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Results: 1 to 20 of 102

1.

Fundamental role for HIF-1α in constitutive expression of human β defensin-1.

Kelly CJ, Glover LE, Campbell EL, Kominsky DJ, Ehrentraut SF, Bowers BE, Bayless AJ, Saeedi BJ, Colgan SP.

Mucosal Immunol. 2013 Nov;6(6):1110-8. doi: 10.1038/mi.2013.6. Epub 2013 Mar 6.

PMID:
23462909
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor.

Acosta-Iborra B, Elorza A, Olazabal IM, Martín-Cofreces NB, Martin-Puig S, Miró M, Calzada MJ, Aragonés J, Sánchez-Madrid F, Landázuri MO.

J Immunol. 2009 Mar 1;182(5):3155-64. doi: 10.4049/jimmunol.0801710.

PMID:
19234213
[PubMed - indexed for MEDLINE]
Free Article
3.

Hypoxia-inducible factor-dependent repression of equilibrative nucleoside transporter 2 attenuates mucosal inflammation during intestinal hypoxia.

Morote-Garcia JC, Rosenberger P, Nivillac NM, Coe IR, Eltzschig HK.

Gastroenterology. 2009 Feb;136(2):607-18. doi: 10.1053/j.gastro.2008.10.037. Epub 2008 Nov 1.

PMID:
19105964
[PubMed - indexed for MEDLINE]
4.

Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.

Hindryckx P, De Vos M, Jacques P, Ferdinande L, Peeters H, Olievier K, Bogaert S, Brinkman B, Vandenabeele P, Elewaut D, Laukens D.

J Immunol. 2010 Nov 15;185(10):6306-16. doi: 10.4049/jimmunol.1002541. Epub 2010 Oct 13.

PMID:
20943999
[PubMed - indexed for MEDLINE]
Free Article
5.

Hypoxia-inducible factor-1 (HIF-1) is a transcriptional activator of the TrkB neurotrophin receptor gene.

Martens LK, Kirschner KM, Warnecke C, Scholz H.

J Biol Chem. 2007 May 11;282(19):14379-88. Epub 2007 Mar 20.

PMID:
17374610
[PubMed - indexed for MEDLINE]
Free Article
6.

Induction of CD36 and thrombospondin-1 in macrophages by hypoxia-inducible factor 1 and its relevance in the inflammatory process.

Ortiz-Masià D, Díez I, Calatayud S, Hernández C, Cosín-Roger J, Hinojosa J, Esplugues JV, Barrachina MD.

PLoS One. 2012;7(10):e48535. doi: 10.1371/journal.pone.0048535. Epub 2012 Oct 31.

PMID:
23119050
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells.

Belaiba RS, Bonello S, Zähringer C, Schmidt S, Hess J, Kietzmann T, Görlach A.

Mol Biol Cell. 2007 Dec;18(12):4691-7. Epub 2007 Sep 26.

PMID:
17898080
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.

Mastrogiannaki M, Matak P, Keith B, Simon MC, Vaulont S, Peyssonnaux C.

J Clin Invest. 2009 May;119(5):1159-66. doi: 10.1172/JCI38499. Epub 2009 Apr 6.

PMID:
19352007
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Hypoxia-inducible factor-1alpha is constitutively expressed in murine Leydig cells and regulates 3beta-hydroxysteroid dehydrogenase type 1 promoter activity.

Lysiak JJ, Kirby JL, Tremblay JJ, Woodson RI, Reardon MA, Palmer LA, Turner TT.

J Androl. 2009 Mar-Apr;30(2):146-56. doi: 10.2164/jandrol.108.006155. Epub 2008 Oct 16.

PMID:
18930903
[PubMed - indexed for MEDLINE]
Free Article
10.

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha.

Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M.

Nature. 2008 Jun 5;453(7196):807-11. doi: 10.1038/nature06905. Epub 2008 Apr 23.

PMID:
18432192
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Chronic colitis induces expression of β-defensins in murine intestinal epithelial cells.

Rahman A, Fahlgren A, Sundstedt C, Hammarström S, Danielsson A, Hammarström ML.

Clin Exp Immunol. 2011 Jan;163(1):123-30. doi: 10.1111/j.1365-2249.2010.04282.x. Epub 2010 Oct 29.

PMID:
21039426
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Tumor necrosis factor α-induced hypoxia-inducible factor 1α-β-catenin axis regulates major histocompatibility complex class I gene activation through chromatin remodeling.

Ghosh S, Paul A, Sen E.

Mol Cell Biol. 2013 Jul;33(14):2718-31. doi: 10.1128/MCB.01254-12. Epub 2013 May 13.

PMID:
23671189
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Hypoxia up-regulates CD36 expression and function via hypoxia-inducible factor-1- and phosphatidylinositol 3-kinase-dependent mechanisms.

Mwaikambo BR, Yang C, Chemtob S, Hardy P.

J Biol Chem. 2009 Sep 25;284(39):26695-707. doi: 10.1074/jbc.M109.033480. Epub 2009 Jul 29.

PMID:
19640849
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Tissue transglutaminase constitutively activates HIF-1α promoter and nuclear factor-κB via a non-canonical pathway.

Kumar S, Mehta K.

PLoS One. 2012;7(11):e49321. doi: 10.1371/journal.pone.0049321. Epub 2012 Nov 19.

PMID:
23185316
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Hypoxia-inducible factor signaling provides protection in Clostridium difficile-induced intestinal injury.

Hirota SA, Fines K, Ng J, Traboulsi D, Lee J, Ihara E, Li Y, Willmore WG, Chung D, Scully MM, Louie T, Medlicott S, Lejeune M, Chadee K, Armstrong G, Colgan SP, Muruve DA, MacDonald JA, Beck PL.

Gastroenterology. 2010 Jul;139(1):259-69.e3. doi: 10.1053/j.gastro.2010.03.045. Epub 2010 Mar 27.

PMID:
20347817
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation.

Zhang X, Zhou K, Wang R, Cui J, Lipton SA, Liao FF, Xu H, Zhang YW.

J Biol Chem. 2007 Apr 13;282(15):10873-80. Epub 2007 Feb 15.

PMID:
17303576
[PubMed - indexed for MEDLINE]
Free Article
17.

The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes.

Chavez JC, Baranova O, Lin J, Pichiule P.

J Neurosci. 2006 Sep 13;26(37):9471-81.

PMID:
16971531
[PubMed - indexed for MEDLINE]
Free Article
18.

The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha.

Hu CJ, Sataur A, Wang L, Chen H, Simon MC.

Mol Biol Cell. 2007 Nov;18(11):4528-42. Epub 2007 Sep 5.

PMID:
17804822
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Advanced glycated end-products affect HIF-transcriptional activity in renal cells.

Bondeva T, Heinzig J, Ruhe C, Wolf G.

Mol Endocrinol. 2013 Nov;27(11):1918-33. doi: 10.1210/me.2013-1036. Epub 2013 Sep 12.

PMID:
24030251
[PubMed - indexed for MEDLINE]
20.

HIF-1-mediated up-regulation of cardiotrophin-1 is involved in the survival response of cardiomyocytes to hypoxia.

Robador PA, San José G, Rodríguez C, Guadall A, Moreno MU, Beaumont J, Fortuño A, Díez J, Martínez-González J, Zalba G.

Cardiovasc Res. 2011 Nov 1;92(2):247-55. doi: 10.1093/cvr/cvr202. Epub 2011 Jul 19.

PMID:
21771897
[PubMed - indexed for MEDLINE]
Free Article

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