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Results: 1 to 20 of 104

1.

MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency.

Gaspar-Maia A, Qadeer ZA, Hasson D, Ratnakumar K, Leu NA, Leroy G, Liu S, Costanzi C, Valle-Garcia D, Schaniel C, Lemischka I, Garcia B, Pehrson JR, Bernstein E.

Nat Commun. 2013;4:1565. doi: 10.1038/ncomms2582. Erratum in: Nat Commun. 2013;4:2090.

PMID:
23463008
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.

Mansour AA, Gafni O, Weinberger L, Zviran A, Ayyash M, Rais Y, Krupalnik V, Zerbib M, Amann-Zalcenstein D, Maza I, Geula S, Viukov S, Holtzman L, Pribluda A, Canaani E, Horn-Saban S, Amit I, Novershtern N, Hanna JH.

Nature. 2012 Aug 16;488(7411):409-13. doi: 10.1038/nature11272.

PMID:
22801502
[PubMed - indexed for MEDLINE]
3.

Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency.

Pasque V, Radzisheuskaya A, Gillich A, Halley-Stott RP, Panamarova M, Zernicka-Goetz M, Surani MA, Silva JC.

J Cell Sci. 2012 Dec 15;125(Pt 24):6094-104. doi: 10.1242/jcs.113019. Epub 2012 Oct 17.

PMID:
23077180
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency.

Sridharan R, Gonzales-Cope M, Chronis C, Bonora G, McKee R, Huang C, Patel S, Lopez D, Mishra N, Pellegrini M, Carey M, Garcia BA, Plath K.

Nat Cell Biol. 2013 Jul;15(7):872-82. doi: 10.1038/ncb2768. Epub 2013 Jun 9.

PMID:
23748610
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Histone variant macroH2A confers resistance to nuclear reprogramming.

Pasque V, Gillich A, Garrett N, Gurdon JB.

EMBO J. 2011 May 6;30(12):2373-87. doi: 10.1038/emboj.2011.144.

PMID:
21552206
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Macrohistone variants preserve cell identity by preventing the gain of H3K4me2 during reprogramming to pluripotency.

Barrero MJ, Sese B, Kuebler B, Bilic J, Boue S, Martí M, Izpisua Belmonte JC.

Cell Rep. 2013 Apr 25;3(4):1005-11. doi: 10.1016/j.celrep.2013.02.029. Epub 2013 Mar 28.

PMID:
23545500
[PubMed - indexed for MEDLINE]
Free Article
7.

n-Butylidenephthalide (BP) maintains stem cell pluripotency by activating Jak2/Stat3 pathway and increases the efficiency of iPS cells generation.

Liu SP, Harn HJ, Chien YJ, Chang CH, Hsu CY, Fu RH, Huang YC, Chen SY, Shyu WC, Lin SZ.

PLoS One. 2012;7(9):e44024. doi: 10.1371/journal.pone.0044024. Epub 2012 Sep 7.

PMID:
22970157
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Global epiproteomic signatures distinguish embryonic stem cells from differentiated cells.

Dai B, Rasmussen TP.

Stem Cells. 2007 Oct;25(10):2567-74. Epub 2007 Jul 19.

PMID:
17641388
[PubMed - indexed for MEDLINE]
Free Article
9.

Generation of mouse induced pluripotent stem cells from different genetic backgrounds using Sleeping beauty transposon mediated gene transfer.

Muenthaisong S, Ujhelly O, Polgar Z, Varga E, Ivics Z, Pirity MK, Dinnyes A.

Exp Cell Res. 2012 Nov 15;318(19):2482-9. doi: 10.1016/j.yexcr.2012.07.014. Epub 2012 Jul 28.

PMID:
22846649
[PubMed - indexed for MEDLINE]
10.

Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier.

Watanabe A, Yamada Y, Yamanaka S.

Philos Trans R Soc Lond B Biol Sci. 2013 Jan 5;368(1609):20120292. doi: 10.1098/rstb.2012.0292. Review.

PMID:
23166402
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Extended self-renewal and accelerated reprogramming in the absence of Kdm5b.

Kidder BL, Hu G, Yu ZX, Liu C, Zhao K.

Mol Cell Biol. 2013 Dec;33(24):4793-810. doi: 10.1128/MCB.00692-13. Epub 2013 Oct 7.

PMID:
24100015
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Macro histone variants are critical for the differentiation of human pluripotent cells.

Barrero MJ, Sese B, Martí M, Izpisua Belmonte JC.

J Biol Chem. 2013 May 31;288(22):16110-6. doi: 10.1074/jbc.M113.466144. Epub 2013 Apr 17.

PMID:
23595991
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming.

Qin H, Blaschke K, Wei G, Ohi Y, Blouin L, Qi Z, Yu J, Yeh RF, Hebrok M, Ramalho-Santos M.

Hum Mol Genet. 2012 May 1;21(9):2054-67. doi: 10.1093/hmg/dds023. Epub 2012 Jan 27.

PMID:
22286172
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes.

Kumar R, DiMenna L, Schrode N, Liu TC, Franck P, Muñoz-Descalzo S, Hadjantonakis AK, Zarrin AA, Chaudhuri J, Elemento O, Evans T.

Nature. 2013 Aug 1;500(7460):89-92. doi: 10.1038/nature12299. Epub 2013 Jun 26.

PMID:
23803762
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Pluripotent reprogramming of fibroblasts by lentiviral mediated insertion of SOX2, C-MYC, and TCL-1A.

Picanço-Castro V, Russo-Carbolante E, Reis LC, Fraga AM, de Magalhães DA, Orellana MD, Panepucci RA, Pereira LV, Covas DT.

Stem Cells Dev. 2011 Jan;20(1):169-80. doi: 10.1089/scd.2009.0424. Epub 2010 Oct 29.

PMID:
20504151
[PubMed - indexed for MEDLINE]
16.

The Ink4/Arf locus is a barrier for iPS cell reprogramming.

Li H, Collado M, Villasante A, Strati K, Ortega S, Cañamero M, Blasco MA, Serrano M.

Nature. 2009 Aug 27;460(7259):1136-9. doi: 10.1038/nature08290. Epub 2009 Aug 9.

PMID:
19668188
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

MacroH2A1 regulates the balance between self-renewal and differentiation commitment in embryonic and adult stem cells.

Creppe C, Janich P, Cantariño N, Noguera M, Valero V, Musulén E, Douet J, Posavec M, Martín-Caballero J, Sumoy L, Di Croce L, Benitah SA, Buschbeck M.

Mol Cell Biol. 2012 Apr;32(8):1442-52. doi: 10.1128/MCB.06323-11. Epub 2012 Feb 13.

PMID:
22331466
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Derivation of novel human ground state naive pluripotent stem cells.

Gafni O, Weinberger L, Mansour AA, Manor YS, Chomsky E, Ben-Yosef D, Kalma Y, Viukov S, Maza I, Zviran A, Rais Y, Shipony Z, Mukamel Z, Krupalnik V, Zerbib M, Geula S, Caspi I, Schneir D, Shwartz T, Gilad S, Amann-Zalcenstein D, Benjamin S, Amit I, Tanay A, Massarwa R, Novershtern N, Hanna JH.

Nature. 2013 Dec 12;504(7479):282-6. doi: 10.1038/nature12745. Epub 2013 Oct 30.

PMID:
24172903
[PubMed - indexed for MEDLINE]
19.

Reprogramming factor expression initiates widespread targeted chromatin remodeling.

Koche RP, Smith ZD, Adli M, Gu H, Ku M, Gnirke A, Bernstein BE, Meissner A.

Cell Stem Cell. 2011 Jan 7;8(1):96-105. doi: 10.1016/j.stem.2010.12.001.

PMID:
21211784
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2.

Doege CA, Inoue K, Yamashita T, Rhee DB, Travis S, Fujita R, Guarnieri P, Bhagat G, Vanti WB, Shih A, Levine RL, Nik S, Chen EI, Abeliovich A.

Nature. 2012 Aug 30;488(7413):652-5. doi: 10.1038/nature11333.

PMID:
22902501
[PubMed - indexed for MEDLINE]

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