;167(6):3486-93.

PMID:
11544342
[PubMed - indexed for MEDLINE]
Free Article
14.

Clear suppression of Th1 responses but marginal amelioration of autoimmune manifestations by IL-12p40 transgene in MRL-FAS(lprcg)/FAS(lprcg) mice.

Yasuda T, Yoshimoto T, Tsubura A, Matsuzawa A.

Cell Immunol. 2001 Jun 15;210(2):77-86.

PMID:
11520074
[PubMed - indexed for MEDLINE]
15.

AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4.

White CA, Seth Hawkins J, Pone EJ, Yu ES, Al-Qahtani A, Mai T, Zan H, Casali P.

Autoimmunity. 2011 Dec;44(8):585-98. doi: 10.3109/08916934.2011.577128. Epub 2011 May 18. Erratum in: Autoimmunity. 2011 Dec;44(8):664.

PMID:
21585311
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Use of genetic knockouts to modulate disease expression in a murine model of lupus, MRL/lpr mice.

Reilly CM, Gilkeson GS.

Immunol Res. 2002;25(2):143-53. Review.

PMID:
11999168
[PubMed - indexed for MEDLINE]
17.

Cd72(c) is a modifier gene that regulates Fas(lpr)-induced autoimmune disease.

Xu M, Hou R, Sato-Hayashizaki A, Man R, Zhu C, Wakabayashi C, Hirose S, Adachi T, Tsubata T.

J Immunol. 2013 Jun 1;190(11):5436-45. doi: 10.4049/jimmunol.1203576. Epub 2013 Apr 24.

PMID:
23616572
[PubMed - indexed for MEDLINE]
Free Article
18.

DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr) mice in vivo.

Lenert P, Yasuda K, Busconi L, Nelson P, Fleenor C, Ratnabalasuriar RS, Nagy PL, Ashman RF, Rifkin IR, Marshak-Rothstein A.

Arthritis Res Ther. 2009;11(3):R79. doi: 10.1186/ar2710. Epub 2009 May 28.

PMID:
19476613
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Interferon regulatory factor 5 is critical for the development of lupus in MRL/lpr mice.

Tada Y, Kondo S, Aoki S, Koarada S, Inoue H, Suematsu R, Ohta A, Mak TW, Nagasawa K.

Arthritis Rheum. 2011 Mar;63(3):738-48. doi: 10.1002/art.30183.

PMID:
21305501
[PubMed - indexed for MEDLINE]
Free Article
20.

Interleukin 6 (IL-6) deficiency delays lupus nephritis in MRL-Faslpr mice: the IL-6 pathway as a new therapeutic target in treatment of autoimmune kidney disease in systemic lupus erythematosus.

Cash H, Relle M, Menke J, Brochhausen C, Jones SA, Topley N, Galle PR, Schwarting A.

J Rheumatol. 2010 Jan;37(1):60-70. doi: 10.3899/jrheum.090194. Epub 2009 Dec 1.

PMID:
19955044
[PubMed - indexed for MEDLINE]

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