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Delivery of the co-expression plasmid pEndo-Si-Stat3 by attenuated Salmonella serovar typhimurium for prostate cancer treatment.

Li X, Li Y, Wang B, Ji K, Liang Z, Guo B, Hu J, Yin D, Du Y, Kopecko DJ, Kalvakolanu DV, Zhao X, Xu D, Zhang L.

J Cancer Res Clin Oncol. 2013 Jun;139(6):971-80. doi: 10.1007/s00432-013-1398-0. Epub 2013 Mar 5.


Targeted therapy via oral administration of attenuated Salmonella expression plasmid-vectored Stat3-shRNA cures orthotopically transplanted mouse HCC.

Tian Y, Guo B, Jia H, Ji K, Sun Y, Li Y, Zhao T, Gao L, Meng Y, Kalvakolanu DV, Kopecko DJ, Zhao X, Zhang L, Xu D.

Cancer Gene Ther. 2012 Jun;19(6):393-401. doi: 10.1038/cgt.2012.12. Epub 2012 May 4.


Intratumoral delivery and suppression of prostate tumor growth by attenuated Salmonella enterica serovar typhimurium carrying plasmid-based small interfering RNAs.

Zhang L, Gao L, Zhao L, Guo B, Ji K, Tian Y, Wang J, Yu H, Hu J, Kalvakolanu DV, Kopecko DJ, Zhao X, Xu DQ.

Cancer Res. 2007 Jun 15;67(12):5859-64. Erratum in: Cancer Res. 2010 Jul 1;70(13):5639.


Recombinant attenuated Salmonella typhimurium carrying a plasmid co-expressing ENDO-VEGI151 and survivin siRNA inhibits the growth of breast cancer in vivo.

Li Z, Yin PH, Yang SS, Li QY, Chang T, Fang L, Shi LX, Fang GE.

Mol Med Rep. 2013 Apr;7(4):1215-22. doi: 10.3892/mmr.2013.1308. Epub 2013 Feb 5.


Plasmid-based Survivin shRNA and GRIM-19 carried by attenuated Salmonella suppresses tumor cell growth.

Liu YB, Zhang L, Guo YX, Gao LF, Liu XC, Zhao LJ, Guo BF, Zhao LJ, Zhao XJ, Xu DQ.

Asian J Androl. 2012 Jul;14(4):536-45. doi: 10.1038/aja.2011.179. Epub 2012 May 14.


[Inhibitory effect of silencing STAT3 gene with short hairpin RNA mediated by polyamidoamine dendrimers on growth of prostate cancer].

Zhao WM, Xiu YC, Xu Y, Wang YM, Cheng ZK, Yu Q, Kong DL.

Zhonghua Zhong Liu Za Zhi. 2007 Aug;29(8):575-9. Chinese.


Antitumor effects of Stat3-siRNA and endostatin combined therapies, delivered by attenuated Salmonella, on orthotopically implanted hepatocarcinoma.

Jia H, Li Y, Zhao T, Li X, Hu J, Yin D, Guo B, Kopecko DJ, Zhao X, Zhang L, Xu DQ.

Cancer Immunol Immunother. 2012 Nov;61(11):1977-87. doi: 10.1007/s00262-012-1256-y. Epub 2012 Apr 18.


Plasmid-based Stat3 siRNA delivered by hydroxyapatite nanoparticles suppresses mouse prostate tumour growth in vivo.

Liang ZW, Guo BF, Li Y, Li XJ, Li X, Zhao LJ, Gao LF, Yu H, Zhao XJ, Zhang L, Yang BX.

Asian J Androl. 2011 May;13(3):481-6. doi: 10.1038/aja.2010.167. Epub 2011 Feb 7.


Effects of plasmid-based Stat3-specific short hairpin RNA and GRIM-19 on PC-3M tumor cell growth.

Zhang L, Gao L, Li Y, Lin G, Shao Y, Ji K, Yu H, Hu J, Kalvakolanu DV, Kopecko DJ, Zhao X, Xu DQ.

Clin Cancer Res. 2008 Jan 15;14(2):559-68. doi: 10.1158/1078-0432.CCR-07-1176.


[Construction of RNA recombinant vector expressing STAT3 short hairpin and its effects on proliferation and apoptosis of SiHa cells].

Wu WG, Yu YC, Chen YQ, Cao XQ.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2008 Oct;24(10):986-8. Chinese.


Lentivirus-mediated shRNA interference targeting vascular endothelial growth factor inhibits angiogenesis and progression of human pancreatic carcinoma.

Zhao X, Zhu DM, Gan WJ, Li Z, Zhang JL, Zhao H, Zhou J, Li DC.

Oncol Rep. 2013 Mar;29(3):1019-26. doi: 10.3892/or.2012.2203. Epub 2012 Dec 19.


Synergistic suppression of prostatic cancer cells by coexpression of both murine double minute 2 small interfering RNA and wild-type p53 gene in vitro and in vivo.

Ji K, Wang B, Shao YT, Zhang L, Liu YN, Shao C, Li XJ, Li X, Hu JD, Zhao XJ, Xu DQ, Li Y, Cai L.

J Pharmacol Exp Ther. 2011 Jul;338(1):173-83. doi: 10.1124/jpet.111.180364. Epub 2011 Mar 28.


Tissue-selective RNA interference in prostate cancer cell using prostate specific membrane antigen promoter/enhancer.

Zhao W, Xu Y, Kong D, Liu R, Zhang Z, Jin C, Zhang Z, Xiu Y.

Urol Oncol. 2009 Sep-Oct;27(5):539-47. doi: 10.1016/j.urolonc.2008.05.003. Epub 2008 Jul 17.


[Double suicide gene therapy with RNAi targeting to STAT3 inhibits the growth of colorectal carcinoma cells in vitro].

Chen JY, Luo B, Guo XB, Wan LH.

Zhonghua Zhong Liu Za Zhi. 2011 Feb;33(2):91-6. Chinese.


Murine double minute 2 siRNA and wild-type p53 gene therapy interact positively with zinc on prostate tumours in vitro and in vivo.

Gu J, Wang B, Liu Y, Zhong L, Tang Y, Guo H, Jiang T, Wang L, Li Y, Cai L.

Eur J Cancer. 2014 Apr;50(6):1184-94. doi: 10.1016/j.ejca.2013.12.027. Epub 2014 Jan 18.


Synergistic effects of eukaryotic co-expression plasmid-based STAT3-specific siRNA and LKB1 on ovarian cancer in vitro and in vivo.

Pan Y, Zhang L, Zhang X, Liu R.

Oncol Rep. 2015 Feb;33(2):774-82. doi: 10.3892/or.2014.3623. Epub 2014 Nov 25.


Endostatin gene therapy delivered by Salmonella choleraesuis in murine tumor models.

Lee CH, Wu CL, Shiau AL.

J Gene Med. 2004 Dec;6(12):1382-93.


Down-regulation of signal transducer and activator of transcription 3 expression using vector-based small interfering RNAs suppresses growth of human prostate tumor in vivo.

Gao L, Zhang L, Hu J, Li F, Shao Y, Zhao D, Kalvakolanu DV, Kopecko DJ, Zhao X, Xu DQ.

Clin Cancer Res. 2005 Sep 1;11(17):6333-41.

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